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Krieg, Arthur

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Item Type	Name
Concept	Drug Administration Schedule
Concept	Protein Subunits
Concept	Staphylococcus aureus
Concept	Sequence Analysis, DNA
Concept	2',5'-Oligoadenylate Synthetase
Concept	Genes, env
Concept	RNA, Small Nuclear
Concept	Subcellular Fractions
Concept	Survival Rate
Concept	Genes, Regulator
Concept	RNA, Small Interfering
Concept	MAP Kinase Signaling System
Concept	Sequence Analysis, RNA
Concept	T-Cell Antigen Receptor Specificity
Concept	Prostaglandin-Endoperoxide Synthases
Concept	Tumor Suppressor Protein p53
Concept	Magnetic Resonance Spectroscopy
Concept	Stereoisomerism
Concept	Safety
Concept	Genes, MHC Class II
Concept	B-Lymphocyte Subsets
Concept	Spleen Focus-Forming Viruses
Concept	Cell Survival
Concept	Receptors, Cell Surface
Concept	Proto-Oncogenes
Concept	Genes, Viral
Concept	Freund's Adjuvant
Concept	Amino Acid Sequence
Concept	Stress, Physiological
Concept	Sheep Diseases
Concept	Saccharomyces cerevisiae
Concept	Cohort Studies
Concept	Specific Pathogen-Free Organisms
Concept	Streptococcus pneumoniae
Concept	Injections, Subcutaneous
Concept	Reference Standards
Concept	T-Lymphocyte Subsets
Concept	Prostate-Specific Antigen
Concept	Herpes Simplex
Concept	Intracellular Signaling Peptides and Proteins
Concept	Protein Synthesis Inhibitors
Concept	Genes, bcl-2
Concept	Cell-Free System
Concept	Saponins
Concept	Simian Acquired Immunodeficiency Syndrome
Concept	Molecular Structure
Concept	Conserved Sequence
Concept	Immune Sera
Concept	Adjuvants, Immunologic
Concept	Retrospective Studies
Concept	Repetitive Sequences, Nucleic Acid
Concept	Organ Size
Concept	Stem Cells
Concept	Species Specificity
Concept	Cell Separation
Concept	Granulocyte-Macrophage Colony-Stimulating Factor
Concept	Genes, p53
Concept	Drug Synergism
Concept	Signal Transduction
Concept	Nucleic Acid Conformation
Concept	Nucleic Acid Synthesis Inhibitors
Concept	Simian Immunodeficiency Virus
Concept	Merozoite Surface Protein 1
Concept	Hematopoietic Stem Cells
Concept	Drug Screening Assays, Antitumor
Concept	Hepatitis B Surface Antigens
Concept	Reactive Oxygen Species
Concept	Adaptor Proteins, Signal Transducing
Concept	Solubility
Concept	Genes, Reporter
Concept	Carcinoma, Non-Small-Cell Lung
Concept	Antigens, Surface
Concept	Survival Analysis
Concept	Sex Factors
Concept	Vaccines, Synthetic
Concept	Self Administration
Concept	Sheep
Concept	Sjogren's Syndrome
Concept	Murine Acquired Immunodeficiency Syndrome
Concept	Electrophoretic Mobility Shift Assay
Concept	Binding Sites
Concept	Saccharomyces cerevisiae Proteins
Concept	Mice, SCID
Concept	Mice, Inbred Strains
Concept	Genes, myc
Concept	Sphingomyelins
Concept	Neoplasm Staging
Concept	Antibody Specificity
Concept	Sputum
Concept	Macromolecular Substances
Concept	Prospective Studies
Concept	Secretory Rate
Concept	Immune System
Concept	Least-Squares Analysis
Concept	Radiation-Sensitizing Agents
Concept	Sarcoma, Experimental
Concept	Immunoglobulin Class Switching
Concept	Staining and Labeling
Concept	Spleen
Concept	Systemic Inflammatory Response Syndrome
Concept	RNA Splicing
Concept	Virus Shedding
Concept	Rats, Sprague-Dawley
Concept	Swine
Concept	United States
Concept	Lupus Erythematosus, Systemic
Concept	United States Food and Drug Administration
Concept	Skin Neoplasms
Concept	Structure-Activity Relationship
Concept	Immunization, Secondary
Concept	Carrier State
Concept	Skin
Concept	Single-Strand Specific DNA and RNA Endonucleases
Concept	Streptococcus agalactiae
Concept	Gene Silencing
Concept	Base Sequence
Concept	Follow-Up Studies
Concept	DNA, Single-Stranded
Concept	Vaccines, Subunit
Concept	Mice, Mutant Strains
Concept	Molecular Sequence Data
Concept	Lymphocyte Subsets
Concept	SAIDS Vaccines
Concept	Heparitin Sulfate
Academic Article	Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs.
