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Guertin, David
One or more keywords matched the following properties of
Guertin, David
Property
Value
keywords
Signal Transduction
One or more keywords matched the following items that are connected to
Guertin, David
Item Type
Name
Academic Article
The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeast.
Academic Article
Cytokinesis in eukaryotes.
Academic Article
Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN).
Academic Article
Initiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complex.
Academic Article
An expanding role for mTOR in cancer.
Academic Article
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
Academic Article
The pharmacology of mTOR inhibition.
Academic Article
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.
Academic Article
Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.
Academic Article
Defining the role of mTOR in cancer.
Academic Article
mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Academic Article
Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling.
Academic Article
Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics.
Academic Article
Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells.
Academic Article
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Academic Article
mTOR-dependent cell survival mechanisms.
Academic Article
T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.
Academic Article
Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
Academic Article
Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
Academic Article
Amplification of Adipogenic Commitment by VSTM2A.
Academic Article
Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue.
Academic Article
The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond.
Academic Article
Brown fat organogenesis and maintenance requires AKT1 and AKT2.
Academic Article
Proteome and Phosphoproteome Analysis of Brown Adipocytes Reveals That RICTOR Loss Dampens Global Insulin/AKT Signaling.
Academic Article
Integrating adipocyte insulin signaling and metabolism in the multi-omics era.
Search Criteria
Signal Transduction