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Schiffer, Celia
One or more keywords matched the following items that are connected to
Schiffer, Celia
Item Type
Name
Academic Article
Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site.
Academic Article
Contribution of Ser386 and Ser396 to activation of interferon regulatory factor 3.
Academic Article
Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
Academic Article
Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces.
Academic Article
The effect of clade-specific sequence polymorphisms on HIV-1 protease activity and inhibitor resistance pathways.
Academic Article
Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones.
Academic Article
Dynamics of preferential substrate recognition in HIV-1 protease: redefining the substrate envelope.
Academic Article
Nitric oxide-mediated inhibition of Hdm2-p53 binding.
Academic Article
Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments.
Academic Article
Covariation of amino acid positions in HIV-1 protease.
Academic Article
Simultaneous refinement of the structure of BPTI against NMR data measured in solution and X-ray diffraction data measured in single crystals.
Academic Article
Exploring the role of the solvent in the denaturation of a protein: a molecular dynamics study of the DNA binding domain of the 434 repressor.
Academic Article
Expression, purification, and characterization of thymidylate synthase from Lactococcus lactis.
Academic Article
Substrate specificity in HIV-1 protease by a biased sequence search method.
Academic Article
N88D facilitates the co-occurrence of D30N and L90M and the development of multidrug resistance in HIV type 1 protease following nelfinavir treatment failure.
Academic Article
Structural analysis of human immunodeficiency virus type 1 CRF01_AE protease in complex with the substrate p1-p6.
Academic Article
Human immunodeficiency virus type 1 protease-correlated cleavage site mutations enhance inhibitor resistance.
Academic Article
TMC310911, a novel human immunodeficiency virus type 1 protease inhibitor, shows in vitro an improved resistance profile and higher genetic barrier to resistance compared with current protease inhibitors.
Concept
Molecular Sequence Data
Academic Article
A novel Geobacteraceae-specific outer membrane protein J (OmpJ) is essential for electron transport to Fe(III) and Mn(IV) oxides in Geobacter sulfurreducens.
Academic Article
Investigation of protein unfolding and stability by computer simulation.
Search Criteria
Molecular Sequence Data