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Therapeutic targeting of C-terminal binding protein in human cancer.
Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.
Structure-guided design of a high affinity inhibitor to human CtBP.
Assembly of human C-terminal binding protein (CtBP) into tetramers.
Cryo-EM structure of CtBP2 confirms tetrameric architecture.
NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).