Item Type | Name |
Academic Article
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The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly.
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Academic Article
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LC2, the chlamydomonas homologue of the t complex-encoded protein Tctex2, is essential for outer dynein arm assembly.
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Academic Article
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Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella.
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Academic Article
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Forward and reverse genetic analysis of microtubule motors in Chlamydomonas.
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Academic Article
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The Chlamydomonas reinhardtii ODA3 gene encodes a protein of the outer dynein arm docking complex.
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Academic Article
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The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance.
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Academic Article
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Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease.
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Academic Article
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The vertebrate primary cilium is a sensory organelle.
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Academic Article
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Oda5p, a novel axonemal protein required for assembly of the outer dynein arm and an associated adenylate kinase.
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Academic Article
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Photoreceptor intersegmental transport and retinal degeneration: a conserved pathway common to motile and sensory cilia.
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Academic Article
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Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization.
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Academic Article
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A dynein light intermediate chain, D1bLIC, is required for retrograde intraflagellar transport.
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Academic Article
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Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.
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Academic Article
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Mutants of Agrobacterium tumefaciens with elevated vir gene expression.
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Academic Article
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The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism.
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Academic Article
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An insertional mutant of Chlamydomonas reinhardtii with defective microtubule positioning.
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Academic Article
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Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes.
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Academic Article
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Differential light chain assembly influences outer arm dynein motor function.
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Academic Article
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Constitutive mutations of Agrobacterium tumefaciens transcriptional activator virG.
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Academic Article
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Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease.
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Academic Article
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Characterization of mouse IFT complex B.
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Academic Article
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The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.
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Academic Article
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Immunoprecipitation to examine protein complexes.
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Academic Article
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Cooperative binding of Agrobacterium tumefaciens VirE2 protein to single-stranded DNA.
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Academic Article
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Primary cilia regulate proliferation of amplifying progenitors in adult hippocampus: implications for learning and memory.
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Academic Article
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IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia.
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Academic Article
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DC3, the 21-kDa subunit of the outer dynein arm-docking complex (ODA-DC), is a novel EF-hand protein important for assembly of both the outer arm and the ODA-DC.
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Academic Article
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The LC7 light chains of Chlamydomonas flagellar dyneins interact with components required for both motor assembly and regulation.
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Academic Article
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Localization of transient receptor potential ion channels in primary and motile cilia of the female murine reproductive organs.
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Academic Article
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Proteomic analysis of a eukaryotic cilium.
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Academic Article
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PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts.
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Academic Article
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Radial spoke proteins of Chlamydomonas flagella.
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Academic Article
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The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly.
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Academic Article
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Nephrocystin specifically localizes to the transition zone of renal and respiratory cilia and photoreceptor connecting cilia.
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Academic Article
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Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella.
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Academic Article
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Spatial distribution of intraflagellar transport proteins in vertebrate photoreceptors.
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Academic Article
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The Chlamydomonas genome reveals the evolution of key animal and plant functions.
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Academic Article
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Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella.
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Academic Article
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virG, an Agrobacterium tumefaciens transcriptional activator, initiates translation at a UUG codon and is a sequence-specific DNA-binding protein.
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Academic Article
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Three members of the LC8/DYNLL family are required for outer arm dynein motor function.
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Academic Article
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The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex.
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Academic Article
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Targeting proteins to the ciliary membrane.
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Academic Article
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The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation.
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Academic Article
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Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse.
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Academic Article
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The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella.
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Academic Article
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Primary cilia regulate branching morphogenesis during mammary gland development.
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Academic Article
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Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome.
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Academic Article
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IFT20 is required for opsin trafficking and photoreceptor outer segment development.
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Academic Article
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Disruption of IFT complex A causes cystic kidneys without mitotic spindle misorientation.
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Academic Article
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IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.
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Academic Article
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CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors.
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Academic Article
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Analysis of ciliary membrane protein dynamics using SNAP technology.
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Academic Article
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The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly.
