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Krieg, Arthur

One or more keywords matched the following items that are connected to Krieg, Arthur

Item Type	Name
Concept	CpG Islands
Academic Article	A role for Toll in autoimmunity.
Academic Article	Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells.
Academic Article	Immunostimulatory oligodeoxynucleotides containing CpG motifs enhance the efficacy of monoclonal antibody therapy of lymphoma.
Academic Article	Biodistribution and metabolism of immunostimulatory oligodeoxynucleotide CPG 7909 in mouse and rat tissues following subcutaneous administration.
Academic Article	Antitumor mechanisms of oligodeoxynucleotides with CpG and polyG motifs in murine prostate cancer cells: decrease of NF-kappaB and AP-1 binding activities and induction of apoptosis.
Academic Article	Highly immunostimulatory CpG-free oligodeoxynucleotides for activation of human leukocytes.
Academic Article	CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity.
Academic Article	Unmethylated CpG-containing oligodeoxynucleotides inhibit apoptosis in WEHI 231 B lymphocytes induced by several agents: evidence for blockade of apoptosis at a distal signalling step.
Academic Article	Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization.
Academic Article	CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen.
Academic Article	CpG oligodeoxyribonucleotides rescue mature spleen B cells from spontaneous apoptosis and promote cell cycle entry.
Academic Article	CpG oligonucleotides enhance the tumor antigen-specific immune response of a granulocyte macrophage colony-stimulating factor-based vaccine strategy in neuroblastoma.
Academic Article	Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA.
Academic Article	CpG DNA rescue of murine B lymphoma cells from anti-IgM-induced growth arrest and programmed cell death is associated with increased expression of c-myc and bcl-xL.
Academic Article	CpG oligodeoxynucleotides stimulate IFN-gamma-inducible protein-10 production in human B cells.
Academic Article	B cells express Ly-6C in a Th1 but not Th2 cytokine environment.
Academic Article	The role of CpG dinucleotides in DNA vaccines.
Academic Article	CpG DNA rescue from anti-IgM-induced WEHI-231 B lymphoma apoptosis via modulation of I kappa B alpha and I kappa B beta and sustained activation of nuclear factor-kappa B/c-Rel.
Academic Article	Accumulation of glutathione disulfide mediates NF-kappaB activation during immune stimulation with CpG DNA.
Academic Article	Synergy between CpG- or non-CpG DNA and specific antigen for B cell activation.
Academic Article	CpG ODN enhances uptake of bacteria by mouse macrophages.
Academic Article	CpG-A-induced monocyte IFN-gamma-inducible protein-10 production is regulated by plasmacytoid dendritic cell-derived IFN-alpha.
Academic Article	CpG DNA: a novel immunomodulator.
Academic Article	CpG oligodeoxynucleotide enhances immunity against blood-stage malaria infection in mice parenterally immunized with a yeast-expressed 19 kDa carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (MSP1(19)) formulated in oil-based Montanides.
Academic Article	CpG motifs: the active ingredient in bacterial extracts?
Academic Article	CpG motifs in bacterial DNA and their immune effects.
Academic Article	Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy.
Academic Article	Combining vaccination and postexposure CpG therapy provides optimal protection against lethal sepsis in a biodefense model of human melioidosis.
Academic Article	CpG oligodeoxynucleotides down-regulate macrophage class II MHC antigen processing.
Academic Article	CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma.
Academic Article	CpG DNA and LPS induce distinct patterns of activation in human monocytes.
Academic Article	CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma.
Academic Article	Mechanism of action of CpG DNA.
Academic Article	Mechanisms and applications of immune stimulatory CpG oligodeoxynucleotides.
Academic Article	Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor.
Academic Article	Convergence of CpG DNA- and BCR-mediated signals at the c-Jun N-terminal kinase and NF-kappaB activation pathways: regulation by mitogen-activated protein kinases.
Academic Article	Immunostimulatory CpG oligonucleotides enhance the immune response of anti-idiotype vaccine that mimics carcinoembryonic antigen.
Academic Article	CpG oligodeoxynucleotides can circumvent the Th2 polarization of neonatal responses to vaccines but may fail to fully redirect Th2 responses established by neonatal priming.
Academic Article	Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity.
Academic Article	Bacterial DNA and CpG-containing oligodeoxynucleotides activate cutaneous dendritic cells and induce IL-12 production: implications for the augmentation of Th1 responses.
Academic Article	Bacterial DNA or oligonucleotides containing unmethylated CpG motifs can minimize lipopolysaccharide-induced inflammation in the lower respiratory tract through an IL-12-dependent pathway.