Academic Article	CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection.
Academic Article	C-Class CpG ODN: sequence requirements and characterization of immunostimulatory activities on mRNA level.
Academic Article	Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses.
Academic Article	From A to Z on CpG.
Academic Article	CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B HBV vaccine in healthy adults: a double-blind phase I/II study.
Academic Article	Expression of an endogenous retroviral transcript is associated with murine lupus.
Academic Article	Negative control region at the 5' end of murine leukemia virus long terminal repeats.
Academic Article	Induction of systemic TH1-like innate immunity in normal volunteers following subcutaneous but not intravenous administration of CPG 7909, a synthetic B-class CpG oligodeoxynucleotide TLR9 agonist.
Academic Article	Role of mitogen-activated protein kinases in CpG DNA-mediated IL-10 and IL-12 production: central role of extracellular signal-regulated kinase in the negative feedback loop of the CpG DNA-mediated Th1 response.
Academic Article	A role for Toll in autoimmunity.
Academic Article	Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells.
Academic Article	Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma.
Academic Article	Immunostimulatory oligodeoxynucleotides containing CpG motifs enhance the efficacy of monoclonal antibody therapy of lymphoma.
Academic Article	Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.
Academic Article	Bacterial DNA-induced NK cell IFN-gamma production is dependent on macrophage secretion of IL-12.
Academic Article	Biodistribution and metabolism of immunostimulatory oligodeoxynucleotide CPG 7909 in mouse and rat tissues following subcutaneous administration.
Academic Article	Antitumor mechanisms of oligodeoxynucleotides with CpG and polyG motifs in murine prostate cancer cells: decrease of NF-kappaB and AP-1 binding activities and induction of apoptosis.
Academic Article	Highly immunostimulatory CpG-free oligodeoxynucleotides for activation of human leukocytes.
Academic Article	CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity.
Academic Article	Unmethylated CpG-containing oligodeoxynucleotides inhibit apoptosis in WEHI 231 B lymphocytes induced by several agents: evidence for blockade of apoptosis at a distal signalling step.
Academic Article	Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization.
Academic Article	Exon skipping therapy for Duchenne muscular dystrophy.
Academic Article	Interleukin-10 functions in vitro and in vivo to inhibit bacterial DNA-induced secretion of interleukin-12.
Academic Article	Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoid dendritic cells.
Academic Article	CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen.
Academic Article	CpG oligodeoxyribonucleotides rescue mature spleen B cells from spontaneous apoptosis and promote cell cycle entry.
Academic Article	CpG oligonucleotides enhance the tumor antigen-specific immune response of a granulocyte macrophage colony-stimulating factor-based vaccine strategy in neuroblastoma.
Academic Article	Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA.
Academic Article	CpG DNA rescue of murine B lymphoma cells from anti-IgM-induced growth arrest and programmed cell death is associated with increased expression of c-myc and bcl-xL.
Academic Article	Rapid immune activation by CpG motifs in bacterial DNA. Systemic induction of IL-6 transcription through an antioxidant-sensitive pathway.
