| Item Type | Name |
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Academic Article
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Lack of peripherally induced tolerance to established skin allografts in immunologically reconstituted scid mice.
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Academic Article
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Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice.
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Academic Article
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Tolerance to islet xenografts induced by dual manipulation of antigen presentation and co-stimulation.
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Academic Article
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Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients.
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Academic Article
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Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice.
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Academic Article
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CD8+ T lymphocytes are not required for murine resistance to human filarial parasites.
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Academic Article
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Induction of immunological tolerance to islet allografts.
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Academic Article
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Prolonged skin allograft survival in mice treated with Flt3-ligand-induced dendritic cells and anti-CD154 monoclonal antibody.
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Academic Article
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Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease.
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Academic Article
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NOD mice have a generalized defect in their response to transplantation tolerance induction.
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Academic Article
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Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner.
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Academic Article
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Virus-induced abrogation of transplantation tolerance induced by donor-specific transfusion and anti-CD154 antibody.
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Academic Article
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Growth of the human filarial parasite Brugia malayi in mice lacking major histocompatibility complex class II antigen expression.
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Academic Article
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Regulation of human cell engraftment and development of EBV-related lymphoproliferative disorders in Hu-PBL-scid mice.
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Academic Article
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Viral infection abrogates CD8(+) T-cell deletion induced by costimulation blockade.
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Academic Article
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Thymic involution in viable motheaten (me(v)) mice is associated with a loss of intrathymic precursor activity.
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Academic Article
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Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay.
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Academic Article
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Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand.
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Academic Article
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Expression in BALB/c and C57BL/6 mice of Rt6-1 and Rt6-2 ADP-ribosyltransferases that differ in enzymatic activity: C57BL/6 Rt6-1 is a natural transferase knockout.
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Academic Article
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Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.
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Academic Article
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Prolonged survival of rat islet and skin xenografts in mice treated with donor splenocytes and anti-CD154 monoclonal antibody.
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Academic Article
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Improved skin allograft tolerance induced by treatment with donor splenocytes and an extended course of anti-CD154 monoclonal antibody.
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Academic Article
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NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction.
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Academic Article
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Blockade of CD40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance.
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Academic Article
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Direct visualization of cross-reactive effector and memory allo-specific CD8 T cells generated in response to viral infections.
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Academic Article
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Genetic separation of the transplantation tolerance and autoimmune phenotypes in NOD mice.
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Academic Article
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Islet cell autoimmunity and transplantation tolerance: two distinct mechanisms?
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Academic Article
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CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment.
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Academic Article
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Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3.
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Academic Article
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Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms.
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Academic Article
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Insulin dependent diabetes mellitus hypothesis of autoimmunity.
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Academic Article
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Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells.
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Academic Article
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Evaluation of donor-specific transfusion sources: unique failure of bone marrow cells to induce prolonged skin allograft survival with anti-CD154 monoclonal antibody.
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Academic Article
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Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes.
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Academic Article
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NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells.
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Academic Article
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Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/Lt mice.
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Academic Article
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Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD-scid mice.
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Academic Article
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beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function.
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Academic Article
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Evidence for elevated prothymocyte activity in the bone marrow of New Zealand Black (NZB) mice. Elevated prothymocyte activity in NZB mice.
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Academic Article
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Rat xenograft survival in mice treated with donor-specific transfusion and anti-CD154 antibody is enhanced by elimination of host CD4+ cells.
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Academic Article
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Costimulatory blockade induces hyporesponsiveness in T cells that recognize alloantigen via indirect antigen presentation.
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Academic Article
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Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression.
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Academic Article
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Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research.
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Academic Article
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Different mechanisms control peripheral and central tolerance in hematopoietic chimeric mice.
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Academic Article
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Tuberculosis susceptibility of diabetic mice.
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Academic Article
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Creation of "humanized" mice to study human immunity.
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Academic Article
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Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.
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Academic Article
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Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice.
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Academic Article
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Depletion of the programmed death-1 receptor completely reverses established clonal anergy in CD4(+) T lymphocytes via an interleukin-2-dependent mechanism.
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Academic Article
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Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.
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Academic Article
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Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.
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Academic Article
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AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
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Academic Article
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Skin allograft maintenance in a new synchimeric model system of tolerance.
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Academic Article
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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.
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Academic Article
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Islet cell transplantation tolerance.
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Academic Article
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T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7.
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Academic Article
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Cardioprotection with postconditioning: loss of efficacy in murine models of type-2 and type-1 diabetes.
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Academic Article
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Prevention of "Humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach.
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Academic Article
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Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model.
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Academic Article
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Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers.
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Academic Article
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Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r? null mice is enhanced by transgenic expression of membrane-bound human SCF.
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Academic Article
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Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice.
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Academic Article
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Viral abrogation of stem cell transplantation tolerance causes graft rejection and host death by different mechanisms.
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Academic Article
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A420983, a novel, small molecule inhibitor of LCK prevents allograft rejection.
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Academic Article
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GLI1 regulates a novel neuropilin-2/a6?1 integrin based autocrine pathway that contributes to breast cancer initiation.
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Academic Article
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Durable knockdown and protection from HIV transmission in humanized mice treated with gel-formulated CD4 aptamer-siRNA chimeras.
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Academic Article
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Animal models of Sj?gren's syndrome.
