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Wolfe, Scot

One or more keywords matched the following items that are connected to Wolfe, Scot

Item Type	Name
Academic Article	Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases.
Academic Article	Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells.
Academic Article	DNA-binding-domain fusions enhance the targeting range and precision of Cas9.
Academic Article	Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.
Academic Article	Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing.
Academic Article	Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice.
Concept	HEK293 Cells
Academic Article	Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors.
Academic Article	Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets.

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HEK293 Cells