Academic Article	Toll-free vaccines?
Academic Article	CpG oligodeoxynucleotides augment the murine immune response to the Yersinia pestis F1-V vaccine in bubonic and pneumonic models of plague.
Academic Article	Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848.
Academic Article	CpG oligodeoxynucleotides stimulate IFN-gamma-inducible protein-10 production in human B cells.
Academic Article	Induction of CD8 T-cell-specific systemic and mucosal immunity against herpes simplex virus with CpG-peptide complexes.
Academic Article	The ability of CpG oligonucleotides to protect mice against Francisella tularensis live vaccine strain but not fully virulent F. tularensis subspecies holarctica is reflected in cell-based assays.
Academic Article	Multifunctional poly(methacrylate) polyplex libraries: A platform for gene delivery inspired by nature.
Academic Article	B cells express Ly-6C in a Th1 but not Th2 cytokine environment.
Academic Article	Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine.
Academic Article	Comparative analysis of murine marrow-derived dendritic cells generated by Flt3L or GM-CSF/IL-4 and matured with immune stimulatory agents on the in vivo induction of antileukemia responses.
Academic Article	Antiinfective applications of toll-like receptor 9 agonists.
Academic Article	The role of CpG dinucleotides in DNA vaccines.
Academic Article	Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself.
Academic Article	CpG DNA rescue from anti-IgM-induced WEHI-231 B lymphoma apoptosis via modulation of I kappa B alpha and I kappa B beta and sustained activation of nuclear factor-kappa B/c-Rel.
Academic Article	Accumulation of glutathione disulfide mediates NF-kappaB activation during immune stimulation with CpG DNA.
Academic Article	CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species.
Academic Article	Safety, pharmacokinetics and immune effects in normal volunteers of CPG 10101 (ACTILON), an investigational synthetic toll-like receptor 9 agonist.
Academic Article	[Stem cell-induced liver regeneration].
Academic Article	TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells.
Academic Article	CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus.
Academic Article	Synergy between CpG- or non-CpG DNA and specific antigen for B cell activation.
Academic Article	Cyclosporin A enhances IL-12 production by CpG motifs in bacterial DNA and synthetic oligodeoxynucleotides.
Academic Article	CpG ODN enhances uptake of bacteria by mouse macrophages.
Academic Article	CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice.
Academic Article	CpG-A-induced monocyte IFN-gamma-inducible protein-10 production is regulated by plasmacytoid dendritic cell-derived IFN-alpha.
Academic Article	Phase I trial of toll-like receptor 9 agonist PF-3512676 with and following rituximab in patients with recurrent indolent and aggressive non Hodgkin's lymphoma.
Academic Article	CpG oligonucleotides protect against Venezuelan equine encephalitis virus infection in a route-dependent manner.
Academic Article	CpG DNA: a novel immunomodulator.
Academic Article	Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage.
Academic Article	The toll of too much TLR7.
Academic Article	CpG oligodeoxynucleotide enhances immunity against blood-stage malaria infection in mice parenterally immunized with a yeast-expressed 19 kDa carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (MSP1(19)) formulated in oil-based Montanides.
Academic Article	CpG still rocks! Update on an accidental drug.
Academic Article	CpG motifs: the active ingredient in bacterial extracts?
Academic Article	Activation of innate immunity in healthy Macaca mulatta macaques by a single subcutaneous dose of GMP CpG 7909: safety data and interferon-inducible protein-10 kinetics for humans and macaques.
Academic Article	CpG motifs in bacterial DNA and their immune effects.
Academic Article	Stimulation via Toll-like receptor 9 reduces Cryptococcus neoformans-induced pulmonary inflammation in an IL-12-dependent manner.
Academic Article	A role for endogenous retroviral sequences in the regulation of lymphocyte activation.
Academic Article	On the quality control of antisense oligonucleotides.
