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Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca(2+) sparks in airway myocytes.
Ca(2+) spark sites in smooth muscle cells are numerous and differ in number of ryanodine receptors, large-conductance K(+) channels, and coupling ratio between them.
Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle.
Large-Conductance Calcium-Activated Potassium Channels
Potassium Channels, Calcium-Activated