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Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice.
Fatty Liver, Alcoholic
Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis.
Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice.
Non-alcoholic Fatty Liver Disease
Fatty Liver Alcoholic