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One or more keywords matched the following items that are connected to Krieg, Arthur
Item TypeName
Concept Mice, Inbred CBA
Concept Mice, Inbred BALB C
Concept Mice, Inbred C3H
Concept Mice, Inbred ICR
Concept Mice, Inbred C57BL
Concept Mice, Inbred A
Concept Mice, Inbred Strains
Concept Mice, Inbred NZB
Concept Mice, Inbred DBA
Academic Article CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection.
Academic Article Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses.
Academic Article Expression of an endogenous retroviral transcript is associated with murine lupus.
Academic Article Role of mitogen-activated protein kinases in CpG DNA-mediated IL-10 and IL-12 production: central role of extracellular signal-regulated kinase in the negative feedback loop of the CpG DNA-mediated Th1 response.
Academic Article Immunostimulatory oligodeoxynucleotides containing CpG motifs enhance the efficacy of monoclonal antibody therapy of lymphoma.
Academic Article Bacterial DNA-induced NK cell IFN-gamma production is dependent on macrophage secretion of IL-12.
Academic Article Biodistribution and metabolism of immunostimulatory oligodeoxynucleotide CPG 7909 in mouse and rat tissues following subcutaneous administration.
Academic Article CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity.
Academic Article Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization.
Academic Article Interleukin-10 functions in vitro and in vivo to inhibit bacterial DNA-induced secretion of interleukin-12.
Academic Article Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma.
Academic Article CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen.
Academic Article CpG oligodeoxyribonucleotides rescue mature spleen B cells from spontaneous apoptosis and promote cell cycle entry.
Academic Article CpG oligonucleotides enhance the tumor antigen-specific immune response of a granulocyte macrophage colony-stimulating factor-based vaccine strategy in neuroblastoma.
Academic Article Rapid immune activation by CpG motifs in bacterial DNA. Systemic induction of IL-6 transcription through an antioxidant-sensitive pathway.
Academic Article CpG oligodeoxynucleotides augment the murine immune response to the Yersinia pestis F1-V vaccine in bubonic and pneumonic models of plague.
Academic Article Induction of CD8 T-cell-specific systemic and mucosal immunity against herpes simplex virus with CpG-peptide complexes.
Academic Article B cells express Ly-6C in a Th1 but not Th2 cytokine environment.
Academic Article Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine.
Academic Article Comparative analysis of murine marrow-derived dendritic cells generated by Flt3L or GM-CSF/IL-4 and matured with immune stimulatory agents on the in vivo induction of antileukemia responses.
Academic Article Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself.
Academic Article CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species.
Academic Article TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells.
Academic Article CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus.
Academic Article Synergy between CpG- or non-CpG DNA and specific antigen for B cell activation.
Academic Article Cyclosporin A enhances IL-12 production by CpG motifs in bacterial DNA and synthetic oligodeoxynucleotides.
Academic Article CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice.
Academic Article CpG oligonucleotides protect against Venezuelan equine encephalitis virus infection in a route-dependent manner.
Academic Article CpG oligodeoxynucleotide enhances immunity against blood-stage malaria infection in mice parenterally immunized with a yeast-expressed 19 kDa carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (MSP1(19)) formulated in oil-based Montanides.
Academic Article Stimulation via Toll-like receptor 9 reduces Cryptococcus neoformans-induced pulmonary inflammation in an IL-12-dependent manner.
Academic Article A role for endogenous retroviral sequences in the regulation of lymphocyte activation.
Academic Article Increased expression of novel full-length endogenous mink cell focus-forming-related transcripts in autoimmune mouse strains.
Academic Article Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy.
Academic Article CpG-DNA protects against a lethal orthopoxvirus infection in a murine model.
Academic Article CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract.
Academic Article Combining vaccination and postexposure CpG therapy provides optimal protection against lethal sepsis in a biodefense model of human melioidosis.
Academic Article CpG oligodeoxynucleotides down-regulate macrophage class II MHC antigen processing.
Academic Article Oral pretreatment of mice with CpG DNA reduces susceptibility to oral or intraperitoneal challenge with virulent Listeria monocytogenes.
Academic Article CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma.
Academic Article Inhibitory oligonucleotides block the induction of AP-1 transcription factor by stimulatory CpG oligonucleotides in B cells.
Academic Article CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma.
Academic Article CpG DNA: trigger of sepsis, mediator of protection, or both?
Academic Article Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor.
Academic Article CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic mice.
Academic Article Immunostimulatory CpG oligonucleotides enhance the immune response of anti-idiotype vaccine that mimics carcinoembryonic antigen.
