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Kurt-Jones, Evelyn
One or more keywords matched the following properties of Kurt-Jones, Evelyn
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  1. Expression of Toll-like receptors: Patterns of TLR expression in normal cells. Control of TLR receptor expression by environmental factors and cytokines. TLR expression in diseased tissues.


  2. Role of TLRs in disease pathogenesis: Use of knockout and genetically defined animals to study the role of TLRs in the control of bacterial or viral diseases.


  3. Structure-function studies of TLR signaling: Assessing the signaling activity of wild type and mutant TLRs (altered by site-directed mutageneis) using transient transfection and luciferase reporter gene analysis.
One or more keywords matched the following items that are connected to Kurt-Jones, Evelyn
Item TypeName
Academic Article Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells.
Academic Article HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine.
Academic Article Interleukin-1 corrects the defective autologous mixed lymphocyte response in multiple sclerosis.
Academic Article Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via toll-like receptor 2 but not toll-like receptor 4.
Academic Article Use of murine embryonic fibroblasts to define Toll-like receptor activation and specificity.
Academic Article Viruses and Toll-like receptors.
Academic Article The role of toll-like receptors in herpes simplex infection in neonates.
Academic Article MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection.
Academic Article Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages via Toll-like receptor 2.
Academic Article Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.
Academic Article Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.
Academic Article Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses.
Academic Article Cutting Edge: Antibody-mediated TLR7-dependent recognition of viral RNA.
Academic Article Toll-like receptor-mediated activation of neutrophils by influenza A virus.
Academic Article Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity.
Academic Article Methods for in vivo and in vitro analysis of innate immune responses to Helicobacter pylori infection.
Academic Article Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.
Academic Article Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling.
Academic Article Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105.
Academic Article Toll like receptors and viruses.
Academic Article Innate immunity to respiratory viruses.
Academic Article Tolls: you pay them on the way in and on the way out!
Academic Article Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle.
Academic Article MDA5 and MAVS mediate type I interferon responses to coxsackie B virus.
Academic Article Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.
Academic Article Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells.
Academic Article Alcohol-induced IL-1? in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.
Concept Cytokines
Academic Article miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).
Academic Article Expression of SARS coronavirus 1 spike protein from a herpesviral vector induces innate immune signaling and neutralizing antibody responses.
Academic Article Recurrent Respiratory Syncytial Virus Infection in a CD14-Deficient Patient.
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  • Cytokines