Item Type | Name |
Concept
|
Mice, Inbred CBA
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Mice, Inbred C3H
|
Concept
|
Mice, Inbred ICR
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Mice, Inbred A
|
Concept
|
Mice, Inbred Strains
|
Concept
|
Mice, Inbred NZB
|
Concept
|
Mice, Inbred DBA
|
Academic Article
|
CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection.
|
Academic Article
|
Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses.
|
Academic Article
|
Expression of an endogenous retroviral transcript is associated with murine lupus.
|
Academic Article
|
Role of mitogen-activated protein kinases in CpG DNA-mediated IL-10 and IL-12 production: central role of extracellular signal-regulated kinase in the negative feedback loop of the CpG DNA-mediated Th1 response.
|
Academic Article
|
Immunostimulatory oligodeoxynucleotides containing CpG motifs enhance the efficacy of monoclonal antibody therapy of lymphoma.
|
Academic Article
|
Bacterial DNA-induced NK cell IFN-gamma production is dependent on macrophage secretion of IL-12.
|
Academic Article
|
Biodistribution and metabolism of immunostimulatory oligodeoxynucleotide CPG 7909 in mouse and rat tissues following subcutaneous administration.
|
Academic Article
|
CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity.
|
Academic Article
|
Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization.
|
Academic Article
|
Interleukin-10 functions in vitro and in vivo to inhibit bacterial DNA-induced secretion of interleukin-12.
|
Academic Article
|
Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma.
|
Academic Article
|
CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen.
|
Academic Article
|
CpG oligodeoxyribonucleotides rescue mature spleen B cells from spontaneous apoptosis and promote cell cycle entry.
|
Academic Article
|
CpG oligonucleotides enhance the tumor antigen-specific immune response of a granulocyte macrophage colony-stimulating factor-based vaccine strategy in neuroblastoma.
|
Academic Article
|
Rapid immune activation by CpG motifs in bacterial DNA. Systemic induction of IL-6 transcription through an antioxidant-sensitive pathway.
|
Academic Article
|
CpG oligodeoxynucleotides augment the murine immune response to the Yersinia pestis F1-V vaccine in bubonic and pneumonic models of plague.
|
Academic Article
|
Induction of CD8 T-cell-specific systemic and mucosal immunity against herpes simplex virus with CpG-peptide complexes.
|
Academic Article
|
B cells express Ly-6C in a Th1 but not Th2 cytokine environment.
|
Academic Article
|
Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine.
|
Academic Article
|
Comparative analysis of murine marrow-derived dendritic cells generated by Flt3L or GM-CSF/IL-4 and matured with immune stimulatory agents on the in vivo induction of antileukemia responses.
|
Academic Article
|
Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself.
|
Academic Article
|
CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species.
|
Academic Article
|
TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells.
|
Academic Article
|
CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus.
|
Academic Article
|
Synergy between CpG- or non-CpG DNA and specific antigen for B cell activation.
|
Academic Article
|
Cyclosporin A enhances IL-12 production by CpG motifs in bacterial DNA and synthetic oligodeoxynucleotides.
|
Academic Article
|
CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice.
|
Academic Article
|
CpG oligonucleotides protect against Venezuelan equine encephalitis virus infection in a route-dependent manner.
|
Academic Article
|
CpG oligodeoxynucleotide enhances immunity against blood-stage malaria infection in mice parenterally immunized with a yeast-expressed 19 kDa carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (MSP1(19)) formulated in oil-based Montanides.
|
Academic Article
|
Stimulation via Toll-like receptor 9 reduces Cryptococcus neoformans-induced pulmonary inflammation in an IL-12-dependent manner.
|
Academic Article
|
A role for endogenous retroviral sequences in the regulation of lymphocyte activation.
|
Academic Article
|
Increased expression of novel full-length endogenous mink cell focus-forming-related transcripts in autoimmune mouse strains.
|
Academic Article
|
Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy.
|
Academic Article
|
CpG-DNA protects against a lethal orthopoxvirus infection in a murine model.
|
Academic Article
|
CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract.
|
Academic Article
|
Combining vaccination and postexposure CpG therapy provides optimal protection against lethal sepsis in a biodefense model of human melioidosis.
|
Academic Article
|
CpG oligodeoxynucleotides down-regulate macrophage class II MHC antigen processing.
|
Academic Article
|
Oral pretreatment of mice with CpG DNA reduces susceptibility to oral or intraperitoneal challenge with virulent Listeria monocytogenes.
|
Academic Article
|
CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma.
|
Academic Article
|
Inhibitory oligonucleotides block the induction of AP-1 transcription factor by stimulatory CpG oligonucleotides in B cells.
|
Academic Article
|
CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma.
|
Academic Article
|
CpG DNA: trigger of sepsis, mediator of protection, or both?
|
Academic Article
|
Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor.
|
Academic Article
|
CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic mice.
|
Academic Article
|
Immunostimulatory CpG oligonucleotides enhance the immune response of anti-idiotype vaccine that mimics carcinoembryonic antigen.
