Rotation Projects

We have identified a number of bacterial pathways that are required for bacterial viability or virulence. We are particularly interested in:

1. Phosphosignaling systems that regulate cell wall synthesis
   
2. Metabolic regulatory mechanisms that trigger the “dormancy” response observed during infection.

A variety of genetic, biochemical, and informatic methods will be used to define the functions of these genes and the role played by each during infection.