Academic Article	Increased expression of novel full-length endogenous mink cell focus-forming-related transcripts in autoimmune mouse strains.
Academic Article	Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy.
Academic Article	Identification of an oligodeoxynucleotide sequence motif that specifically inhibits phosphorylation by protein tyrosine kinases.
Academic Article	CpG-DNA protects against a lethal orthopoxvirus infection in a murine model.
Academic Article	CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract.
Academic Article	AIMing 2 detect foreign DNA.
Academic Article	Combining vaccination and postexposure CpG therapy provides optimal protection against lethal sepsis in a biodefense model of human melioidosis.
Academic Article	PD-1 and Tim-3 regulate the expansion of tumor antigen-specific CD8? T cells induced by melanoma vaccines.
Academic Article	Clinical evaluation of safety and immunogenicity of PADRE-cytomegalovirus (CMV) and tetanus-CMV fusion peptide vaccines with or without PF03512676 adjuvant.
Academic Article	CpG oligodeoxynucleotides down-regulate macrophage class II MHC antigen processing.
Academic Article	Oral pretreatment of mice with CpG DNA reduces susceptibility to oral or intraperitoneal challenge with virulent Listeria monocytogenes.
Academic Article	CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma.
Academic Article	AIMing 2 defend against intracellular pathogens.
Academic Article	Inhibitory oligonucleotides block the induction of AP-1 transcription factor by stimulatory CpG oligonucleotides in B cells.
Academic Article	CpG DNA rescues B cells from apoptosis by activating NFkappaB and preventing mitochondrial membrane potential disruption via a chloroquine-sensitive pathway.
Academic Article	Interruption of a transforming growth factor alpha autocrine loop in Caco-2 cells by antisense oligodeoxynucleotides.
Academic Article	The role of CpG motifs in innate immunity.
Academic Article	Attenuated cytokine responses in porcine lymph node cells stimulated with CpG DNA are associated with low frequency of IFNalpha-producing cells and TLR9 mRNA expression.
Academic Article	CpG DNA: trigger of sepsis, mediator of protection, or both?
Academic Article	Mechanisms and applications of immune stimulatory CpG oligodeoxynucleotides.
Academic Article	Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor.
Academic Article	CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic mice.
Academic Article	Convergence of CpG DNA- and BCR-mediated signals at the c-Jun N-terminal kinase and NF-kappaB activation pathways: regulation by mitogen-activated protein kinases.
Academic Article	Immunostimulatory CpG oligonucleotides enhance the immune response of anti-idiotype vaccine that mimics carcinoembryonic antigen.
Academic Article	CpG oligodeoxynucleotides can circumvent the Th2 polarization of neonatal responses to vaccines but may fail to fully redirect Th2 responses established by neonatal priming.
Academic Article	CPG 7909 adjuvant improves hepatitis B virus vaccine seroprotection in antiretroviral-treated HIV-infected adults.
Academic Article	Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers.
Academic Article	Interdisciplinary treatment of primary hepatic angiosarcoma: emergency tumor embolization followed by elective surgery.
Academic Article	Bacterial DNA and CpG-containing oligodeoxynucleotides activate cutaneous dendritic cells and induce IL-12 production: implications for the augmentation of Th1 responses.
Academic Article	Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms.
Academic Article	Encapsulation status of papillary thyroid microcarcinomas is associated with the risk of lymph node metastases and tumor multifocality.
Academic Article	Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA.
Academic Article	Multiple endogenous xenotropic and mink cell focus-forming murine leukemia virus-related transcripts are induced by polyclonal immune activators.
Academic Article	Immunostimulatory potential of silencing RNAs can be mediated by a non-uridine-rich toll-like receptor 7 motif.
Academic Article	Bacterial DNA or oligonucleotides containing unmethylated CpG motifs can minimize lipopolysaccharide-induced inflammation in the lower respiratory tract through an IL-12-dependent pathway.
