| Item Type | Name |
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Academic Article
|
RNA-binding proteins that specifically recognize the selenocysteine insertion sequence of human cellular glutathione peroxidase mRNA.
|
|
Academic Article
|
Partial reconstitution of the respiratory burst oxidase in lymphoblastoid B cell lines lacking p67-phox after transfection with an expression vector containing wild-type and mutant p67 -phox cDNAs: Deletions of the carboxy and amino terminal residues of p67-phox are not required for activity.
|
|
Academic Article
|
Identification and molecular cloning of a human selenocysteine insertion sequence-binding protein. A bifunctional role for DNA-binding protein B.
|
|
Academic Article
|
The effect of IFN-gamma and TNF-alpha on the NADPH oxidase system of human colostrum macrophages, blood monocytes, and THP-1 cells.
|
|
Academic Article
|
Recognition and binding of the human selenocysteine insertion sequence by nucleolin.
|
|
Academic Article
|
Interferon-gamma improves splicing efficiency of CYBB gene transcripts in an interferon-responsive variant of chronic granulomatous disease due to a splice site consensus region mutation.
|
|
Academic Article
|
Mosaic tetraploidy and transient GFI1 mutation in a patient with severe chronic neutropenia.
|
|
Academic Article
|
RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells.
|
|
Academic Article
|
Genomic and proteomic analysis of the myeloid differentiation program.
|
|
Academic Article
|
Partial correction of the phagocyte defect in patients with X-linked chronic granulomatous disease by subcutaneous interferon gamma.
|
|
Academic Article
|
Neutrophil defect associated with malignant infantile osteopetrosis.
|
|
Academic Article
|
Changes in superoxide dismutase, catalase, and the glutathione cycle during induced myeloid differentiation.
|
|
Academic Article
|
Cloning the gene for the inherited disorder chronic granulomatous disease on the basis of its chromosomal location.
|
|
Academic Article
|
Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line.
|
|
Academic Article
|
Chronic granulomatous disease. Expression of the metabolic defect by in vitro culture of bone marrow progenitors.
|
|
Academic Article
|
Opsonized zymosan-stimulated granulocytes-activation and activity of the superoxide-generating system and membrane potential changes.
|
|
Academic Article
|
Human neutrophil dysfunction with giant granules and defective activation of the respiratory burst.
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|
Academic Article
|
Eosinophilic cytoplasmic inclusions in fetal leukocytes: are Auer bodies a recapitulation of fetal morphology?
|
|
Academic Article
|
Human granulocytes generated in continuous bone marrow culture are physiologically normal.
|
|
Academic Article
|
Structure and function of the selenium translation element in the 3'-untranslated region of human cellular glutathione peroxidase mRNA.
|
|
Academic Article
|
Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA.
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|
Academic Article
|
Chemotactic peptide-induced cytoplasmic pH changes in incubated human monocytes.
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|
Academic Article
|
Esophagitis induced by combined radiation and adriamycin.
|
|
Academic Article
|
Chronic granulomatous disease in Latin American patients: clinical spectrum and molecular genetics.
|
|
Academic Article
|
The American Society of Pediatric Hematology/Oncology distinguished career award goes to Laurence A. Boxer, MD.
|
|
Academic Article
|
Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS).
|
|
Academic Article
|
Cyclic neutropenia and severe congenital neutropenia in patients with a shared ELANE mutation and paternal haplotype: evidence for phenotype determination by modifying genes.
|
|
Academic Article
|
Hemophagocytic lymphohistiocytosis with MUNC13-4 gene mutation or reduced natural killer cell function prior to onset of childhood leukemia.
|
|
Academic Article
|
Induction of phagocyte cytochrome b heavy chain gene expression by interferon gamma.
|
|
Academic Article
|
Modulation of mononuclear phagocyte cytotoxicity by alpha-tocopherol (vitamin E).
|
|
Academic Article
|
Evaluation and management of patients with isolated neutropenia.
|
|
Academic Article
|
Activity and activation of the granulocyte superoxide-generating system.
|
|
Academic Article
|
Functionally deficient differentiation of HL-60 promyelocytic leukemia cells induced by phorbol myristate acetate.
|
|
Academic Article
|
Impaired granulocyte superoxide production and prolongation of the respiratory burst due to a low-affinity NADPH-dependent oxidase.
|
|
Academic Article
|
Phorbol myristate acetate stimulates macrophage differentiation and replication and alters granulopoiesis and leukemogenesis in long-term bone marrow cultures.
|
|
Academic Article
|
Selenium regulation of glutathione peroxidase in human hepatoma cell line Hep3B.
