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Novel blocking human IgG directed against the pentapeptide repeat motifs of Neisseria meningitidis Lip/H.8 and Laz lipoproteins.
Immunization against a saccharide epitope accelerates clearance of experimental gonococcal infection.
Immunoglobulin Fab Fragments
Immunoglobulin Fc Fragments
A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae.
Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: Lessons from the pathogenic Neisseriae.
Gonococcal lipooligosaccharide sialylation: virulence factor and target for novel immunotherapeutics.
Human Factor H Domains 6 and 7 Fused to IgG1 Fc Are Immunotherapeutic against Neisseria gonorrhoeae.
Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody.
C4BP-IgM protein as a therapeutic approach to treat Neisseria gonorrhoeae infections.
Preclinical Efficacy of a Lipooligosaccharide Peptide Mimic Candidate Gonococcal Vaccine.
Development of Complement Factor H-Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae.
Synthetic DNA Delivery of an Optimized and Engineered Monoclonal Antibody Provides Rapid and Prolonged Protection against Experimental Gonococcal Infection.
An optimized Factor H-Fc fusion protein against multidrug-resistant Neisseria gonorrhoeae.