Item Type | Name |
Academic Article
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A CCHC metal-binding domain in Nanos is essential for translational regulation.
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Academic Article
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The Pumilio protein binds RNA through a conserved domain that defines a new class of RNA-binding proteins.
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Academic Article
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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA.
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Academic Article
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The PUMILIO-RNA interaction: a single RNA-binding domain monomer recognizes a bipartite target sequence.
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Academic Article
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Asymmetry in the assembly of the RNAi enzyme complex.
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Academic Article
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Kinetic analysis of the RNAi enzyme complex.
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Academic Article
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Targeted mRNA degradation by double-stranded RNA in vitro.
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Academic Article
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Measuring the rates of transcriptional elongation in the female Drosophila melanogaster germ line by nuclear run-on.
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Academic Article
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The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC.
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Academic Article
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Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.
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Academic Article
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Argonaute loading improves the 5' precision of both MicroRNAs and their miRNA* strands in flies.
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Academic Article
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Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells.
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Academic Article
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Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies.
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Academic Article
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The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters.
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Academic Article
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Target RNA-directed trimming and tailing of small silencing RNAs.
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Academic Article
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Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins.
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Academic Article
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Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence.
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Academic Article
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The 3'-to-5' exoribonuclease Nibbler shapes the 3' ends of microRNAs bound to Drosophila Argonaute1.
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Academic Article
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A microRNA in a multiple-turnover RNAi enzyme complex.
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Academic Article
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Argonaute divides its RNA guide into domains with distinct functions and RNA-binding properties.
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Academic Article
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Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.
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Academic Article
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In vitro analysis of RNA interference in Drosophila melanogaster.
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Academic Article
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Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis.
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Academic Article
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Biochemical dissection of RNA silencing in plants.
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Academic Article
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RISC assembly defects in the Drosophila RNAi mutant armitage.
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Academic Article
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The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA.
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Academic Article
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Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein.
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Academic Article
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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes.
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Academic Article
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A distinct small RNA pathway silences selfish genetic elements in the germline.
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Academic Article
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RNA silencing: genomic defence with a slice of pi.
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Academic Article
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Sorting of Drosophila small silencing RNAs.
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Academic Article
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A role for microRNAs in the Drosophila circadian clock.
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Academic Article
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Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease.
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Academic Article
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Isolation of Drosophila melanogaster testes.
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Academic Article
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Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains.
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Academic Article
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Adaptation to P element transposon invasion in Drosophila melanogaster.
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Academic Article
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Dicer partner proteins tune the length of mature miRNAs in flies and mammals.
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Academic Article
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UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery.
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Academic Article
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Small RNA-directed silencing: the fly finds its inner fission yeast?
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Concept
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Drosophila melanogaster
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Academic Article
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Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain.
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Academic Article
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A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis.
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Academic Article
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The HP1 homolog rhino anchors a nuclear complex that suppresses piRNA precursor splicing.
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Academic Article
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The initial uridine of primary piRNAs does not create the tenth adenine that Is the hallmark of secondary piRNAs.
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Academic Article
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piPipes: a set of pipelines for piRNA and transposon analysis via small RNA-seq, RNA-seq, degradome- and CAGE-seq, ChIP-seq and genomic DNA sequencing.
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Academic Article
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Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified.
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Academic Article
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Noncoding RNA. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production.
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Academic Article
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Assessing long-distance RNA sequence connectivity via RNA-templated DNA-DNA ligation.
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Academic Article
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Slicing and Binding by Ago3 or Aub Trigger Piwi-Bound piRNA Production by Distinct Mechanisms.
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Academic Article
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Tailor: a computational framework for detecting non-templated tailing of small silencing RNAs.
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Academic Article
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Rapid Screening for CRISPR-Directed Editing of the Drosophila Genome Using white Coconversion.
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Academic Article
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A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most Animals.
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Academic Article
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Maelstrom Represses Canonical Polymerase II Transcription within Bi-directional piRNA Clusters in Drosophila melanogaster.
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Academic Article
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The RNA-Binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria.
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Academic Article
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Terminal modification, sequence, length, and PIWI-protein identity determine piRNA stability.
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Academic Article
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A maternally programmed intergenerational mechanism enables male offspring to make piRNAs from Y-linked precursor RNAs in Drosophila.
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