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|
Concept
|
Methylprednisolone
|
|
Concept
|
Antineoplastic Combined Chemotherapy Protocols
|
|
Concept
|
Vesicular Transport Proteins
|
|
Concept
|
Mycobacterium Infections
|
|
Concept
|
Cytokines
|
|
Concept
|
Aluminum
|
|
Concept
|
Inhibitor of Differentiation Protein 2
|
|
Concept
|
Neutrophils
|
|
Concept
|
Karyotyping
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Precision Medicine
|
|
Concept
|
Dexamethasone
|
|
Concept
|
DNA Methylation
|
|
Concept
|
Piebaldism
|
|
Concept
|
Temperature
|
|
Concept
|
Chediak-Higashi Syndrome
|
|
Concept
|
Selenium
|
|
Concept
|
Databases, Factual
|
|
Concept
|
Granulocyte Colony-Stimulating Factor
|
|
Concept
|
Phorbols
|
|
Concept
|
Brain Neoplasms
|
|
Concept
|
Receptors, Somatotropin
|
|
Concept
|
Agranulocytosis
|
|
Concept
|
Nitroblue Tetrazolium
|
|
Concept
|
Survival Rate
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Health Services Accessibility
|
|
Concept
|
Interferon-gamma
|
|
Concept
|
Base Pairing
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Humans
|
|
Concept
|
Serum Albumin, Bovine
|
|
Concept
|
Dimethylformamide
|
|
Concept
|
Erythroid Precursor Cells
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
|
Concept
|
CD4 Antigens
|
|
Concept
|
Introns
|
|
Concept
|
Erythropoietin
|
|
Concept
|
Recurrence
|
|
Concept
|
Doxorubicin
|
|
Concept
|
Epstein-Barr Virus Nuclear Antigens
|
|
Concept
|
Precursor Cell Lymphoblastic Leukemia-Lymphoma
|
|
Concept
|
Methylmannosides
|
|
Concept
|
Cell Division
|
|
Concept
|
Pollen
|
|
Concept
|
Qa-SNARE Proteins
|
|
Concept
|
Magnetic Resonance Imaging
|
|
Concept
|
Actins
|
|
Concept
|
Trisomy
|
|
Concept
|
Hematologic Neoplasms
|
|
Concept
|
COS Cells
|
|
Concept
|
Membrane Potentials
|
|
Concept
|
Lentivirus
|
|
Concept
|
Metabolic Clearance Rate
|
|
Concept
|
Patient Care Team
|
|
Concept
|
Mutagenesis, Site-Directed
|
|
Concept
|
Leukemia, Lymphoid
|
|
Concept
|
Fathers
|
|
Concept
|
Starch
|
|
Concept
|
Fluorescent Dyes
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Polymorphism, Single Nucleotide
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Disease Progression
|
|
Concept
|
Antigen-Antibody Complex
|
|
Concept
|
Myelopoiesis
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
Neomycin
|
|
Concept
|
Hematopoietic Cell Growth Factors
|
|
Concept
|
Electric Stimulation Therapy
|
|
Concept
|
Receptors, Cell Surface
|
|
Concept
|
Medical Oncology
|
|
Concept
|
HSP70 Heat-Shock Proteins
|
|
Concept
|
Genes, X-Linked
|
|
Concept
|
Leukemia, Myeloid
|
|
Concept
|
Registries
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Receptors, Interferon
|
|
Concept
|
Toll-Like Receptors
|
|
Concept
|
History, 21st Century
|
|
Concept
|
Macrophages
|
|
Concept
|
Bone Marrow Transplantation
|
|
Concept
|
Tretinoin
|
|
Concept
|
TATA Box
|
|
Concept
|
HIV-1
|
|
Concept
|
Quinacrine Mustard
|
|
Concept
|
Cricetinae
|
|
Concept
|
Fibronectins
|
|
Concept
|
Minisatellite Repeats
|
|
Concept
|
Lysosomes
|
|
Concept
|
Genes, Viral
|
|
Concept
|
Macrolides
|
|
Concept
|
Genetic Testing
|
|
Concept
|
Dogs
|
|
Concept
|
Amino Acid Substitution
|
|
Concept
|
Receptors, Laminin
|
|
Concept
|
Jurkat Cells
|
|
Concept
|
Receptors, Transferrin
|
|
Concept
|
Animals
|
|
Concept
|
Leukopenia
|
|
Concept
|
Syndrome
|
|
Concept
|
Histamine
|
|
Concept
|
Chronic Disease
|
|
Concept
|
Rauscher Virus
|
|
Concept
|
Synaptic Transmission
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Glucosephosphate Dehydrogenase Deficiency
|
|
Concept
|
Chromosomes, Human
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Immunosuppressive Agents
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Antibodies
|
|
Concept
|
Pyruvate Metabolism, Inborn Errors
|
|
Concept
|
Photosystem II Protein Complex
|
|
Concept
|
Leukemia
|
|
Concept
|
Mice, Inbred C3H
|
|
Concept
|
Calcium
|
|
Concept
|
Vitamin B 12
|
|
Concept
|
Precipitin Tests
|
|
Concept
|
Hydrogen Peroxide
|
|
Concept
|
Iron Overload
|
|
Concept
|
Ethylmaleimide
|
|
Concept
|