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Academic Article
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Defective lymphopoiesis in bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. I. Analysis of development of prothymocytes, early B lineage cells, and terminal deoxynucleotidyl transferase-positive cells.
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Academic Article
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Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice.
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Academic Article
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Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells.
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Academic Article
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Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning.
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Academic Article
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Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice.
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Academic Article
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NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment.
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Academic Article
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High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice.
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Academic Article
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Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells.
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Academic Article
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CD4+ T-lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi.
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Academic Article
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Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.
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Academic Article
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Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody.
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Academic Article
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Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice.
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Academic Article
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Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice.
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Academic Article
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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.
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Academic Article
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TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts.
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Academic Article
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Anti-mouse CD154 antibody treatment facilitates generation of mixed xenogeneic rat hematopoietic chimerism, prevents wasting disease and prolongs xenograft survival in mice.
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Academic Article
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Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice.
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Academic Article
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Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity.
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Academic Article
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Determinants of memory in experimental filarial infections in mice.
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Academic Article
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A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.
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Academic Article
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Humanized SCID mouse models for biomedical research.
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Academic Article
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A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.
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Academic Article
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Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice.
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Academic Article
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T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice.
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Academic Article
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Human BLyS facilitates engraftment of human PBL derived B cells in immunodeficient mice.
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Academic Article
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TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade.
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Academic Article
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Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat.
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Academic Article
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Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.
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Academic Article
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NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection.
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Academic Article
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Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.
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Academic Article
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A novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cells.
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Academic Article
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Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.
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Academic Article
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Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish.
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Academic Article
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Maturation-dependent licensing of naive T cells for rapid TNF production.
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Academic Article
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The role of JNK in the development of hepatocellular carcinoma.
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Academic Article
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Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice.
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Academic Article
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Humanized mice as a preclinical tool for infectious disease and biomedical research.
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Academic Article
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Humanized mice for the study of type 1 and type 2 diabetes.
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Academic Article
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Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice.
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Academic Article
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Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice.
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Academic Article
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Alloreactive CD8 T cells rescued from apoptosis during co-stimulation blockade by Toll-like receptor stimulation remain susceptible to Fas-induced cell death.
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Academic Article
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Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming.
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Academic Article
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Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. III. Normal mouse bone marrow cells enable mev/mev prothymocytes to generate thymocytes after intravenous transfer.
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Academic Article
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Developmental abnormalities of terminal deoxynucleotidyl transferase positive bone marrow cells and thymocytes in New Zealand mice: effects of prostaglandin E1.
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Academic Article
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Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand.
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Academic Article
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Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice.
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Academic Article
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B lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi.
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Academic Article
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A selective culture system for generating terminal deoxynucleotidyl transferase-positive lymphoid precursor cells in vitro. IV. Properties and developmental relationships of the lymphoid cells in the adherent and nonadherent compartments of the culture.
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Academic Article
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Human autoimmune diabetes mellitus: lessons from BB rats and NOD mice--Caveat emptor.
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Academic Article
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Localization of prothymocytes from wild-type and viable motheaten mice following intravenous injection into irradiated adoptive recipients.
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Academic Article
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Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes.
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Academic Article
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Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant.
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Concept
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Mice, Inbred CBA
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C3H
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Concept
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Mice, Inbred ICR
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Inbred NOD
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Concept
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Mice, Inbred Strains
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Concept
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Mice, Inbred NZB
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Concept
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Mice, Inbred DBA
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Academic Article
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CD28 and ITK signals regulate autoreactive T cell trafficking.
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Academic Article
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Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice.
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Academic Article
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Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes.
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Academic Article
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NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.
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Academic Article
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GABA promotes human ?-cell proliferation and modulates glucose homeostasis.
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Academic Article
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Generation of ? cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.
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Academic Article
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Extensive double humanization of both liver and hematopoiesis in FRGN mice.
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Academic Article
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Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates.
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Academic Article
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The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.
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Academic Article
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Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.
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Academic Article
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P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer.
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Academic Article
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Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.
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Academic Article
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Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.
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Academic Article
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Genetically modified human CD4(+) T cells can be evaluated in?vivo without lethal graft-versus-host disease.
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Academic Article
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Frontline Science: Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation.
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Academic Article
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Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I.
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Academic Article
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A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo.
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Academic Article
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mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors.
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Academic Article
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Age-dependent human ? cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
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Academic Article
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Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression.
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Academic Article
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Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
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Academic Article
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Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic ? Cells for In?Vitro and In?Vivo Analysis.
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Academic Article
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Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of a-1 Antitrypsin Deficiency.
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Academic Article
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Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1.
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Academic Article
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Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features.
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Academic Article
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Dapagliflozin Does Not Directly Affect Human a or ? Cells.
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Academic Article
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A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome.
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Academic Article
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Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy.
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Academic Article
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Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15.
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Academic Article
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I-Ag7 ?56/57 polymorphisms regulate non-cognate negative selection to CD4+ T cell orchestrators of type 1 diabetes.
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Academic Article
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NOD-scid IL2r?null mice lacking TLR4 support human immune system development and the study of human-specific innate immunity.
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Academic Article
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Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model.
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Academic Article
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Human insulin as both antigen and protector in type 1 diabetes.
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Academic Article
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IFN?-IL12 axis regulates intercellular crosstalk in metabolic dysfunction-associated steatotic liver disease.
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Academic Article
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Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
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