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Concept
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Cytokines
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Academic Article
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CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection.
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Academic Article
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Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses.
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Academic Article
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Induction of systemic TH1-like innate immunity in normal volunteers following subcutaneous but not intravenous administration of CPG 7909, a synthetic B-class CpG oligodeoxynucleotide TLR9 agonist.
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Academic Article
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Role of mitogen-activated protein kinases in CpG DNA-mediated IL-10 and IL-12 production: central role of extracellular signal-regulated kinase in the negative feedback loop of the CpG DNA-mediated Th1 response.
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Academic Article
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CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity.
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Academic Article
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Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoid dendritic cells.
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Academic Article
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Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma.
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Academic Article
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Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA.
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Academic Article
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CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species.
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Academic Article
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Safety, pharmacokinetics and immune effects in normal volunteers of CPG 10101 (ACTILON), an investigational synthetic toll-like receptor 9 agonist.
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Academic Article
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TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells.
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Academic Article
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Stimulation via Toll-like receptor 9 reduces Cryptococcus neoformans-induced pulmonary inflammation in an IL-12-dependent manner.
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Academic Article
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CpG-DNA protects against a lethal orthopoxvirus infection in a murine model.
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Academic Article
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CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract.
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Academic Article
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CpG DNA and LPS induce distinct patterns of activation in human monocytes.
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Academic Article
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CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma.
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Academic Article
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Immunostimulatory potential of silencing RNAs can be mediated by a non-uridine-rich toll-like receptor 7 motif.
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Academic Article
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The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques.
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Academic Article
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Immunology. The toll of cathepsin K deficiency.
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Academic Article
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Induction and regulation of Th1-inducing cytokines by bacterial DNA, lipopolysaccharide, and heat-inactivated bacteria.
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Academic Article
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APC stimulated by CpG oligodeoxynucleotide enhance activation of MHC class I-restricted T cells.
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Academic Article
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Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells.
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Academic Article
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Immunopharmacology of CpG oligodeoxynucleotides and ribavirin.
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Academic Article
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Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila.
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Academic Article
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Minding the Cs and Gs.
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Academic Article
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CpG oligonucleotides as immune adjuvants.
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Academic Article
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A combination of Flt3 ligand cDNA and CpG ODN as nasal adjuvant elicits NALT dendritic cells for prolonged mucosal immunity.
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Academic Article
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Modulation of CpG oligodeoxynucleotide-mediated immune stimulation by locked nucleic acid (LNA).
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Academic Article
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Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs.
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Academic Article
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Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma.
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Academic Article
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Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
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Academic Article
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Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs.
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Academic Article
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NIH conference. Systemic lupus erythematosus.
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Academic Article
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Distinct CpG oligonucleotide sequences activate human gamma delta T cells via interferon-alpha/-beta.
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Academic Article
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Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation.
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Academic Article
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High mobility group B1 protein suppresses the human plasmacytoid dendritic cell response to TLR9 agonists.
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