|
Academic Article
|
CpG oligodeoxynucleotides can circumvent the Th2 polarization of neonatal responses to vaccines but may fail to fully redirect Th2 responses established by neonatal priming.
|
Academic Article
|
Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers.
|
Academic Article
|
Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms.
|
Academic Article
|
Multiple endogenous xenotropic and mink cell focus-forming murine leukemia virus-related transcripts are induced by polyclonal immune activators.
|
Academic Article
|
Immunostimulatory potential of silencing RNAs can be mediated by a non-uridine-rich toll-like receptor 7 motif.
|
Academic Article
|
Bacterial DNA or oligonucleotides containing unmethylated CpG motifs can minimize lipopolysaccharide-induced inflammation in the lower respiratory tract through an IL-12-dependent pathway.
|
Academic Article
|
A novel class of immune-stimulatory CpG oligodeoxynucleotides unifies high potency in type I interferon induction with preferred structural properties.
|
Academic Article
|
Induction and regulation of Th1-inducing cytokines by bacterial DNA, lipopolysaccharide, and heat-inactivated bacteria.
|
Academic Article
|
Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo.
|
Academic Article
|
Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses.
|
Academic Article
|
Administration of a phosphorothioate oligonucleotide antisense to murine endogenous retroviral MCF env causes immune effects in vivo in a sequence-specific manner.
|
Academic Article
|
A CpG oligonucleotide can protect mice from a low aerosol challenge dose of Burkholderia mallei.
|
Academic Article
|
CpG oligodeoxynucleotide and Montanide ISA 51 adjuvant combination enhanced the protective efficacy of a subunit malaria vaccine.
|
Academic Article
|
APC stimulated by CpG oligodeoxynucleotide enhance activation of MHC class I-restricted T cells.
|
Academic Article
|
Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo.
|
Academic Article
|
Effect of cyclophosphamide, total body irradiation, and zidovudine on retrovirus proliferation and disease progression in murine AIDS.
|
Academic Article
|
CpG DNA is an effective oral adjuvant to protein antigens in mice.
|
Academic Article
|
TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.
|
Academic Article
|
CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms.
|
Academic Article
|
P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides.
|
Academic Article
|
Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens.
|
Academic Article
|
Chronic ethanol ingestion by mice increases expression of CD80 and CD86 by activated macrophages.
|
Academic Article
|
Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.
|
Academic Article
|
NK cells activated in vivo by bacterial DNA control the intracellular growth of Francisella tularensis LVS.
|
Academic Article
|
CpG DNA induces cyclooxygenase-2 expression and prostaglandin production.
|
Academic Article
|
Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy.
|
Academic Article
|
Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment.
|
Academic Article
|
Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila.
|
Academic Article
|
CpG motifs in bacterial DNA trigger direct B-cell activation.
|
Academic Article
|
Stage-specific oligonucleotide uptake in murine bone marrow B-cell precursors.
|
Academic Article
|
Nonspecific suppression of [3H]thymidine incorporation by "control" oligonucleotides.
|
Academic Article
|
A combination of Flt3 ligand cDNA and CpG ODN as nasal adjuvant elicits NALT dendritic cells for prolonged mucosal immunity.
|
Academic Article
|
Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway.
|
Academic Article
|
Timing of immunosuppression in the natural history of autoimmune diseases.
|
Academic Article
|
Decreased cytotoxic T cell activity generated by co-administration of PSA vaccine and CpG ODN is associated with increased tumor protection in a mouse model of prostate cancer.
|
Academic Article
|
Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs.
|
Academic Article
|
Uptake of oligodeoxyribonucleotides by lymphoid cells is heterogeneous and inducible.
|
Academic Article
|
Bacterial DNA does not increase serum corticosterone concentration or prevent increases induced by other stimuli.
|
Academic Article
|
Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides.
|
Academic Article
|
Immunostimulatory CpG oligodeoxynucleotide confers protection in a murine model of infection with Burkholderia pseudomallei.
|
Academic Article
|
Type I interferon is the primary regulator of inducible Ly-6C expression on T cells.
|
Academic Article
|
CpG oligodeoxynucleotide enhances tumor response to radiation.
|
Academic Article
|
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.
|
Academic Article
|
Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides.
|
Academic Article
|
CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge.
|
Academic Article
|
Reduction of antigen expression from DNA vaccines by coadministered oligodeoxynucleotides.
|
Academic Article
|
Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs.
|
Academic Article
|
IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides.
|
Academic Article
|
Association of murine lupus and thymic full-length endogenous retroviral expression maps to a bone marrow stem cell.
|
Academic Article
|
Divergent therapeutic and immunologic effects of oligodeoxynucleotides with distinct CpG motifs.
|
Academic Article
|
Biodegradable microspheres containing group B Streptococcus vaccine: immune response in mice.
|
Academic Article
|
Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation.
|
Academic Article
|
Analysis of thymic endogenous retroviral expression in murine lupus. Genetic and immune studies.
|
Academic Article
|
Increased utilization of polyreactive B cells during periods of generalized immune activation.
|
Academic Article
|
Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA.
|
Academic Article
|
CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide.
|
Academic Article
|
Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA.
|