Academic Article	CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells.
Academic Article	The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques.
Academic Article	Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery.
Academic Article	Synthetic oligodeoxynucleotides containing CpG motifs enhance immunogenicity of a peptide malaria vaccine in Aotus monkeys.
Academic Article	Antibody repertoire development in fetal and neonatal piglets. IX. Three pathogen-associated molecular patterns act synergistically to allow germfree piglets to respond to type 2 thymus-independent and thymus-dependent antigens.
Academic Article	Immunology. The toll of cathepsin K deficiency.
Academic Article	A novel class of immune-stimulatory CpG oligodeoxynucleotides unifies high potency in type I interferon induction with preferred structural properties.
Academic Article	Cancer and inflammation: promise for biologic therapy.
Academic Article	Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8.
Academic Article	Induction and regulation of Th1-inducing cytokines by bacterial DNA, lipopolysaccharide, and heat-inactivated bacteria.
Academic Article	Mechanisms and therapeutic applications of immune stimulatory cpG DNA.
Academic Article	Can immunization precipitate connective tissue disease? Report of five cases of systemic lupus erythematosus and review of the literature.
Academic Article	Mechanism and function of a newly identified CpG DNA motif in human primary B cells.
Academic Article	Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo.
Academic Article	Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses.
Academic Article	Administration of a phosphorothioate oligonucleotide antisense to murine endogenous retroviral MCF env causes immune effects in vivo in a sequence-specific manner.
Academic Article	A CpG oligonucleotide can protect mice from a low aerosol challenge dose of Burkholderia mallei.
Academic Article	Inhibition of T4 polynucleotide kinase activity by phosphorothioate and chimeric oligodeoxynucleotides.
Academic Article	Rescue of B cells from apoptosis by immune stimulatory CpG DNA.
Academic Article	Role of endogenous retroviruses in autoimmune diseases.
Academic Article	CpG oligodeoxynucleotide and Montanide ISA 51 adjuvant combination enhanced the protective efficacy of a subunit malaria vaccine.
Academic Article	Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides.
Academic Article	Causing a commotion in the blood: immunotherapy progresses from bacteria to bacterial DNA.
Academic Article	APC stimulated by CpG oligodeoxynucleotide enhance activation of MHC class I-restricted T cells.
Academic Article	Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo.
Academic Article	Immune effects and mechanisms of action of CpG motifs.
Academic Article	Effect of cyclophosphamide, total body irradiation, and zidovudine on retrovirus proliferation and disease progression in murine AIDS.
Academic Article	CpG DNA is an effective oral adjuvant to protein antigens in mice.
Academic Article	TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.
Academic Article	CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms.
Academic Article	P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides.
Academic Article	Therapeutic potential of Toll-like receptor 9 activation.
Academic Article	Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens.
Academic Article	Endogenous secretion of IL-4 maintains growth and Thy-1 expression of a transformed B cell clone.
Academic Article	Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells.
Academic Article	Randomized phase II trial of a toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer.
Academic Article	Heterogeneous expression and coordinate regulation of endogenous retroviral sequences in human peripheral blood mononuclear cells.
Academic Article	Immunopharmacology of CpG oligodeoxynucleotides and ribavirin.
Academic Article	Endogenous retroviruses: potential etiologic agents in autoimmunity.
Academic Article	Chronic ethanol ingestion by mice increases expression of CD80 and CD86 by activated macrophages.
Academic Article	Paclitaxel reduces regulatory T cell numbers and inhibitory function and enhances the anti-tumor effects of the TLR9 agonist PF-3512676 in the mouse.
Academic Article	Now I know my CpGs.
Academic Article	Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.
Academic Article	NK cells activated in vivo by bacterial DNA control the intracellular growth of Francisella tularensis LVS.
Academic Article	CpG DNA induces cyclooxygenase-2 expression and prostaglandin production.
Academic Article	Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy.
