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PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans.
C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts.
piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline.
CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors.
The C. elegans CSR-1 argonaute pathway counteracts epigenetic silencing to promote germline gene expression.
HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans.
PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans.