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Zamore, Phillip
One or more keywords matched the following properties of Zamore, Phillip
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Rotation Projects

Potential Rotation Projects

Our laboratory uses a combination of biochemistry, cell biology, and genetics to dissect the RNAi pathway. A rotation project is available to explore the mechanisms that underlie the RNAi phenomenon or the biological pathways in which RNAi enzymes participate in flies, mice and humans.
One or more keywords matched the following items that are connected to Zamore, Phillip
Item TypeName
Academic Article RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals.
Academic Article Ancient pathways programmed by small RNAs.
Academic Article The PUMILIO-RNA interaction: a single RNA-binding domain monomer recognizes a bipartite target sequence.
Academic Article Asymmetry in the assembly of the RNAi enzyme complex.
Academic Article Molecular biology. RNA interference.
Academic Article Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells.
Academic Article Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells.
Academic Article The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters.
Academic Article Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence.
Academic Article Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.
Academic Article A microRNA in a multiple-turnover RNAi enzyme complex.
Academic Article Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery.
Academic Article A distinct small RNA pathway silences selfish genetic elements in the germline.
Academic Article RNA silencing: genomic defence with a slice of pi.
Academic Article Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains.
Academic Article Adaptation to P element transposon invasion in Drosophila melanogaster.
Academic Article UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery.
Academic Article Small RNA-directed silencing: the fly finds its inner fission yeast?
Concept Antisense Elements (Genetics)
Concept Response Elements
Concept Oligonucleotides, Antisense
Concept RNA, Antisense
Concept DNA Transposable Elements
Academic Article Antisense piRNA amplification, but not piRNA production or nuage assembly, requires the Tudor-domain protein Qin.
Academic Article piPipes: a set of pipelines for piRNA and transposon analysis via small RNA-seq, RNA-seq, degradome- and CAGE-seq, ChIP-seq and genomic DNA sequencing.
Academic Article Slicing and Binding by Ago3 or Aub Trigger Piwi-Bound piRNA Production by Distinct Mechanisms.
Academic Article Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements.
Academic Article Preparation of Antisense Oligonucleotides to Inhibit miRNA Function.
Academic Article Inhibiting miRNA Function by Antisense Oligonucleotides in Cultured Mammalian Cells.
Academic Article PIWI-interacting RNAs: small RNAs with big functions.
Academic Article Inhibiting miRNA Function by Antisense Oligonucleotides in Drosophila S2 Cells.
Academic Article Maelstrom Represses Canonical Polymerase II Transcription within Bi-directional piRNA Clusters in Drosophila melanogaster.
Academic Article Defining the functions of PIWI-interacting RNAs.
Academic Article Relaxed targeting rules help PIWI proteins silence transposons.
Search Criteria
  • Antisense
  • Elements
  • Genetics