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Shim, Jae-Hyuck

One or more keywords matched the following items that are connected to Shim, Jae-Hyuck

Item Type	Name
Concept	Signal Transduction
Academic Article	p38a MAPK is required for tooth morphogenesis and enamel secretion.
Academic Article	Cereblon negatively regulates TLR4 signaling through the attenuation of ubiquitination of TRAF6.
Academic Article	Phosphoinositide-dependent kinase-1 inhibits TRAF6 ubiquitination by interrupting the formation of TAK1-TAB2 complex in TLR4 signaling.
Academic Article	CHMP5 controls bone turnover rates by dampening NF-?B activity in osteoclasts.
Academic Article	TAK1-ECSIT-TRAF6 complex plays a key role in the TLR4 signal to activate NF-?B.
Academic Article	Ubiquitination of ECSIT is crucial for the activation of p65/p50 NF-?Bs in Toll-like receptor 4 signaling.
Academic Article	S6K1 negatively regulates TAK1 activity in the toll-like receptor signaling pathway.
Academic Article	Zinc inhibits osteoclast differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway.
Academic Article	Salt-inducible kinases 1 and 3 negatively regulate Toll-like receptor 4-mediated signal.
Academic Article	Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice.
Academic Article	Qualitative and quantitative differences in the intensity of Fas-mediated intracellular signals determine life and death in T cells.
Academic Article	TAK1 mediates BMP signaling in cartilage.
Academic Article	TAK1 is an essential regulator of BMP signalling in cartilage.
Academic Article	Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex.
Academic Article	CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis.
Academic Article	TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo.
Academic Article	PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation.
Academic Article	Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.
Academic Article	Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction.
Academic Article	Post-translational control of T cell development by the ESCRT protein CHMP5.
Academic Article	Endothelial-specific inhibition of NF-?B enhances functional haematopoiesis.
Academic Article	Osteoblast-Osteoclast Communication and Bone Homeostasis.
Academic Article	SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts.
Academic Article	Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration.

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Signal Transduction