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Debold, Edward
One or more keywords matched the following items that are connected to Debold, Edward
Item TypeName
Academic Article Phosphate enhances myosin-powered actin filament velocity under acidic conditions in a motility assay.
Academic Article Mechanical coupling between myosin molecules causes differences between ensemble and single-molecule measurements.
Academic Article The effects of phosphate and acidosis on regulated thin-filament velocity in an in vitro motility assay.
Academic Article Slip sliding away: load-dependence of velocity generated by skeletal muscle myosin molecules in the laser trap.
Academic Article Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.
Academic Article Human actin mutations associated with hypertrophic and dilated cardiomyopathies demonstrate distinct thin filament regulatory properties in vitro.
Concept Actins
Concept Actin Cytoskeleton
Academic Article Ca++-sensitizing mutations in troponin, P(i), and 2-deoxyATP alter the depressive effect of acidosis on regulated thin-filament velocity.
Academic Article Magnesium modulates actin binding and ADP release in myosin motors.
Academic Article The molecular basis of thin filament activation: from single molecule to muscle.
Academic Article Acidosis affects muscle contraction by slowing the rates myosin attaches to and detaches from actin.
Academic Article Acidosis decreases the Ca2+ sensitivity of thin filaments by preventing the first actomyosin interaction.
Academic Article Positional Isomers of a Non-Nucleoside Substrate Differentially Affect Myosin Function.
Academic Article FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V.
Academic Article Myosin's powerstroke occurs prior to the release of phosphate from the active site.
Academic Article Recent insights into the relative timing of myosin's powerstroke and release of phosphate.
Academic Article A mutation in switch I alters the load-dependent kinetics of myosin Va.
Academic Article Modeling thick filament activation suggests a molecular basis for force depression.
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  • Actins