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Cantor, Sharon
One or more keywords matched the following items that are connected to
Cantor, Sharon
Item Type
Name
Academic Article
Analysis of the DNA substrate specificity of the human BACH1 helicase associated with breast cancer.
Academic Article
FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein.
Academic Article
Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand.
Concept
DNA, Single-Stranded
Academic Article
Targeting translesion synthesis (TLS) to expose replication gaps, a unique cancer vulnerability.
Academic Article
Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.
Academic Article
Revisiting the BRCA-pathway through the lens of replication gap suppression: "Gaps determine therapy response in BRCA mutant cancer".
Academic Article
Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps.
Academic Article
Unveiling the toxicity of single-stranded DNA gaps through a yeast model.
Search Criteria
DNA Single Stranded