DNA Copy Number Variations
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Lymphoma
|
|
Concept
|
Toll-Like Receptor 4
|
|
Concept
|
Salicylates
|
|
Concept
|
Friend murine leukemia virus
|
|
Concept
|
Lipopolysaccharides
|
|
Concept
|
Injections, Subcutaneous
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Translocation, Genetic
|
|
Concept
|
Interleukin-1 Receptor-Associated Kinases
|
|
Concept
|
Cricetulus
|
|
Concept
|
Anti-Inflammatory Agents, Non-Steroidal
|
|
Concept
|
Hydrocortisone
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
Disease Management
|
|
Concept
|
Latex
|
|
Concept
|
Luminescent Measurements
|
|
Concept
|
Biopsy
|
|
Concept
|
Radiation Injuries
|
|
Concept
|
Germinal Center
|
|
Concept
|
Dose-Response Relationship, Drug
|
|
Concept
|
Nanoparticles
|
|
Concept
|
Iron
|
|
Concept
|
Biopsy, Needle
|
|
Concept
|
Concanavalin A
|
|
Concept
|
Leukocyte Count
|
|
Concept
|
Nucleotidases
|
|
Concept
|
Granulomatous Disease, Chronic
|
|
Concept
|
Interleukin-5
|
|
Concept
|
CD11c Antigen
|
|
Concept
|
Mice
|
|
Concept
|
Clinical Trials as Topic
|
|
Concept
|
Microspheres
|
|
Concept
|
DNA Primers
|
|
Concept
|
Gene Expression Regulation, Leukemic
|
|
Concept
|
Macrophage Activation Syndrome
|
|
Concept
|
Histocytochemistry
|
|
Concept
|
Germ-Line Mutation
|
|
Concept
|
Spectrin
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Live Birth
|
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
|
Concept
|
Insulator Elements
|
|
Concept
|
Conserved Sequence
|
|
Concept
|
Glutathione Peroxidase
|
|
Concept
|
Butyric Acid
|
|
Concept
|
Lactoferrin
|
|
Concept
|
Cattle
|
|
Concept
|
gamma-Globulins
|
|
Concept
|
Growth Substances
|
|
Concept
|
Adjuvants, Immunologic
|
|
Concept
|
Mutagenesis, Insertional
|
|
Concept
|
Codon
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
Mosaicism
|
|
Concept
|
Lysine
|
|
Concept
|
Embryo Loss
|
|
Concept
|
GATA1 Transcription Factor
|
|
Concept
|
Anti-Inflammatory Agents
|
|
Concept
|
Leukocyte Elastase
|
|
Concept
|
Toll-Like Receptor 2
|
|
Concept
|
Sequence Deletion
|
|
Concept
|
Toll-Like Receptor 7
|
|
Concept
|
Colony-Forming Units Assay
|
|
Concept
|
Cell Movement
|
|
Concept
|
Laminin
|
|
Concept
|
Consensus Sequence
|
|
Concept
|
Influenza A Virus, H3N2 Subtype
|
|
Concept
|
Palatine Tonsil
|
|
Concept
|
Liver Neoplasms
|
|
Concept
|
Cell Separation
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Herpesvirus 4, Human
|
|
Concept
|
Oxygen
|
|
Concept
|
Tetradecanoylphorbol Acetate
|
|
Concept
|
Granulocyte-Macrophage Colony-Stimulating Factor
|
|
Concept
|
Cytopathogenic Effect, Viral
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Epitopes
|
|
Concept
|
Chickens
|
|
Concept
|
N-Formylmethionine Leucyl-Phenylalanine
|
|
Concept
|
Monocytes
|
|
Concept
|
Nucleic Acid Conformation
|
|
Concept
|
RNA Splice Sites
|
|
Concept
|
Tuberculosis
|
|
Concept
|
Immunoglobulin G
|
|
Concept
|
Integrin alpha6
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Anemia, Diamond-Blackfan
|
|
Concept
|
Pilot Projects
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Methods
|
|
Concept
|
DNA, Viral
|
|
Concept
|
Haptens
|
|
Concept
|
Comparative Genomic Hybridization
|
|
Concept
|
Hermanski-Pudlak Syndrome
|
|
Concept
|
History, 20th Century
|
|
Concept
|
Integrin beta1
|
|
Concept
|
Sepsis
|
|
Concept
|
Angioplasty, Balloon
|
|
Concept
|
Phospholipids
|
|
Concept
|
Helix-Loop-Helix Motifs
|
|
Concept
|
Iodide Peroxidase
|
|
Concept
|
Chromosomes, Human, X
|
|
Concept
|
Hypnosis
|
|
Concept
|
Inflammation
|
|
Concept
|
Leukemia, Monocytic, Acute
|
|
Concept
|
Ascaris
|
|
Concept
|
Ionophores
|
|
Concept
|
Down Syndrome
|
|
Concept
|
Dinitrophenols
|
|
Concept
|
Gestational Age
|
|
Concept
|
Mice, Inbred A
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Neutropenia
|
|
Concept
|
Mice, Inbred AKR
|
|
Concept
|
Cytoplasmic Granules
|
|
Concept
|
Cluster Analysis
|
|
Concept
|
Immunization, Passive
|
|
Concept
|
Immunoglobulin E
|
|
Concept
|
Lipopolysaccharide Receptors
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Models, Animal
