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Search Results to Igor Kaltashov PhD

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One or more keywords matched the following items that are connected to Kaltashov, Igor

Item TypeName
Academic Article Detection of multiple protein conformational ensembles in solution via deconvolution of charge-state distributions in ESI MS.
Academic Article Indirect assessment of small hydrophobic ligand binding to a model protein using a combination of ESI MS and HDX/ESI MS.
Academic Article Highly asymmetric interactions between globin chains during hemoglobin assembly revealed by electrospray ionization mass spectrometry.
Academic Article Mapping protein energy landscapes with amide hydrogen exchange and mass spectrometry: I. A generalized model for a two-state protein and comparison with experiment.
Academic Article Unfolding dynamics of a beta-sheet protein studied by mass spectrometry.
Academic Article Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches.
Academic Article Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling.
Academic Article Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: conformational heterogeneity of alpha-synuclein.
Academic Article Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry.
Academic Article Controlling hydrogen scrambling in multiply charged protein ions during collisional activation: implications for top-down hydrogen/deuterium exchange MS utilizing collisional activation in the gas phase.
Academic Article Properties of a homogeneous C-lobe prepared by introduction of a TEV cleavage site between the lobes of human transferrin.
Academic Article Direct monitoring of heat-stressed biopolymers with temperature-controlled electrospray ionization mass spectrometry.
Academic Article Detection and characterization of large-scale protein conformational transitions in solution using charge-state distribution analysis in ESI-MS.
Academic Article Studies of biomolecular conformations and conformational dynamics by mass spectrometry.
Academic Article Mass spectrometry-based methods to study protein architecture and dynamics.
Academic Article Interlobe communication in human serum transferrin: metal binding and conformational dynamics investigated by electrospray ionization mass spectrometry.
Academic Article A chemometric approach to detection and characterization of multiple protein conformers in solution using electrospray ionization mass spectrometry.
Academic Article Transient structural disorder as a facilitator of protein-ligand binding: native H/D exchange-mass spectrometry study of cellular retinoic acid binding protein I.
Academic Article Extraction of local hydrogen exchange data from HDX CAD MS measurements by deconvolution of isotopic distributions of fragment ions.
Academic Article Protein conformational heterogeneity as a binding catalyst: ESI-MS study of hemoglobin H formation.
Academic Article Gas-phase interference-free analysis of protein ion charge-state distributions: detection of small-scale conformational transitions accompanying pepsin inactivation.
Academic Article Do ionic charges in ESI MS provide useful information on macromolecular structure?
Academic Article Structural and functional consequences of the substitution of glycine 65 with arginine in the N-lobe of human transferrin.
Academic Article Existence of a noncanonical state of iron-bound transferrin at endosomal pH revealed by hydrogen exchange and mass spectrometry.
Academic Article H/D exchange and mass spectrometry in the studies of protein conformation and dynamics: is there a need for a top-down approach?
Academic Article Impact of oxidation on protein therapeutics: conformational dynamics of intact and oxidized acid-ß-glucocerebrosidase at near-physiological pH.
Academic Article Advanced mass spectrometry-based methods for the analysis of conformational integrity of biopharmaceutical products.
Academic Article Advances and challenges in analytical characterization of biotechnology products: mass spectrometry-based approaches to study properties and behavior of protein therapeutics.
Concept Protein Conformation
Academic Article Conformer-specific characterization of nonnative protein states using hydrogen exchange and top-down mass spectrometry.
Academic Article Enhancing the quality of H/D exchange measurements with mass spectrometry detection in disulfide-rich proteins using electron capture dissociation.
Academic Article Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid.
Academic Article Characterization of intact protein conjugates and biopharmaceuticals using ion-exchange chromatography with online detection by native electrospray ionization mass spectrometry and top-down tandem mass spectrometry.

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  • Protein Conformation