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Estradiol stimulates the biosynthetic pathways of breast cancer cells: detection by metabolic flux analysis.
Integrating cell-cycle progression, drug penetration and energy metabolism to identify improved cancer therapeutic strategies.
Efficient gene delivery vectors by tuning the surface charge density of amino acid-functionalized gold nanoparticles.
Motility is critical for effective distribution and accumulation of bacteria in tumor tissue.
Incorporating energy metabolism into a growth model of multicellular tumor spheroids.
Flux analysis shows that hypoxia-inducible-factor-1-alpha minimally affects intracellular metabolism in tumor spheroids.
Tuning payload delivery in tumour cylindroids using gold nanoparticles.
Microfluidic technique to measure intratumoral transport and calculate drug efficacy shows that binding is essential for doxorubicin and release hampers Doxil.
Persistent enhancement of bacterial motility increases tumor penetration.
Tissue transport affects how treatment scheduling increases the efficacy of chemotherapeutic drugs.
Mucus blocks probiotics but increases penetration of motile pathogens and induces TNF-? and IL-8 secretion.