Academic Article	Synthetic unmethylated cytosine-phosphate-guanosine oligodeoxynucleotides are potent stimulators of antileukemia responses in naive and bone marrow transplant recipients.
Academic Article	CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans.
Academic Article	Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment.
Academic Article	Direct immunologic activities of CpG DNA and implications for gene therapy.
Academic Article	Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila.
Academic Article	Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs.
Academic Article	CpG motifs in bacterial DNA trigger direct B-cell activation.
Academic Article	Signal transduction induced by immunostimulatory CpG DNA.
Academic Article	CpG oligonucleotides as immune adjuvants.
Academic Article	Stimulation of innate immune responses by CpG oligodeoxynucleotide in newborn lambs can reduce bovine herpesvirus-1 shedding.
Academic Article	Oligonucleotides with novel, cationic backbone substituents: aminoethylphosphonates.
Academic Article	Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers.
Academic Article	Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities.
Academic Article	Stage-specific oligonucleotide uptake in murine bone marrow B-cell precursors.
Academic Article	A possible cause of joint destruction in septic arthritis.
Academic Article	Nonspecific suppression of [3H]thymidine incorporation by "control" oligonucleotides.
Academic Article	A combination of Flt3 ligand cDNA and CpG ODN as nasal adjuvant elicits NALT dendritic cells for prolonged mucosal immunity.
Academic Article	Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan.
Academic Article	Whole blood cultures to assess the immunostimulatory activities of CpG oligodeoxynucleotides.
Academic Article	Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides.
Academic Article	Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice.
Academic Article	Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway.
Academic Article	Modulation of CpG oligodeoxynucleotide-mediated immune stimulation by locked nucleic acid (LNA).
Academic Article	Enhancing vaccines with immune stimulatory CpG DNA.
Academic Article	Timing of immunosuppression in the natural history of autoimmune diseases.
Academic Article	New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site.
Academic Article	Surgical excision combined with autologous whole tumor cell vaccination is an effective therapy for murine neuroblastoma.
Academic Article	Decreased cytotoxic T cell activity generated by co-administration of PSA vaccine and CpG ODN is associated with increased tumor protection in a mouse model of prostate cancer.
Academic Article	Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients.
Academic Article	Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs.
Academic Article	From bugs to drugs: therapeutic immunomodulation with oligodeoxynucleotides containing CpG sequences from bacterial DNA.
Academic Article	Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells.
Academic Article	Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists.
Academic Article	Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma.
Academic Article	Dendritic cells pulsed or fused with AML cellular antigen provide comparable in vivo antitumor protective responses.
Academic Article	Uptake of oligodeoxyribonucleotides by lymphoid cells is heterogeneous and inducible.
Academic Article	Bacterial DNA does not increase serum corticosterone concentration or prevent increases induced by other stimuli.
Academic Article	Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides.
Academic Article	Immunostimulatory CpG oligodeoxynucleotide confers protection in a murine model of infection with Burkholderia pseudomallei.
Academic Article	Type I interferon is the primary regulator of inducible Ly-6C expression on T cells.
Academic Article	CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kappaB activation.
Academic Article	CpG oligodeoxynucleotide enhances tumor response to radiation.
Academic Article	Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12.
Academic Article	CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.
Academic Article	Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides.
Academic Article	Preferential nuclear compartmentalization of endogenous mink cell focus-forming-related retroviral transcripts.
Academic Article	Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
Academic Article	CpG motif identification for veterinary and laboratory species demonstrates that sequence recognition is highly conserved.
Academic Article	Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists.
Academic Article	CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge.
Academic Article	Reduction of antigen expression from DNA vaccines by coadministered oligodeoxynucleotides.
Academic Article	Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs.
Academic Article	Lactoferrin binds CpG-containing oligonucleotides and inhibits their immunostimulatory effects on human B cells.
Academic Article	Toll-like receptor 9 activation with CpG oligodeoxynucleotides for asthma therapy.