|
|
Concept
|
Leukemia, Promyelocytic, Acute
|
|
Concept
|
HL-60 Cells
|
|
Concept
|
Cell Culture Techniques
|
|
Concept
|
Lymphocyte Activation
|
|
Concept
|
Antigens, Viral
|
|
Concept
|
Luciferases
|
|
Concept
|
Endorphins
|
|
Concept
|
Leukocytes, Mononuclear
|
|
Concept
|
Substantia Gelatinosa
|
|
Concept
|
Opsonin Proteins
|
|
Concept
|
Phagocytosis
|
|
Concept
|
Receptors, Cytokine
|
|
Concept
|
K562 Cells
|
|
Concept
|
Carcinoma, Hepatocellular
|
|
Concept
|
Binding Sites
|
|
Concept
|
Antigens, CD34
|
|
Concept
|
Mass Screening
|
|
Concept
|
DNA Probes
|
|
Concept
|
Lymphohistiocytosis, Hemophagocytic
|
|
Concept
|
Abscess
|
|
Concept
|
Interleukin-8
|
|
Concept
|
Lymphoma, Follicular
|
|
Concept
|
Chromosomes, Human, Pair 3
|
|
Concept
|
Pain, Intractable
|
|
Concept
|
Cell Transformation, Neoplastic
|
|
Concept
|
Ubiquitin-Conjugating Enzymes
|
|
Concept
|
Leukemia, Experimental
|
|
Concept
|
Tunicamycin
|
|
Concept
|
Papio
|
|
Concept
|
Prevalence
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
Mutagenesis
|
|
Concept
|
Drosophila Proteins
|
|
Concept
|
Induced Pluripotent Stem Cells
|
|
Concept
|
Eosinophilia
|
|
Concept
|
Periodic Acid-Schiff Reaction
|
|
Concept
|
Toll-Like Receptor 8
|
|
Concept
|
Leukemia, Myeloid, Acute
|
|
Concept
|
Fluorescence
|
|
Concept
|
Microfilament Proteins
|
|
Concept
|
Chromosomes, Human, Pair 21
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Guinea Pigs
|
|
Concept
|
Prospective Studies
|
|
Concept
|
United Kingdom
|
|
Concept
|
Cell Transformation, Viral
|
|
Concept
|
Rats
|
|
Concept
|
Esophageal Stenosis
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Integrin alpha4
|
|
Concept
|
Staining and Labeling
|
|
Concept
|
Spleen
|
|
Concept
|
Codon, Nonsense
|
|
Concept
|
Infant, Newborn
|
|
Concept
|
Oligodeoxyribonucleotides
|
|
Concept
|
Aspergillosis, Allergic Bronchopulmonary
|
|
Concept
|
Sequence Homology, Nucleic Acid
|
|
Concept
|
In Situ Hybridization
|
|
Concept
|
Thymidine
|
|
Concept
|
Chromosome Aberrations
|
|
Concept
|
Macrophage Colony-Stimulating Factor
|
|
Concept
|
Passive Cutaneous Anaphylaxis
|
|
Concept
|
Fibrosis
|
|
Concept
|
Enzyme Inhibitors
|
|
Concept
|
Blood Bactericidal Activity
|
|
Concept
|
Mice, Inbred NZB
|
|
Concept
|
Analgesics
|
|
Concept
|
Chromosome Deletion
|
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
|
Concept
|
B-Lymphocytes
|
|
Concept
|
Point Mutation
|
|
Concept
|
Hemocyanins
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Polymerase Chain Reaction
|
|
Concept
|
Antilymphocyte Serum
|
|
Concept
|
Adaptor Protein Complex 3
|
|
Concept
|
United States
|
|
Concept
|
Ovalbumin
|
|
Concept
|
Hydroxyethyl Starch Derivatives
|
|
Concept
|
Polyploidy
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Perforin
|
|
Concept
|
Annexin A5
|
|
Concept
|
Risk Assessment
|
|
Concept
|
In Situ Hybridization, Fluorescence
|
|
Concept
|
Asthma
|
|
Concept
|
NADPH Dehydrogenase
|
|
Concept
|
Superoxides
|
|
Concept
|
Immunization, Secondary
|
|
Concept
|
Mutation, Missense
|
|
Concept
|
Risk
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Yersinia pestis
|
|
Concept
|
NADPH Oxidases
|
|
Concept
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Promoter Regions, Genetic
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Concept
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Cesium Radioisotopes
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Concept
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Base Sequence
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Concept
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Osteosarcoma
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Concept
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Follow-Up Studies
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Concept
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Hyperplasia
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Concept
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Regulatory Sequences, Ribonucleic Acid