Academic Article	Phagocytic antigen processing and effects of microbial products on antigen processing and T-cell responses.
Academic Article	Synthetic oligodeoxynucleotides containing CpG motifs enhance immunogenicity of a peptide malaria vaccine in Aotus monkeys.
Academic Article	A novel class of immune-stimulatory CpG oligodeoxynucleotides unifies high potency in type I interferon induction with preferred structural properties.
Academic Article	Mechanisms and therapeutic applications of immune stimulatory cpG DNA.
Academic Article	Mechanism and function of a newly identified CpG DNA motif in human primary B cells.
Academic Article	Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo.
Academic Article	Rescue of B cells from apoptosis by immune stimulatory CpG DNA.
Academic Article	Immune effects and therapeutic applications of CpG motifs in bacterial DNA.
Academic Article	Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides.
Academic Article	Causing a commotion in the blood: immunotherapy progresses from bacteria to bacterial DNA.
Academic Article	Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo.
Academic Article	Immune effects and mechanisms of action of CpG motifs.
Academic Article	CpG DNA is an effective oral adjuvant to protein antigens in mice.
Academic Article	CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms.
Academic Article	Therapeutic potential of Toll-like receptor 9 activation.
Academic Article	Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens.
Academic Article	Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells.
Academic Article	Now I know my CpGs.
Academic Article	Induction of autoantibody production but not autoimmune disease in HEL transgenic mice vaccinated with HEL in combination with CpG or control oligodeoxynucleotides.
Academic Article	Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.
Academic Article	NK cells activated in vivo by bacterial DNA control the intracellular growth of Francisella tularensis LVS.
Academic Article	CpG DNA induces cyclooxygenase-2 expression and prostaglandin production.
Academic Article	CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans.
Academic Article	Direct immunologic activities of CpG DNA and implications for gene therapy.
Academic Article	Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila.
Academic Article	Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs.
Academic Article	Signal transduction induced by immunostimulatory CpG DNA.
Academic Article	Minding the Cs and Gs.
Academic Article	CpG oligonucleotides as immune adjuvants.
Academic Article	Whole blood cultures to assess the immunostimulatory activities of CpG oligodeoxynucleotides.
Academic Article	Modulation of CpG oligodeoxynucleotide-mediated immune stimulation by locked nucleic acid (LNA).
Academic Article	Enhancing vaccines with immune stimulatory CpG DNA.
Academic Article	New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site.
Academic Article	Decreased cytotoxic T cell activity generated by co-administration of PSA vaccine and CpG ODN is associated with increased tumor protection in a mouse model of prostate cancer.
Academic Article	Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs.
Academic Article	From bugs to drugs: therapeutic immunomodulation with oligodeoxynucleotides containing CpG sequences from bacterial DNA.
Academic Article	Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists.
Academic Article	Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma.
Academic Article	Immunostimulatory CpG oligodeoxynucleotide confers protection in a murine model of infection with Burkholderia pseudomallei.
Academic Article	Type I interferon is the primary regulator of inducible Ly-6C expression on T cells.
Academic Article	CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kappaB activation.
Academic Article	Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
Academic Article	CpG motif identification for veterinary and laboratory species demonstrates that sequence recognition is highly conserved.
Academic Article	Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists.
Academic Article	CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge.
Academic Article	An innate immune defense mechanism based on the recognition of CpG motifs in microbial DNA.
Academic Article	Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs.
Academic Article	Lactoferrin binds CpG-containing oligonucleotides and inhibits their immunostimulatory effects on human B cells.
Academic Article	IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides.
Academic Article	Enhancement of infectious disease vaccines through TLR9-dependent recognition of CpG DNA.
Academic Article	Lipopolysaccharide and CpG DNA synergize for tumor necrosis factor-alpha production through activation of NF-kappaB.
Academic Article	Comparison of CpG s-ODNs, chromatin immune complexes, and dsDNA fragment immune complexes in the TLR9-dependent activation of rheumatoid factor B cells.

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CpG Islands