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Ram, Sanjay
One or more keywords matched the following items that are connected to
Ram, Sanjay
Item Type
Name
Academic Article
The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance.
Academic Article
Factor H binding and function in sialylated pathogenic neisseriae is influenced by gonococcal, but not meningococcal, porin.
Academic Article
Binding of complement factor H (fH) to Neisseria meningitidis is specific for human fH and inhibits complement activation by rat and rabbit sera.
Academic Article
Factor H and neisserial pathogenesis.
Academic Article
Impaired immunogenicity of a meningococcal factor H-binding protein vaccine engineered to eliminate factor h binding.
Academic Article
A meningococcal factor H binding protein mutant that eliminates factor H binding enhances protective antibody responses to vaccination.
Academic Article
Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycans.
Academic Article
Enhanced bacteremia in human factor H transgenic rats infected by Neisseria meningitidis.
Academic Article
Properdin is critical for antibody-dependent bactericidal activity against Neisseria gonorrhoeae that recruit C4b-binding protein.
Academic Article
The effect of human factor H on immunogenicity of meningococcal native outer membrane vesicle vaccines with over-expressed factor H binding protein.
Academic Article
Phosphoethanolamine residues on the lipid A moiety of Neisseria gonorrhoeae lipooligosaccharide modulate binding of complement inhibitors and resistance to complement killing.
Academic Article
Enhanced factor H binding to sialylated Gonococci is restricted to the sialylated lacto-N-neotetraose lipooligosaccharide species: implications for serum resistance and evidence for a bifunctional lipooligosaccharide sialyltransferase in Gonococci.
Academic Article
Human factor H interacts selectively with Neisseria gonorrhoeae and results in species-specific complement evasion.
Academic Article
Phenotypic and genotypic analyses of Neisseria gonorrhoeae isolates that express frequently recovered PorB PIA variable region types suggest that certain P1a porin sequences confer a selective advantage for urogenital tract infection.
Academic Article
Functional comparison of the binding of factor H short consensus repeat 6 (SCR 6) to factor H binding protein from Neisseria meningitidis and the binding of factor H SCR 18 to 20 to Neisseria gonorrhoeae porin.
Academic Article
Species-specificity of Neisseria gonorrhoeae infection: do human complement regulators contribute?
Academic Article
An evaluation of the role of properdin in alternative pathway activation on Neisseria meningitidis and Neisseria gonorrhoeae.
Academic Article
The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement.
Academic Article
Factor H facilitates adherence of Neisseria gonorrhoeae to complement receptor 3 on eukaryotic cells.
Academic Article
Molecular characterization of the interaction between sialylated Neisseria gonorrhoeae and factor H.
Academic Article
Does binding of complement factor H to the meningococcal vaccine antigen, factor H binding protein, decrease protective serum antibody responses?
Concept
Complement Factor I
Concept
Complement Factor H
Concept
Properdin
Academic Article
Development of a large scale human complement source for use in bacterial immunoassays.
Academic Article
Meningococcal disease and the complement system.
Academic Article
Factor H-dependent alternative pathway inhibition mediated by porin B contributes to virulence of Neisseria meningitidis.
Academic Article
Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum.
Academic Article
Fusion protein comprising factor H domains 6 and 7 and human IgG1 Fc as an antibacterial immunotherapeutic.
Academic Article
Heterogeneity in rhesus macaque complement factor H binding to meningococcal factor H binding protein (FHbp) informs selection of primates to assess immunogenicity of FHbp-based vaccines.
Academic Article
Binding of complement factor H to PorB3 and NspA enhances resistance of Neisseria meningitidis to anti-factor H binding protein bactericidal activity.
Academic Article
A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae.
Academic Article
Defining the Binding Region in Factor H to Develop a Therapeutic Factor H-Fc Fusion Protein against Non-Typeable Haemophilus influenzae.
Academic Article
Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: Lessons from the pathogenic Neisseriae.
Academic Article
Properdin Levels in Individuals with Chemotherapy-Induced Neutropenia.
Academic Article
Gonococcal lipooligosaccharide sialylation: virulence factor and target for novel immunotherapeutics.
Academic Article
Human Factor H Domains 6 and 7 Fused to IgG1 Fc Are Immunotherapeutic against Neisseria gonorrhoeae.
Academic Article
Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission.
Academic Article
Factor H-IgG Chimeric Proteins as a Therapeutic Approach against the Gram-Positive Bacterial Pathogen Streptococcus pyogenes.
Academic Article
Role of Gonococcal Neisserial Surface Protein A (NspA) in Serum Resistance and Comparison of Its Factor H Binding Properties with Those of Its Meningococcal Counterpart.
Academic Article
The Molecular Basis of Human IgG-Mediated Enhancement of C4b-Binding Protein Recruitment to Group A Streptococcus.
Academic Article
Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody.
Academic Article
Blood treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts.
Academic Article
Therapeutic CMP-Nonulosonates against Multidrug-Resistant Neisseria gonorrhoeae.
Academic Article
Antibacterial Fusion Proteins Enhance Moraxella catarrhalis Killing.
Academic Article
Development of Complement Factor H-Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae.
Academic Article
Host tropism determination by convergent evolution of immunological evasion in the Lyme disease system.
Academic Article
Alternative pathway amplification and infections.
Academic Article
An optimized Factor H-Fc fusion protein against multidrug-resistant Neisseria gonorrhoeae.
Academic Article
Gardnerella Vaginolysin Potentiates Glycan Molecular Mimicry by Neisseria gonorrhoeae.
Academic Article
Mechanisms by which Factor H protects Trypanosoma cruzi from the alternative pathway of complement.
Academic Article
PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration.
Search Criteria
Properdin