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Concept
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Killer Cells, Natural
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Concept
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Interferon Type I
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Concept
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Gene Knockdown Techniques
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Concept
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Genes, Homeobox
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Concept
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HIV
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Concept
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Immunohistochemistry
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Concept
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Cleft Palate
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Concept
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Mice, Mutant Strains
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Concept
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Frameshift Mutation
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Concept
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Leukapheresis
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Concept
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DNA Transposable Elements
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Concept
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Immunoblotting
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Concept
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Immunologic Memory
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Concept
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Interleukin-3
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Concept
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Africa South of the Sahara
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Concept
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Thrombopoietin
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Concept
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Polysaccharides, Bacterial
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Academic Article
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Comment on: Phenotypic Prenatal Diagnosis of Chronic Granulomatous Disease: A Useful Tool in the Absence of Molecular Diagnosis.
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Academic Article
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Trisomy silencing by XIST normalizes Down syndrome cell pathogenesis demonstrated for hematopoietic defects in vitro.
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Concept
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Rituximab
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Concept
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Loss of Function Mutation
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Concept
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CCCTC-Binding Factor
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Concept
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NADPH Oxidase 2
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Concept
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Neointima
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Concept
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Maltose-Binding Proteins
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Concept
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Antibodies, Monoclonal, Murine-Derived
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Concept
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Real-Time Polymerase Chain Reaction
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Concept
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Chemotherapy-Induced Febrile Neutropenia
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