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Reduced amounts and abnormal forms of phospholipase C zeta (PLCzeta) in spermatozoa from infertile men.
Complete globozoospermia associated with PLC? deficiency treated with calcium ionophore and ICSI results in pregnancy.
A maternally inherited autosomal point mutation in human phospholipase C zeta (PLC?) leads to male infertility.
Identification of phospholipase C zeta in normospermic and teratospermic domestic cat sperm.
Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development.
Subcellular localization of phospholipase C? in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation.
Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP.
Male Infertility: Genetics, Mechanism, and Therapies.
Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models.
The eggstraordinary story of how life begins.
Defective sperm head decondensation undermines the success of ICSI in the bovine.