| Item Type | Name |
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Academic Article
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Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats.
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Academic Article
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The rat T-cell surface protein RT6 is associated with src family tyrosine kinases and generates an activation signal.
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Academic Article
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Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.
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Academic Article
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Blockade of CD40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance.
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Academic Article
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CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment.
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Academic Article
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Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells.
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Academic Article
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Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD-scid mice.
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Academic Article
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TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat.
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Academic Article
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Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research.
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Academic Article
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BB rat thymocytes cultured in the presence of islets lose their ability to transfer autoimmune diabetes.
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Academic Article
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Creation of "humanized" mice to study human immunity.
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Academic Article
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Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.
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Academic Article
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An atypical population of NK cells that spontaneously secrete IFN-gamma and IL-4 is present in the intraepithelial lymphoid compartment of the rat.
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Academic Article
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Depletion of the programmed death-1 receptor completely reverses established clonal anergy in CD4(+) T lymphocytes via an interleukin-2-dependent mechanism.
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Academic Article
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Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.
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Academic Article
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Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.
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Academic Article
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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.
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Academic Article
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Humanized mouse models to study human diseases.
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Academic Article
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T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7.
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Academic Article
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Thioredoxin-interacting protein mediates ER stress-induced ? cell death through initiation of the inflammasome.
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Academic Article
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A420983, a novel, small molecule inhibitor of LCK prevents allograft rejection.
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Academic Article
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Humanized mice for immune system investigation: progress, promise and challenges.
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Academic Article
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Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures.
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Academic Article
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Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations.
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Academic Article
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Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice.
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Academic Article
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Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells.
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Academic Article
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Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning.
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Academic Article
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Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice.
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Academic Article
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Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.
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Academic Article
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Deficiencies in gut NK cell number and function precede diabetes onset in BB rats.
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Academic Article
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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.
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Academic Article
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TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts.
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Academic Article
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A regulatory CD4+ T cell subset in the BB rat model of autoimmune diabetes expresses neither CD25 nor Foxp3.
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Academic Article
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A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.
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Academic Article
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Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response.
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Academic Article
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Humanized SCID mouse models for biomedical research.
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Academic Article
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A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.
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Academic Article
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Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice.
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Academic Article
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Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat.
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Academic Article
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Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.
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Academic Article
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NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection.
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Academic Article
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Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.
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Academic Article
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Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.
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Academic Article
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The role of JNK in the development of hepatocellular carcinoma.
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Academic Article
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Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice.
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Academic Article
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Humanized mice as a preclinical tool for infectious disease and biomedical research.
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Academic Article
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Humanized mice for the study of type 1 and type 2 diabetes.
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Academic Article
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Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice.
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Academic Article
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Alloreactive CD8 T cells rescued from apoptosis during co-stimulation blockade by Toll-like receptor stimulation remain susceptible to Fas-induced cell death.
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Academic Article
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High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors.
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Concept
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Interleukin-2 Receptor alpha Subunit
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Concept
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Interleukin-15
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Concept
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Receptors, Interleukin-2
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Concept
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Interleukin-11
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Concept
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Interleukin-7
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Concept
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Interleukin-2
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Concept
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Interleukin-1
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Concept
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Receptors, Interleukin-7
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Concept
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Receptors, Interleukin-12
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Concept
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Interleukin-1beta
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Concept
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Interleukin-12 Subunit p40
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Concept
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Interleukin-4
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Concept
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Interleukin Receptor Common gamma Subunit
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Concept
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Interleukin-6
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Concept
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Receptors, Interleukin
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Concept
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Interleukin-18
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Concept
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Interleukin-12
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Concept
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Interleukin-3
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Academic Article
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Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice.
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Academic Article
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NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.
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Academic Article
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Generation of improved humanized mouse models for human infectious diseases.
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Academic Article
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Generation of ? cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.
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Academic Article
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Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets.
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Academic Article
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The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.
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Academic Article
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Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.
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Academic Article
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Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.
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Academic Article
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Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features.
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Academic Article
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Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15.
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Academic Article
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IFN?-IL12 axis regulates intercellular crosstalk in metabolic dysfunction-associated steatotic liver disease.
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