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Concept
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Vesicular Transport Proteins
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Concept
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Membrane Proteins
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Concept
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A Kinase Anchor Proteins
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Concept
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Protein Binding
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Concept
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Protein Subunits
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Concept
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Protein Transport
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Concept
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DNA-Binding Proteins
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Concept
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Algal Proteins
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Concept
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Serum Amyloid A Protein
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Concept
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Protein Processing, Post-Translational
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Concept
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Muscle Proteins
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Concept
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Ubiquitin-Protein Ligases
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Concept
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S-Phase Kinase-Associated Proteins
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Concept
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HSP40 Heat-Shock Proteins
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Concept
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Hedgehog Proteins
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Concept
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Intermediate Filament Proteins
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Concept
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Glial Fibrillary Acidic Protein
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Concept
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Carrier Proteins
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Concept
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Cell Cycle Proteins
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Concept
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Luminescent Proteins
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Concept
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Protein Biosynthesis
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Concept
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Protein Interaction Mapping
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Concept
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Mitogen-Activated Protein Kinase 9
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Concept
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Receptors, G-Protein-Coupled
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Concept
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Nuclear Proteins
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Concept
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Recombinant Proteins
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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Monomeric GTP-Binding Proteins
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Concept
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Dystrophin-Associated Proteins
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Concept
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rab GTP-Binding Proteins
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Proteins
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Concept
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Zebrafish Proteins
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Concept
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Microtubule-Associated Proteins
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Concept
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Protein Structure, Secondary
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Concept
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Membrane Transport Proteins
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Concept
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Cytoskeletal Proteins
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Concept
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Protein Structure, Tertiary
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Concept
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Adaptor Proteins, Signal Transducing
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Concept
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Mitogen-Activated Protein Kinase 8
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Concept
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Green Fluorescent Proteins
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Concept
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Eye Proteins
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Concept
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Bacterial Proteins
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Concept
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Recombinant Fusion Proteins
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Concept
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Calcium-Binding Proteins
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Concept
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SNARE Proteins
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Concept
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Plant Proteins
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Concept
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Vesicle-Associated Membrane Protein 3
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Concept
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Drosophila Proteins
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Concept
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JNK Mitogen-Activated Protein Kinases
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Concept
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Wnt Proteins
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Concept
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rab5 GTP-Binding Proteins
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Concept
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Molecular Motor Proteins
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Concept
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Protein Isoforms
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Concept
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Protein Conformation
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Concept
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R-SNARE Proteins
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Concept
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Proto-Oncogene Proteins
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Concept
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Light-Harvesting Protein Complexes
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Concept
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Protozoan Proteins
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Concept
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Nerve Tissue Proteins
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Concept
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Tumor Suppressor Proteins
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Academic Article
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Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.
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Academic Article
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Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system.
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Academic Article
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Distinct functions for IFT140 and IFT20 in opsin transport.
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Academic Article
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Casein kinase 1d functions at the centrosome and Golgi to promote ciliogenesis.
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Academic Article
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NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone.
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Academic Article
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IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.
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Academic Article
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ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning.
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Academic Article
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Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea.
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Academic Article
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Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis.
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Academic Article
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Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies.
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Academic Article
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The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse.
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Academic Article
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Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm.
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Academic Article
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IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo.
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Academic Article
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DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia.
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Academic Article
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Autosomal recessive IFT57 hypomorphic mutation cause ciliary transport defect in unclassified oral-facial-digital syndrome with short stature and brachymesophalangia.
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Academic Article
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Intraflagellar transport protein IFT20 is essential for male fertility and spermiogenesis in mice.
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Academic Article
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Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness.
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Academic Article
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Fifteen years of research on oral-facial-digital syndromes: from 1 to 16 causal genes.
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Academic Article
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IFT25, an intraflagellar transporter protein dispensable for ciliogenesis in somatic cells, is essential for sperm flagella formation.
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Academic Article
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BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia.
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Academic Article
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INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.
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Academic Article
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Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes.
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Academic Article
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Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert?syndrome.
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Academic Article
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Intraflagellar transporter protein (IFT27), an IFT25 binding partner, is essential for male fertility and spermiogenesis in mice.
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Academic Article
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Ift25 is not a cystic kidney disease gene but is required for early steps of kidney development.
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Academic Article
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Intraflagellar transporter protein 140 (IFT140), a component of IFT-A complex, is essential for male fertility and spermiogenesis in mice.
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Academic Article
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Intraflagellar transport is deeply integrated in hedgehog signaling.
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Academic Article
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A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia.
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Academic Article
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Intraflagellar transport protein 74 is essential for spermatogenesis and male fertility in mice?.
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Academic Article
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Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse.
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Academic Article
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Allelic Diversity in the Serum Amyloid A2 Gene and Amyloid A Amyloidosis in a Breeding Colony of Zebra Finches (Taeniopygia guttata).
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Academic Article
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Abnormal fertility, acrosome formation, IFT20 expression and localization in conditional Gmap210 knockout mice.
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Academic Article
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Ciliary Doublet Microtubules at Near-Atomic Resolution.
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Academic Article
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X Caps the Phosphate for Phospho-Rab GTPase Recognition in Ciliogenesis and Parkinson's Disease.
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Academic Article
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Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling.
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Academic Article
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Rab34 is necessary for early stages of intracellular ciliogenesis.
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Academic Article
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Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation.
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Academic Article
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E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened.
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Academic Article
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Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis.
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Academic Article
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c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease.
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Concept
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Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
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Concept
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Zinc Finger Protein Gli2
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Concept
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Lipid-Linked Proteins
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Concept
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Argonaute Proteins
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Academic Article
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Biallelic pathogenic variants in roundabout guidance receptor 1 associate with syndromic congenital anomalies of the kidney and urinary tract.
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Academic Article
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Arih2 regulates Hedgehog signaling through smoothened ubiquitylation and ER-associated degradation.
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Academic Article
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IFT74 variants cause skeletal ciliopathy and motile cilia defects in mice and humans.
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Academic Article
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Autonomous and non-cell autonomous role of cilia in structural birth defects in mice.
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Academic Article
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Contribution of intraflagellar transport to compartmentalization and maintenance of the photoreceptor cell.
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Academic Article
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Two functional forms of the Meckel-Gruber syndrome protein TMEM67 generated by proteolytic cleavage by ADAMTS9 mediate Wnt signaling and ciliogenesis.
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