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One or more keywords matched the following properties of Kurt-Jones, Evelyn
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Rotation Projects

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  1. Expression of Toll-like receptors: Patterns of TLR expression in normal cells. Control of TLR receptor expression by environmental factors and cytokines. TLR expression in diseased tissues.


  2. Role of TLRs in disease pathogenesis: Use of knockout and genetically defined animals to study the role of TLRs in the control of bacterial or viral diseases.


  3. Structure-function studies of TLR signaling: Assessing the signaling activity of wild type and mutant TLRs (altered by site-directed mutageneis) using transient transfection and luciferase reporter gene analysis.
One or more keywords matched the following items that are connected to Kurt-Jones, Evelyn
Item TypeName
Academic Article Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5.
Academic Article Heterotrimeric G proteins physically associated with the lipopolysaccharide receptor CD14 modulate both in vivo and in vitro responses to lipopolysaccharide.
Academic Article Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Academic Article Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.
Academic Article MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection.
Academic Article Methods for in vivo and in vitro analysis of innate immune responses to Helicobacter pylori infection.
Academic Article Cell activation by Toll-like receptors: role of LBP and CD14.
Academic Article Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105.
Academic Article Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.
Academic Article Human and mouse colon cancer utilizes CD95 signaling for local growth and metastatic spread to liver.
Academic Article Antibodies to cell surface proteins redirect intracellular trafficking pathways.
Concept Transfection
Academic Article Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.
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  • Transfection