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Lambright, David
One or more keywords matched the following items that are connected to
Lambright, David
Item Type
Name
Academic Article
Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
Academic Article
The 2.0 A crystal structure of a heterotrimeric G protein.
Academic Article
A helical turn motif in Mss4 is a critical determinant of Rab binding and nucleotide release.
Academic Article
Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition.
Academic Article
Sequential roles for phosphatidylinositol 3-phosphate and Rab5 in tethering and fusion of early endosomes via their interaction with EEA1.
Academic Article
Multivalent endosome targeting by homodimeric EEA1.
Academic Article
Determinants of the broad recognition of exocytic Rab GTPases by Mss4.
Academic Article
Structural basis for endosomal targeting by FYVE domains.
Academic Article
Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains.
Academic Article
The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization.
Academic Article
Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Academic Article
Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains.
Academic Article
Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.
Academic Article
TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans.
Academic Article
RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
Academic Article
RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36.
Academic Article
The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes.
Academic Article
Determinants of Rab5 interaction with the N terminus of early endosome antigen 1.
Academic Article
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.
Academic Article
Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5.
Academic Article
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis.
Academic Article
Evolutionarily conserved structural and functional roles of the FYVE domain.
Academic Article
Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors.
Academic Article
Specificity and membrane partitioning of Grsp1 signaling complexes with Grp1 family Arf exchange factors.
Academic Article
Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1).
Academic Article
The Legionella pneumophila GTPase activating protein LepB accelerates Rab1 deactivation by a non-canonical hydrolytic mechanism.
Concept
Molecular Sequence Data
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Molecular Sequence Data