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Osborne, Barbara

One or more keywords matched the following items that are connected to Osborne, Barbara

Item Type	Name
Academic Article	Costimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4(+)CD8(+) thymocytes.
Academic Article	Gene regulation associated with apoptosis.
Academic Article	Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells.
Academic Article	Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents.
Academic Article	Characterization of a mutant T-cell hybridoma line with defects in the TCR-mediated apoptotic pathway.
Academic Article	Arbiter of differentiation and death: Notch signaling meets apoptosis.
Academic Article	Notch and the immune system.
Academic Article	Notch1 augments NF-kappaB activity by facilitating its nuclear retention.
Academic Article	Off the beaten pathway: the complex cross talk between Notch and NF-kappaB.
Academic Article	Rational targeting of Notch signaling in cancer.
Academic Article	Notch regulates cytolytic effector function in CD8+ T cells.
Academic Article	Targeting Notch to target cancer stem cells.
Academic Article	Canonical and non-canonical Notch signaling in CD4? T cells.
Academic Article	Notch signaling is necessary but not sufficient for differentiation of dendritic cells.
Academic Article	TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells.
Academic Article	Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.
Academic Article	Programmed cell death, apoptosis and killer genes.
Academic Article	Notch signaling in cancer.
Academic Article	Notch signalling during peripheral T-cell activation and differentiation.
Academic Article	Notch signaling is activated by TLR stimulation and regulates macrophage functions.
Academic Article	Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells.
Academic Article	Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases.
Academic Article	Targeting Notch signaling cross-talk with estrogen receptor and ErbB-2 in breast cancer.
Academic Article	Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice.
Academic Article	Notch signaling regulates mouse and human Th17 differentiation.
Academic Article	Notch and the survival of regulatory T cells: location is everything!
Academic Article	Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28.
Concept	Signal Transduction
Academic Article	?-Secretase inhibitors and modulators.
Academic Article	Notch signaling regulates the phosphorylation of Akt and survival of lipopolysaccharide-activated macrophages via regulator of G protein signaling 19 (RGS19).
Academic Article	p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1.
Academic Article	Impact of Notch1 Deletion in Macrophages on Proinflammatory Cytokine Production and the Outcome of Experimental Autoimmune Encephalomyelitis.
Academic Article	Intracellular Delivery of Anti-pPKC? (Thr538) via Protein Transduction Domain Mimics for Immunomodulation.
Academic Article	Cellular Prion Protein Mediates Pancreatic Cancer Cell Survival and Invasion through Association with and Enhanced Signaling of Notch1.
Academic Article	Disparate metabolic response to fructose feeding between different mouse strains.
Academic Article	Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses.
Academic Article	Notch1 primes CD4 T cells for T helper type I differentiation through its early effects on miR-29.
Academic Article	Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes.
Academic Article	Notch and T Cell Function - A Complex Tale.
Academic Article	Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance.
Academic Article	?-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse ?-secretase modulators do not.
Academic Article	CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells.
Academic Article	Cell-Penetrating Anti-Protein Kinase C Theta Antibodies Act Intracellularly to Generate Stable, Highly Suppressive Regulatory T Cells.
Academic Article	Protein Kinase C Theta Modulates PCMT1 through hnRNPL to Regulate FOXP3 Stability in Regulatory T Cells.
Academic Article	Targeting Notch in oncology: the path forward.

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Signal Transduction