| Item Type | Name |
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Academic Article
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Structural basis of activation and GTP hydrolysis in Rab proteins.
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Academic Article
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A helical turn motif in Mss4 is a critical determinant of Rab binding and nucleotide release.
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Academic Article
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Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition.
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Academic Article
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Sequential roles for phosphatidylinositol 3-phosphate and Rab5 in tethering and fusion of early endosomes via their interaction with EEA1.
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Academic Article
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Multivalent endosome targeting by homodimeric EEA1.
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Academic Article
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Determinants of the broad recognition of exocytic Rab GTPases by Mss4.
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Academic Article
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Gs alpha meets its target--shedding light on a key signal transduction event.
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Academic Article
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Signal transduction. MAP kinase signaling specificity.
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Academic Article
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Essential role of Ca2+/calmodulin in Early Endosome Antigen-1 localization.
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Academic Article
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Membrane recognition and targeting by lipid-binding domains.
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Academic Article
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The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization.
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Academic Article
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Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
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Academic Article
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ESCRT complexes assembled and GLUEd.
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Academic Article
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Membrane and juxtamembrane targeting by PH and PTB domains.
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Academic Article
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TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.
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Academic Article
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Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.
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Academic Article
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Structural basis for Rab GTPase activation by VPS9 domain exchange factors.
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Academic Article
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Legionella pneumophila proteins that regulate Rab1 membrane cycling.
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Academic Article
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Calculating the potential of C2 domains for membrane binding.
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Academic Article
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TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans.
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Academic Article
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Rab GEFs and GAPs.
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Academic Article
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RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
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Academic Article
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Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis.
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Academic Article
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RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36.
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Academic Article
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TBC1D13 is a RAB35 specific GAP that plays an important role in GLUT4 trafficking in adipocytes.
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Academic Article
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The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes.
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Academic Article
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Determinants of Rab5 interaction with the N terminus of early endosome antigen 1.
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Academic Article
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Germline mutations affecting G?11 in hypoparathyroidism.
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Academic Article
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Association-dissociation modulation of enzyme activity: case of lactose synthase.
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Academic Article
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Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5.
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Academic Article
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The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor.
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Academic Article
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ART2, a T cell surface mono-ADP-ribosyltransferase, generates extracellular poly(ADP-ribose).
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Academic Article
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An endocytic pathway as a target of tubby for regulation of fat storage.
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Academic Article
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TBC1D20 is a Rab1 GTPase-activating protein that mediates hepatitis C virus replication.
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Academic Article
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Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes.
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Academic Article
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Structural mechanisms for regulation of membrane traffic by rab GTPases.
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Academic Article
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Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1).
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Academic Article
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Electrostatic interactions in wild-type and mutant recombinant human myoglobins.
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Academic Article
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The Legionella pneumophila GTPase activating protein LepB accelerates Rab1 deactivation by a non-canonical hydrolytic mechanism.
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Academic Article
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Lactose synthase: effect of alpha-lactalbumin on substrate activity of N-acylglucosamines.
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Academic Article
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Anatomy and dynamics of a ligand-binding pathway in myoglobin: the roles of residues 45, 60, 64, and 68.
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Concept
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Vesicular Transport Proteins
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Concept
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rab4 GTP-Binding Proteins
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Concept
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Protein Binding
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Concept
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DNA-Binding Proteins
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Concept
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GTP-Binding Proteins
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Concept
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Carrier Proteins
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Concept
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rab1 GTP-Binding Proteins
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Concept
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GTP-Binding Protein alpha Subunits, Gs
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Concept
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Monomeric GTP-Binding Proteins
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Concept
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rab3A GTP-Binding Protein
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Concept
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rab GTP-Binding Proteins
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Concept
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rab3 GTP-Binding Proteins
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Concept
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Calcium-Binding Proteins
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Concept
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rab5 GTP-Binding Proteins
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Concept
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GTP-Binding Protein alpha Subunits
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Academic Article
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The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins.
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Academic Article
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Molecular insights into Rab7-mediated endosomal recruitment of core retromer: deciphering the role of Vps26 and Vps35.
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Academic Article
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Single point mutation in Rabenosyn-5 in a female with intractable seizures and evidence of defective endocytotic trafficking.
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Academic Article
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High-throughput assay for profiling the substrate specificity of Rab GTPase-activating proteins.
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Academic Article
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A PH Domain with Dual Phospholipid Binding Sites Regulates the ARF GAP, ASAP1.
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Academic Article
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Membrane Trafficking: An Endosome Tether Meets a Rab and Collapses.
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Academic Article
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Special Issue: GTPases in trafficking, autophagy, and disease (FASEB SRC).
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Academic Article
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Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors.
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Academic Article
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Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes.
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Academic Article
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X Caps the Phosphate for Phospho-Rab GTPase Recognition in Ciliogenesis and Parkinson's Disease.
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Academic Article
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Propelling COPII vesicle biogenesis at the endoplasmic reticulum.
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Academic Article
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High-Throughput Assay for Profiling the Substrate Specificity of Rab GTPase-Activating Proteins.
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Academic Article
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Systems-level effects of allosteric perturbations to a model molecular switch.
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