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Dekker, Job
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Rotation Projects ?

Rotation Projects

Multiple rotation projects are available in several areas related to long-range gene regulation and higher order chromosome organization.  Projects include thorough analyses of the biochemical mechanisms of long-range gene regulation of specific disease-related genes, as well as large-scale analyses of chromosome organization using high-throughput genomics technologies (5C and Hi-C).  The lab employs a wide range of experimental approaches, including cell culture, protein biochemistry, microscopy, genomics as well computational approaches such as bioinformatics and modeling.  Specific rotation projects are determined dependent on the interest of the student.
One or more keywords matched the following items that are connected to Dekker, Job
Item TypeName
Academic Article A closer look at long-range chromosomal interactions.
Academic Article The three 'C' s of chromosome conformation capture: controls, controls, controls.
Academic Article Quantitative analysis of chromosome conformation capture assays (3C-qPCR).
Academic Article Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex.
Academic Article My5C: web tools for chromosome conformation capture studies.
Academic Article Capturing chromosome conformation.
Academic Article Integrating one-dimensional and three-dimensional maps of genomes.
Academic Article The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation.
Academic Article Spatial partitioning of the regulatory landscape of the X-inactivation centre.
Academic Article From cells to chromatin: capturing snapshots of genome organization with 5C technology.
Academic Article 3C-based technologies to study the shape of the genome.
Academic Article Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data.
Academic Article A mechanical basis for chromosome function.
Academic Article Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements.
Academic Article Mapping chromatin interactions by chromosome conformation capture.
Academic Article Chromosome conformation capture carbon copy technology.
Academic Article Mapping cis- and trans- chromatin interaction networks using chromosome conformation capture (3C).
Academic Article Determining spatial chromatin organization of large genomic regions using 5C technology.
Academic Article Hi-C: a method to study the three-dimensional architecture of genomes.
Academic Article The three-dimensional folding of the a-globin gene domain reveals formation of chromatin globules.
Academic Article Chromatin globules: a common motif of higher order chromosome structure?
Academic Article The structure and function of chromatin and chromosomes.
Academic Article Evidence for transcript networks composed of chimeric RNAs in human cells.
Academic Article Hi-C: a comprehensive technique to capture the conformation of genomes.
Academic Article Analysis of long-range chromatin interactions using Chromosome Conformation Capture.
Academic Article HiTC: exploration of high-throughput 'C' experiments.
Academic Article Iterative correction of Hi-C data reveals hallmarks of chromosome organization.
Academic Article Organization of the mitotic chromosome.
Concept Chromosomes, Human, Pair 16
Concept Chromosome Positioning
Concept Chromosome Structures
Concept Chromosome Inversion
Concept Chromosome Pairing
Concept X Chromosome Inactivation
Concept Chromosomes, Human, Pair 14
Concept Chromosomes, Human, Pair 1
Concept Chromosome Segregation
Concept Chromosomes, Human, Pair 21
Concept Chromosome Mapping
Concept Chromosome Aberrations
Concept X Chromosome
Academic Article Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and transcription.
Academic Article The Hitchhiker's guide to Hi-C analysis: practical guidelines.
Academic Article Two ways to fold the genome during the cell cycle: insights obtained with chromosome conformation capture.
Academic Article Chromosome Conformation Capture (3C) in Budding Yeast.
Academic Article Randomized ligation control for chromosome conformation capture.
Academic Article Chromosome Conformation Capture Carbon Copy (5C) in Budding Yeast.
Academic Article Genomics tools for unraveling chromosome architecture.
Academic Article Mapping Nucleosome Resolution Chromosome Folding in Yeast by Micro-C.
Academic Article Condensin-driven remodelling of X chromosome topology during dosage compensation.
Academic Article Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells.
Academic Article Long-Range Chromatin Interactions.
Academic Article High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila.
Academic Article The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer.
Academic Article Activation of proto-oncogenes by disruption of chromosome neighborhoods.
Academic Article The 3D Genome as Moderator of Chromosomal Communication.
Academic Article Structural organization of the inactive X chromosome in the mouse.
Academic Article Mapping the 3D genome: Aiming for consilience.
Academic Article Epigenetic characteristics of the mitotic chromosome in 1D and 3D.
Academic Article Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation.
Academic Article Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization.
Academic Article C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2.
Academic Article CBF?-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.
Academic Article Integrative detection and analysis of structural variation in cancer genomes.
Academic Article A pathway for mitotic chromosome formation.
Academic Article SMC complexes differentially compact mitotic chromosomes according to genomic context.
Academic Article The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome.
Academic Article Highly structured homolog pairing reflects functional organization of the Drosophila genome.
Academic Article The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos.
Academic Article A chromosome folding intermediate at the condensin-to-cohesin transition during telophase.
Academic Article SPEN integrates transcriptional and epigenetic control of X-inactivation.
Academic Article Ultrastructural Details of Mammalian Chromosome Architecture.
Academic Article Mechanisms and Functions of Chromosome Compartmentalization.
Academic Article Large domains of heterochromatin direct the formation of short mitotic chromosome loops.
Academic Article Detecting chromatin interactions between and along sister chromatids with SisterC.
Academic Article Chromosome-Level Assembly of the Atlantic Silverside Genome Reveals Extreme Levels of Sequence Diversity and Structural Genetic Variation.
Academic Article Hi-C 3.0: Improved Protocol for Genome-Wide Chromosome Conformation Capture.
Academic Article Erratum to: Chromosome-Level Assembly of the Atlantic Silverside Genome Reveals Extreme Levels of Sequence Diversity and Structural Genetic Variation.
Academic Article Systematic evaluation of chromosome conformation capture assays.
Academic Article Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions.
Academic Article Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization.
Academic Article Chromosome-Level Reference Genomes for Two Strains of Caenorhabditis briggsae: An Improved Platform for Comparative Genomics.
Academic Article Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization.
Academic Article Regulation of the mitotic chromosome folding machines.
Academic Article Capturing Chromosome Conformation Across Length Scales.
Academic Article Author Correction: Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization.
Academic Article Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns.
Academic Article Rules of engagement for condensins and cohesins guide mitotic chromosome formation.
Academic Article Interphase chromosome conformation is specified by distinct folding programs inherited via mitotic chromosomes or through the cytoplasm.
Academic Article The chromosome folding problem and how cells solve it.
Search Criteria
  • Chromosomes Human Pair 2