Academic Article CpG oligodeoxynucleotides can circumvent the Th2 polarization of neonatal responses to vaccines but may fail to fully redirect Th2 responses established by neonatal priming.
Academic Article Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers.
Academic Article Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms.
Academic Article Multiple endogenous xenotropic and mink cell focus-forming murine leukemia virus-related transcripts are induced by polyclonal immune activators.
Academic Article Immunostimulatory potential of silencing RNAs can be mediated by a non-uridine-rich toll-like receptor 7 motif.
Academic Article Bacterial DNA or oligonucleotides containing unmethylated CpG motifs can minimize lipopolysaccharide-induced inflammation in the lower respiratory tract through an IL-12-dependent pathway.
Academic Article A novel class of immune-stimulatory CpG oligodeoxynucleotides unifies high potency in type I interferon induction with preferred structural properties.
Academic Article Induction and regulation of Th1-inducing cytokines by bacterial DNA, lipopolysaccharide, and heat-inactivated bacteria.
Academic Article Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo.
Academic Article Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses.
Academic Article Administration of a phosphorothioate oligonucleotide antisense to murine endogenous retroviral MCF env causes immune effects in vivo in a sequence-specific manner.
Academic Article A CpG oligonucleotide can protect mice from a low aerosol challenge dose of Burkholderia mallei.
Academic Article CpG oligodeoxynucleotide and Montanide ISA 51 adjuvant combination enhanced the protective efficacy of a subunit malaria vaccine.
Academic Article APC stimulated by CpG oligodeoxynucleotide enhance activation of MHC class I-restricted T cells.
Academic Article Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo.
Academic Article Effect of cyclophosphamide, total body irradiation, and zidovudine on retrovirus proliferation and disease progression in murine AIDS.
Academic Article CpG DNA is an effective oral adjuvant to protein antigens in mice.
Academic Article TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.
Academic Article CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms.
Academic Article P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides.
Academic Article Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens.
Academic Article Chronic ethanol ingestion by mice increases expression of CD80 and CD86 by activated macrophages.
Academic Article Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.
Academic Article NK cells activated in vivo by bacterial DNA control the intracellular growth of Francisella tularensis LVS.
Academic Article CpG DNA induces cyclooxygenase-2 expression and prostaglandin production.
Academic Article Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy.
Academic Article Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment.
Academic Article Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila.
Academic Article CpG motifs in bacterial DNA trigger direct B-cell activation.
Academic Article Stage-specific oligonucleotide uptake in murine bone marrow B-cell precursors.
Academic Article Nonspecific suppression of [3H]thymidine incorporation by "control" oligonucleotides.
Academic Article A combination of Flt3 ligand cDNA and CpG ODN as nasal adjuvant elicits NALT dendritic cells for prolonged mucosal immunity.
Academic Article Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway.
Academic Article Timing of immunosuppression in the natural history of autoimmune diseases.
Academic Article Decreased cytotoxic T cell activity generated by co-administration of PSA vaccine and CpG ODN is associated with increased tumor protection in a mouse model of prostate cancer.
Academic Article Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs.
Academic Article Uptake of oligodeoxyribonucleotides by lymphoid cells is heterogeneous and inducible.
Academic Article Bacterial DNA does not increase serum corticosterone concentration or prevent increases induced by other stimuli.
Academic Article Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides.
Academic Article Immunostimulatory CpG oligodeoxynucleotide confers protection in a murine model of infection with Burkholderia pseudomallei.
Academic Article Type I interferon is the primary regulator of inducible Ly-6C expression on T cells.
Academic Article CpG oligodeoxynucleotide enhances tumor response to radiation.
Academic Article CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.
Academic Article Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides.
Academic Article CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge.
Academic Article Reduction of antigen expression from DNA vaccines by coadministered oligodeoxynucleotides.
Academic Article Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs.
Academic Article IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides.
Academic Article Association of murine lupus and thymic full-length endogenous retroviral expression maps to a bone marrow stem cell.
Academic Article Divergent therapeutic and immunologic effects of oligodeoxynucleotides with distinct CpG motifs.
Academic Article Biodegradable microspheres containing group B Streptococcus vaccine: immune response in mice.
Academic Article Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation.
Academic Article Analysis of thymic endogenous retroviral expression in murine lupus. Genetic and immune studies.
Academic Article Increased utilization of polyreactive B cells during periods of generalized immune activation.
Academic Article Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA.
Academic Article CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide.
Academic Article Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA.
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  • Mice Inbred A