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One or more keywords matched the following properties of Imbalzano, Anthony
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Academic Background

B.A. (cum laude), University of Pennsylvania, 1986
Ph.D., Harvard University, 1991
Post-doctoral Fellow, Massachusetts General Hospital, 1991-1996
Assistant Professor, Cell Biology, UMass Medical School, 1997-2002
Scholar of the Leukemia and Lymphoma Society, 1999-2004
Associate Professor, Cell Biology, UMass Medical School, 2002 - 2008
Professor, Cell Biology, UMass Medical School, 2008-2016
Professor, Biochemistry & Mol. Pharmacology, UMass Medical School, 2017-

Research

Mammalian SWI/SNF Chromatin Remodeling Enzymes Promote Cell Differentiation
http://www.umassmed.edu/imbalzanolab/research/mammalian-swisnf-enzymes-promote-cell-differentiation/

Mammalian SWI/SNF Chromatin Remodeling Enzymes as Drivers of Cancer
http://www.umassmed.edu/imbalzanolab/research/mammalian-swisnf-enzymes-as-drivers-of-cancer/

Laboratory Personnel

Current Personnel
http://www.umassmed.edu/imbalzanolab/lab-members/current-lab-members/

Previous Trainees
http://www.umassmed.edu/imbalzanolab/lab-members/alumni/

One or more keywords matched the following items that are connected to Imbalzano, Anthony
Item TypeName
Academic Article RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling.
Academic Article Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes.
Academic Article Phosphorylation of linker histones regulates ATP-dependent chromatin remodeling enzymes.
Academic Article The myogenic basic helix-loop-helix family of transcription factors shows similar requirements for SWI/SNF chromatin remodeling enzymes during muscle differentiation in culture.
Academic Article p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci.
Academic Article Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme.
Academic Article MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex.
Academic Article Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes.
Academic Article HMGN1 is dispensable for myogenesis and adipogenesis.
Academic Article Functional delineation of three groups of the ATP-dependent family of chromatin remodeling enzymes.
Academic Article Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.
Academic Article Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter.
Academic Article SWI/SNF chromatin remodeling ATPase Brm regulates the differentiation of early retinal stem cells/progenitors by influencing Brn3b expression and Notch signaling.
Academic Article The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.
Academic Article Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function.
Academic Article Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments.
Academic Article An improved restriction enzyme accessibility assay for analyzing changes in chromatin structure in samples of limited cell number.
Academic Article Nuclear shape changes are induced by knockdown of the SWI/SNF ATPase BRG1 and are independent of cytoskeletal connections.
Academic Article Functional properties of ATP-dependent chromatin remodeling enzymes.
Academic Article Temporal recruitment of transcription factors and SWI/SNF chromatin-remodeling enzymes during adipogenic induction of the peroxisome proliferator-activated receptor gamma nuclear hormone receptor.
Academic Article SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation.
Academic Article Snf5 tumor suppressor couples chromatin remodeling, checkpoint control, and chromosomal stability.
Academic Article Effects of HMGN1 on chromatin structure and SWI/SNF-mediated chromatin remodeling.
Academic Article Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.
Academic Article Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers.
Academic Article Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity.
Academic Article The protein arginine methyltransferase Prmt5 is required for myogenesis because it facilitates ATP-dependent chromatin remodeling.
Academic Article Interaction of papillomavirus E2 protein with the Brm chromatin remodeling complex leads to enhanced transcriptional activation.
Academic Article The Chd family of chromatin remodelers.
Academic Article A mutation in the mouse Chd2 chromatin remodeling enzyme results in a complex renal phenotype.
Academic Article Induction of TLR4-target genes entails calcium/calmodulin-dependent regulation of chromatin remodeling.
Academic Article Distinct protein arginine methyltransferases promote ATP-dependent chromatin remodeling function at different stages of skeletal muscle differentiation.
Academic Article The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression.
Academic Article SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.
Academic Article SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.
Academic Article Protein arginine methyltransferase 5 (Prmt5) promotes gene expression of peroxisome proliferator-activated receptor ?2 (PPAR?2) and its target genes during adipogenesis.
Concept Chromatin Assembly and Disassembly
Academic Article BRG1, a SWI/SNF chromatin remodeling enzyme ATPase, is required for maintenance of nuclear shape and integrity.
Academic Article Contrasting roles for MyoD in organizing myogenic promoter structures during embryonic skeletal muscle development.
Academic Article Spatial re-organization of myogenic regulatory sequences temporally controls gene expression.
Academic Article Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme.
Academic Article The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.
Academic Article Brg1 Controls the Expression of Pax7 to Promote Viability and Proliferation of Mouse Primary Myoblasts.
Academic Article Promoter-enhancer looping at the PPAR?2 locus during adipogenic differentiation requires the Prmt5 methyltransferase.
Academic Article Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells.
Academic Article SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells.
Academic Article The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation.
Academic Article Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer.
Academic Article The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer.
Academic Article Temporal regulation of chromatin during myoblast differentiation.
Academic Article Calcineurin Broadly Regulates the Initiation of Skeletal Muscle-Specific Gene Expression by Binding Target Promoters and Facilitating the Interaction of the SWI/SNF Chromatin Remodeling Enzyme.
Academic Article CK2-Dependent Phosphorylation of the Brg1 Chromatin Remodeling Enzyme Occurs during Mitosis.
Academic Article Regulation of the Mammalian SWI/SNF Family of Chromatin Remodeling Enzymes by Phosphorylation during Myogenesis.
Academic Article The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.
Academic Article Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast cell cycle progression and expression of the Pax7 regulator.
Academic Article Differential Contributions of mSWI/SNF Chromatin Remodeler Sub-Families to Myoblast Differentiation.
Search Criteria
  • Chromatin Assembly and Disassembly