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One or more keywords matched the following properties of Shohet, Jason
keywords Myc oncogenes
One or more keywords matched the following items that are connected to Shohet, Jason
Item TypeName
Concept Oncogenes
Concept Oncogene Proteins
Concept Proto-Oncogene Proteins c-mdm2
Concept Proto-Oncogene Proteins c-akt
Concept Proto-Oncogene Proteins c-myc
Concept Proto-Oncogene Proteins
Academic Article p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy.
Academic Article MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma.
Academic Article WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma.
Academic Article The role of histone demethylase KDM4B in Myc signaling in neuroblastoma.
Academic Article Redefining functional MYCN gene signatures in neuroblastoma.
Academic Article MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma.
Academic Article G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic.
Academic Article Gene profiling of high risk neuroblastoma.
Academic Article Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis.
Academic Article MDM2 as a critical effector of the MYCN oncogene in tumorigenesis.
Academic Article MDM2 as MYCN transcriptional target: implications for neuroblastoma pathogenesis.
Academic Article MYCN-directed centrosome amplification requires MDM2-mediated suppression of p53 activity in neuroblastoma cells.
Academic Article A genome-wide search for promoters that respond to increased MYCN reveals both new oncogenic and tumor suppressor microRNAs associated with aggressive neuroblastoma.
Academic Article The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma.
Academic Article MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death.
Academic Article Mdm2 deficiency suppresses MYCN-Driven neuroblastoma tumorigenesis in vivo.
Academic Article Targeted molecular therapy for neuroblastoma: the ARF/MDM2/p53 axis.
Academic Article Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma.
Academic Article MDM2-p53 interaction in paediatric solid tumours: preclinical rationale, biomarkers and resistance.
Academic Article A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma.
Academic Article KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma.
Concept N-Myc Proto-Oncogene Protein
Academic Article PRMT5 activates AKT via methylation to promote tumor metastasis.
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  • Oncogenes