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Guertin, David
One or more keywords matched the following items that are connected to Guertin, David
Item TypeName
Academic Article The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeast.
Academic Article Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN).
Academic Article Initiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complex.
Academic Article Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Academic Article An expanding role for mTOR in cancer.
Academic Article Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
Academic Article Interaction between the noncatalytic region of Sid1p kinase and Cdc14p is required for full catalytic activity and localization of Sid1p.
Academic Article The pharmacology of mTOR inhibition.
Academic Article Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
Academic Article Functional genomics identifies TOR-regulated genes that control growth and division.
Academic Article Defining the role of mTOR in cancer.
Academic Article mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Academic Article Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics.
Concept Protein Kinase Inhibitors
Concept Protein Kinases
Concept Protein Kinase C
Concept Protein Kinase C-alpha
Concept 3-Phosphoinositide-Dependent Protein Kinases
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  • Protein Kinases