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Guertin, David

One or more keywords matched the following items that are connected to Guertin, David

Item Type	Name
Academic Article	Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Academic Article	Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
Academic Article	mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Academic Article	Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Academic Article	Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
Academic Article	Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
Academic Article	Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
Academic Article	Proteome and Phosphoproteome Analysis of Brown Adipocytes Reveals That RICTOR Loss Dampens Global Insulin/AKT Signaling.
Concept	Rapamycin-Insensitive Companion of mTOR Protein
Academic Article	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

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