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Watts, Jonathan
One or more keywords matched the following items that are connected to Watts, Jonathan
Item TypeName
Concept Nucleic Acids
Concept Peptide Nucleic Acids
Academic Article Next-Generation Peptide Nucleic Acid Chimeras Exhibit High Affinity and Potent Gene Silencing.
Academic Article Nucleic Acid Therapeutics for Neurological Diseases.
Academic Article Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility.
Academic Article Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs.
Academic Article 2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity.
Academic Article Effect of chemical modifications on modulation of gene expression by duplex antigene RNAs that are complementary to non-coding transcripts at gene promoters.
Academic Article Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing.
Academic Article Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA.
Academic Article Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts.
Academic Article G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects.
Academic Article Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo.
Academic Article Dendritic amphiphilic siRNA: Selective albumin binding, in?vivo efficacy, and low toxicity.
Academic Article A combinatorial approach for achieving CNS-selective RNAi.
Academic Article Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo.
Academic Article Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+ and Mg2+ in the formulation.
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  • Nucleic Acids