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Rat RT6.2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity.
The rat T-cell surface protein RT6 is associated with src family tyrosine kinases and generates an activation signal.
Thymic expression of insulin-related genes in an animal model of autoimmune type 1 diabetes.
Ian4 is required for mitochondrial integrity and T cell survival.
Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat.
Mechanisms of allograft prolongation in RT6 T cell-depleted rats.
Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6.
Intrinsic cytotoxicity of natural killer cells to pancreatic islets in vitro.
Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations.
Absence of RT6+ T cells in diabetes-prone biobreeding/Worcester rats is due to genetic and cell developmental defects.
Absence of the RT-6 T cell subset in diabetes-prone BB/W rats.
Prothymocyte development in diabetes-prone BB rats: description of a defect that predisposes to immune abnormalities.
Characterization of RT6-bearing rat lymphocytes. II. Developmental relationships of RT6- and RT6+ T cells.
Characterization of monoclonal antibodies that define rat T cell alloantigens.
Evidence that intrathymic islet transplantation does not prevent diabetes or subsequent islet graft destruction in RT6-depleted, diabetes-resistant BioBreeding/Worcester rats.
Deficiencies in gut NK cell number and function precede diabetes onset in BB rats.
Biochemical studies of RT6 alloantigens in BB/Wor and normal rats. Evidence for intact unexpressed RT6a structural gene in diabetes-prone BB rats.
Depletion of RT6+ T lymphocytes prolongs skin allograft in rats.
High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors.
Rats, Inbred WF
Rats Inbred WF