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Wolfe, Scot

One or more keywords matched the following items that are connected to Wolfe, Scot

Item Type	Name
Concept	RNA, Guide
Academic Article	DNA-binding-domain fusions enhance the targeting range and precision of Cas9.
Academic Article	Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
Academic Article	Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.
Academic Article	Enhanced Cas12a editing in mammalian cells and zebrafish.
Academic Article	Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases.
Academic Article	Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Academic Article	Genome editing of HBG1 and HBG2 to induce fetal hemoglobin.
Academic Article	Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice.
Academic Article	CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease.
Academic Article	Genome-wide detection of CRISPR editing in vivo using GUIDE-tag.
Academic Article	Human genetic diversity alters off-target outcomes of therapeutic gene editing.

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RNA Guide