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Search Results to Celia A Schiffer PhD

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One or more keywords matched the following items that are connected to Schiffer, Celia

Item TypeName
Academic Article Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site.
Academic Article Contribution of Ser386 and Ser396 to activation of interferon regulatory factor 3.
Academic Article Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
Academic Article Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces.
Academic Article The effect of clade-specific sequence polymorphisms on HIV-1 protease activity and inhibitor resistance pathways.
Academic Article Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones.
Academic Article Dynamics of preferential substrate recognition in HIV-1 protease: redefining the substrate envelope.
Academic Article Nitric oxide-mediated inhibition of Hdm2-p53 binding.
Academic Article Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments.
Academic Article Covariation of amino acid positions in HIV-1 protease.
Academic Article Simultaneous refinement of the structure of BPTI against NMR data measured in solution and X-ray diffraction data measured in single crystals.
Academic Article Exploring the role of the solvent in the denaturation of a protein: a molecular dynamics study of the DNA binding domain of the 434 repressor.
Academic Article Expression, purification, and characterization of thymidylate synthase from Lactococcus lactis.
Academic Article Substrate specificity in HIV-1 protease by a biased sequence search method.
Academic Article N88D facilitates the co-occurrence of D30N and L90M and the development of multidrug resistance in HIV type 1 protease following nelfinavir treatment failure.
Academic Article Structural analysis of human immunodeficiency virus type 1 CRF01_AE protease in complex with the substrate p1-p6.
Academic Article Human immunodeficiency virus type 1 protease-correlated cleavage site mutations enhance inhibitor resistance.
Academic Article TMC310911, a novel human immunodeficiency virus type 1 protease inhibitor, shows in vitro an improved resistance profile and higher genetic barrier to resistance compared with current protease inhibitors.
Concept Molecular Sequence Data
Academic Article A novel Geobacteraceae-specific outer membrane protein J (OmpJ) is essential for electron transport to Fe(III) and Mn(IV) oxides in Geobacter sulfurreducens.
Academic Article Investigation of protein unfolding and stability by computer simulation.

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  • Molecular Sequence Data