Item Type | Name |
Concept
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Toll-Like Receptors
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Concept
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Toll-Like Receptor 4
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Concept
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Toll-Like Receptor 9
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Concept
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Toll-Like Receptor 2
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Concept
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Toll-Like Receptor 7
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Concept
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Toll-Like Receptor 1
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Concept
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Toll-Like Receptor 8
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Academic Article
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C-Class CpG ODN: sequence requirements and characterization of immunostimulatory activities on mRNA level.
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Academic Article
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Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses.
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Academic Article
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Early development of the Toll-like receptor 9 agonist, PF-3512676, for the treatment of patients with advanced cancers.
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Academic Article
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From A to Z on CpG.
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Academic Article
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CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B HBV vaccine in healthy adults: a double-blind phase I/II study.
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Academic Article
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Induction of systemic TH1-like innate immunity in normal volunteers following subcutaneous but not intravenous administration of CPG 7909, a synthetic B-class CpG oligodeoxynucleotide TLR9 agonist.
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Academic Article
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Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals.
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Academic Article
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A role for Toll in autoimmunity.
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Academic Article
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Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma.
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Academic Article
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Development of TLR9 agonists for cancer therapy.
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Academic Article
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Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoid dendritic cells.
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Academic Article
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Toll-free vaccines?
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Academic Article
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CpG oligodeoxynucleotides augment the murine immune response to the Yersinia pestis F1-V vaccine in bubonic and pneumonic models of plague.
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Academic Article
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Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848.
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Academic Article
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CpG oligodeoxynucleotides stimulate IFN-gamma-inducible protein-10 production in human B cells.
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Academic Article
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Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine.
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Academic Article
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Antiinfective applications of toll-like receptor 9 agonists.
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Academic Article
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Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself.
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Academic Article
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Safety, pharmacokinetics and immune effects in normal volunteers of CPG 10101 (ACTILON), an investigational synthetic toll-like receptor 9 agonist.
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Academic Article
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TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells.
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Academic Article
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Phase I trial of toll-like receptor 9 agonist PF-3512676 with and following rituximab in patients with recurrent indolent and aggressive non Hodgkin's lymphoma.
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Academic Article
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The toll of too much TLR7.
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Academic Article
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CpG motifs: the active ingredient in bacterial extracts?
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Academic Article
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Stimulation via Toll-like receptor 9 reduces Cryptococcus neoformans-induced pulmonary inflammation in an IL-12-dependent manner.
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Academic Article
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Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy.
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Academic Article
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TLR9 and DNA 'feel' RAGE.
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Academic Article
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Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands.
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Academic Article
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Attenuated cytokine responses in porcine lymph node cells stimulated with CpG DNA are associated with low frequency of IFNalpha-producing cells and TLR9 mRNA expression.
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Academic Article
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Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity.
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Academic Article
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Immunostimulatory potential of silencing RNAs can be mediated by a non-uridine-rich toll-like receptor 7 motif.
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Academic Article
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Toll-like receptor 9 (TLR9) agonists in the treatment of cancer.
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Academic Article
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The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques.
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Academic Article
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Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery.
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Academic Article
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Immunology. The toll of cathepsin K deficiency.
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Academic Article
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Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8.
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Academic Article
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Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses.
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Academic Article
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Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides.
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Academic Article
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TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.
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Academic Article
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Therapeutic potential of Toll-like receptor 9 activation.
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Academic Article
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Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells.
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Academic Article
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Randomized phase II trial of a toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer.
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Academic Article
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Immunopharmacology of CpG oligodeoxynucleotides and ribavirin.
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Academic Article
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Paclitaxel reduces regulatory T cell numbers and inhibitory function and enhances the anti-tumor effects of the TLR9 agonist PF-3512676 in the mouse.
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Academic Article
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Now I know my CpGs.
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Academic Article
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Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.
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Academic Article
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Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment.
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Academic Article
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Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila.
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Academic Article
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Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs.
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Academic Article
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Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities.
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Academic Article
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Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides.
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Academic Article
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Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway.
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Academic Article
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CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands.
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Academic Article
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Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists.
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Academic Article
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Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12.
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Academic Article
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Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists.
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Academic Article
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Toll-like receptor 9 activation with CpG oligodeoxynucleotides for asthma therapy.
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Academic Article
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Enhancement of infectious disease vaccines through TLR9-dependent recognition of CpG DNA.
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Academic Article
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Comparison of CpG s-ODNs, chromatin immune complexes, and dsDNA fragment immune complexes in the TLR9-dependent activation of rheumatoid factor B cells.
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Academic Article
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Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation.
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Academic Article
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High mobility group B1 protein suppresses the human plasmacytoid dendritic cell response to TLR9 agonists.
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Academic Article
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Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization.
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Academic Article
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Overcoming PD-1 Blockade Resistance with CpG-A Toll-Like Receptor 9 Agonist Vidutolimod in Patients with Metastatic Melanoma.
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