| Item Type | Name |
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Academic Article
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A molecular basis for how a single TCR interfaces multiple ligands.
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Academic Article
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Direct visualization of cross-reactive effector and memory allo-specific CD8 T cells generated in response to viral infections.
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Academic Article
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Immunogenicity of herpes simplex virus type 1 mutants containing deletions in one or more alpha-genes: ICP4, ICP27, ICP22, and ICP0.
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Academic Article
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Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance.
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Academic Article
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TLR agonists abrogate co-stimulation blockade-induced mixed chimerism and transplantation tolerance.
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Academic Article
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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.
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Academic Article
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Humanized mouse models to study human diseases.
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Academic Article
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Humanized mice for immune system investigation: progress, promise and challenges.
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Academic Article
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Durable knockdown and protection from HIV transmission in humanized mice treated with gel-formulated CD4 aptamer-siRNA chimeras.
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Academic Article
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Preapoptotic phenotype of viral epitope-specific CD8 T cells precludes memory development and is an intrinsic property of the epitope.
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Academic Article
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Rapid production of TNF-alpha following TCR engagement of naive CD8 T cells.
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Academic Article
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TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts.
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Academic Article
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Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help.
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Academic Article
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Transgenic expression of the viral FLIP MC159 causes lpr/gld-like lymphoproliferation and autoimmunity.
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Academic Article
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Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice.
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Academic Article
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TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade.
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Academic Article
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Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.
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Academic Article
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NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection.
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Academic Article
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Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.
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Academic Article
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Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.
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Academic Article
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Maturation-dependent licensing of naive T cells for rapid TNF production.
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Academic Article
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Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice.
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Academic Article
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T-cell activation and transplantation tolerance.
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Academic Article
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Humanized mice as a preclinical tool for infectious disease and biomedical research.
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Academic Article
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Humanized mice for the study of type 1 and type 2 diabetes.
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Academic Article
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Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice.
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Academic Article
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Alloreactive CD8 T cells rescued from apoptosis during co-stimulation blockade by Toll-like receptor stimulation remain susceptible to Fas-induced cell death.
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
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Concept
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Receptors, IgG
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Concept
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Interleukin-2 Receptor alpha Subunit
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Concept
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Receptors, Antigen, T-Cell
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Concept
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Receptor, Interferon alpha-beta
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Concept
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Receptor, Platelet-Derived Growth Factor alpha
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Concept
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Receptors, Interleukin-2
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Concept
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Toll-Like Receptors
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Concept
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Receptors, CCR5
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Concept
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Toll-Like Receptor 4
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Concept
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GTP-Binding Protein alpha Subunits, Gs
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Concept
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Receptors, Tumor Necrosis Factor, Type II
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Concept
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Tumor Necrosis Factor-alpha
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Concept
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Toll-Like Receptor 3
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Concept
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Receptors, Antigen, T-Cell, gamma-delta
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Concept
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Integrin alpha6
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Concept
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alpha 1-Antitrypsin
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Concept
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Receptor, Notch1
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Concept
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Receptors, Interleukin-7
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Concept
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Receptors, Interleukin-12
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Concept
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Receptors, Glucocorticoid
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Concept
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Interleukin Receptor Common gamma Subunit
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Concept
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alpha 1-Antitrypsin Deficiency
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Concept
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Receptors, Immunologic
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Concept
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Receptors, Interleukin
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Concept
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Transient Receptor Potential Channels
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Concept
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fas Receptor
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Academic Article
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Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice.
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Academic Article
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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
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Academic Article
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Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection.
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Academic Article
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Generation of improved humanized mouse models for human infectious diseases.
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Academic Article
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The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.
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Academic Article
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Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice.
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Academic Article
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Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.
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Academic Article
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Genetically modified human CD4(+) T cells can be evaluated in?vivo without lethal graft-versus-host disease.
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Academic Article
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Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
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Academic Article
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Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of a-1 Antitrypsin Deficiency.
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Academic Article
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Cutting Edge: Early Attrition of Memory T Cells during Inflammation and Costimulation Blockade Is Regulated Concurrently by Proapoptotic Proteins Fas and Bim.
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Academic Article
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AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
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Academic Article
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Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features.
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Academic Article
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Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death.
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Concept
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Receptors, Prostaglandin E, EP4 Subtype
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Concept
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Costimulatory and Inhibitory T-Cell Receptors
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Concept
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Programmed Cell Death 1 Receptor
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Academic Article
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Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15.
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Academic Article
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NOD-scid IL2r?null mice lacking TLR4 support human immune system development and the study of human-specific innate immunity.
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Academic Article
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?d T cell dichotomy with opposing cytotoxic and wound healing functions in human solid tumors.
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Academic Article
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CDK4/6 Inhibition Sensitizes Intracranial Tumors to PD-1 Blockade in Preclinical Models of Brain Metastasis.
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Academic Article
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The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin a6 mRNA splicing.
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Academic Article
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The co-receptor Neuropilin-1 enhances proliferation in inv(16) acute myeloid leukemia via VEGF signaling.
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