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Lambright, David

One or more keywords matched the following items that are connected to Lambright, David

Item Type	Name
Academic Article	Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
Academic Article	The 2.0 A crystal structure of a heterotrimeric G protein.
Academic Article	Structural basis of activation and GTP hydrolysis in Rab proteins.
Academic Article	Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition.
Academic Article	Multivalent endosome targeting by homodimeric EEA1.
Academic Article	Gs alpha meets its target--shedding light on a key signal transduction event.
Academic Article	Signal transduction. MAP kinase signaling specificity.
Academic Article	Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Academic Article	ESCRT complexes assembled and GLUEd.
Academic Article	Membrane and juxtamembrane targeting by PH and PTB domains.
Academic Article	TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.
Academic Article	Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains.
Academic Article	Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.
Academic Article	The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes.
Academic Article	Germline mutations affecting Ga11 in hypoparathyroidism.
Academic Article	Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5.
Academic Article	ART2, a T cell surface mono-ADP-ribosyltransferase, generates extracellular poly(ADP-ribose).
Academic Article	Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes.
Academic Article	Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors.
Academic Article	Structural mechanisms for regulation of membrane traffic by rab GTPases.
Academic Article	Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1).
Academic Article	The Legionella pneumophila GTPase activating protein LepB accelerates Rab1 deactivation by a non-canonical hydrolytic mechanism.
Academic Article	Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors.
Concept	Models, Molecular
Academic Article	Structural basis for PI(4)P-specific membrane recruitment of the Legionella pneumophila effector DrrA/SidM.
Academic Article	Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase ? and regulates complex V activity.
Academic Article	A PH Domain with Dual Phospholipid Binding Sites Regulates the ARF GAP, ASAP1.
Academic Article	Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes.
Academic Article	Systems-level effects of allosteric perturbations to a model molecular switch.

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Models Molecular