Academic Article	NIH conference. Systemic lupus erythematosus.
Academic Article	IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides.
Academic Article	Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine.
Academic Article	CpG DNA: a pathogenic factor in systemic lupus erythematosus?
Academic Article	Enhancement of infectious disease vaccines through TLR9-dependent recognition of CpG DNA.
Academic Article	Innate immune responses induced by classes of CpG oligodeoxynucleotides in ovine lymph node and blood mononuclear cells.
Academic Article	Association of murine lupus and thymic full-length endogenous retroviral expression maps to a bone marrow stem cell.
Academic Article	Divergent therapeutic and immunologic effects of oligodeoxynucleotides with distinct CpG motifs.
Academic Article	Lipopolysaccharide and CpG DNA synergize for tumor necrosis factor-alpha production through activation of NF-kappaB.
Academic Article	Theoretical and experimental approaches to generalized autoimmunity.
Academic Article	Biodegradable microspheres containing group B Streptococcus vaccine: immune response in mice.
Academic Article	Retroviruses and autoimmunity.
Academic Article	Distinct CpG oligonucleotide sequences activate human gamma delta T cells via interferon-alpha/-beta.
Academic Article	Comparison of CpG s-ODNs, chromatin immune complexes, and dsDNA fragment immune complexes in the TLR9-dependent activation of rheumatoid factor B cells.
Academic Article	Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation.
Academic Article	High mobility group B1 protein suppresses the human plasmacytoid dendritic cell response to TLR9 agonists.
Academic Article	FDA Approves Eteplirsen for Duchenne Muscular Dystrophy: The Next Chapter in the Eteplirsen Saga.
Academic Article	Analysis of thymic endogenous retroviral expression in murine lupus. Genetic and immune studies.
Academic Article	Increased utilization of polyreactive B cells during periods of generalized immune activation.
Academic Article	Systemic innate immune responses following intrapulmonary delivery of CpG oligodeoxynucleotides in sheep.
Academic Article	Phosphorothioate oligodeoxynucleotides: antisense or anti-protein?
Academic Article	Enhanced antibody responses elicited by a CpG adjuvant do not improve the protective effect of an aldrithiol-2-inactivated simian immunodeficiency virus therapeutic AIDS vaccine.
Academic Article	Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA.
Academic Article	CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide.
Academic Article	Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA.
Academic Article	Oligonucleotide uptake in human hematopoietic cells is increased in leukemia and is related to cellular activation.
Academic Article	Monocytes are required for optimum in vitro stimulation of bovine peripheral blood mononuclear cells by non-methylated CpG motifs.
Academic Article	Protection of Mice from Lethal Vaccinia Virus Infection by Vaccinia Virus Protein Subunits with a CpG Adjuvant.
Academic Article	Advancing Nucleic Acid Therapeutics by Setting Uniform Standards for Experimental Controls.
Academic Article	Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization.
Academic Article	Overcoming PD-1 Blockade Resistance with CpG-A Toll-Like Receptor 9 Agonist Vidutolimod in Patients with Metastatic Melanoma.
Academic Article	Considerations in the Preclinical Assessment of the Safety of Antisense Oligonucleotides.
Academic Article	Vidutolimod in Combination With Atezolizumab With and Without Radiation Therapy in Patients?With Programmed Cell Death Protein 1 or Programmed Death-Ligand 1 Blockade-Resistant Advanced NSCLC.
Academic Article	Xerna? TME Panel is a machine learning-based transcriptomic biomarker designed to predict therapeutic response in multiple cancers.
Academic Article	Combination Treatment of Intratumoral Vidutolimod, Radiosurgery, Nivolumab, and Ipilimumab for Microsatellite Stable Colorectal Carcinoma With Liver Metastases.
Academic Article	Neoadjuvant vidutolimod and nivolumab in high-risk resectable melanoma: A prospective phase II trial.

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