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One or more keywords matched the following items that are connected to Stavnezer, Janet
Item TypeName
Academic Article Antibody class switching.
Academic Article The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins.
Academic Article Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter.
Academic Article Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes.
Academic Article The mu switch region tandem repeats are important, but not required, for antibody class switch recombination.
Academic Article Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice.
Academic Article Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions.
Academic Article Inducible DNA breaks in Ig S regions are dependent on AID and UNG.
Academic Article Copy choice mechanism of immunoglobulin heavy-chain switch recombination.
Academic Article The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA.
Academic Article Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b.
Academic Article Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair.
Academic Article APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.
Academic Article The roles of APE1, APE2, DNA polymerase beta and mismatch repair in creating S region DNA breaks during antibody class switch.
Academic Article Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching.
Academic Article Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats.
Academic Article Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.
Academic Article A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation.
Academic Article Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes.
Academic Article Complex regulation and function of activation-induced cytidine deaminase.
Academic Article AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].
Academic Article The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells.
Academic Article Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
Academic Article Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer.
Academic Article Mlh1 can function in antibody class switch recombination independently of Msh2.
Academic Article The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2.
Academic Article Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination.
Academic Article Regulation of antibody production and class switching by TGF-beta.
Academic Article Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50.
Academic Article Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching.
Academic Article Antibody class switching: uncoupling S region accessibility from transcription.
Academic Article Evolution of isotype switching.
Academic Article Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination.
Academic Article Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2.
Academic Article Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination.
Academic Article Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells.
Academic Article DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination.
Academic Article Mechanism and regulation of class switch recombination.
Academic Article The surprising discovery that TGF beta specifically induces the IgA class switch.
Academic Article p53 represses class switch recombination to IgG2a through its antioxidant function.
Academic Article Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching.
Academic Article Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells.
Academic Article Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch.
Concept Immunoglobulin Allotypes
Concept Immunoglobulin epsilon-Chains
Concept Immunoglobulin Variable Region
Concept Somatic Hypermutation, Immunoglobulin
Concept Immunoglobulin alpha-Chains
Concept Genes, Immunoglobulin
Concept Immunoglobulin gamma-Chains
Concept Immunoglobulin M
Concept Immunoglobulin G
Concept Immunoglobulin A
Concept Immunoglobulin Switch Region
Concept Immunoglobulin E
Concept Immunoglobulin Heavy Chains
Concept Immunoglobulin Isotypes
Concept Immunoglobulin Idiotypes
Concept Immunoglobulin Constant Regions
Concept Immunoglobulin Class Switching
Concept Immunoglobulin mu-Chains
Academic Article DNA polymerases ? and ? do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.
Academic Article A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination.
Academic Article Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation.
Academic Article IgH chain class switch recombination: mechanism and regulation.
Academic Article Response to comment on "IgH chain class switch recombination: mechanism and regulation".
Academic Article Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.
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  • Immunoglobulin Variable Region