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Grigorieff, Nikolaus

One or more keywords matched the following items that are connected to Grigorieff, Nikolaus

Item Type	Name
Academic Article	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
Academic Article	Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Academic Article	Three-dimensional structure of C complex spliceosomes by electron microscopy.
Academic Article	The three-dimensional arcitecture of the EJC core.
Concept	RNA Polymerase I
Concept	Coenzymes
Concept	Ribosome Subunits
Concept	Gallium
Concept	Temperature
Concept	Wiskott-Aldrich Syndrome Protein
Concept	Imaging, Three-Dimensional
Concept	Mycobacterium tuberculosis
Concept	Data Interpretation, Statistical
Concept	Software
Concept	Ion Channel Gating
Concept	Mitochondria
Concept	Carbon
Concept	Introns
Concept	HeLa Cells
Concept	HSC70 Heat-Shock Proteins
Concept	Drug Design
Concept	Actins
Concept	Gene Expression
Concept	Drosophila melanogaster
Concept	COS Cells
Concept	Membrane Potentials
Concept	DNA Helicases
Concept	Caenorhabditis elegans
Concept	Information Storage and Retrieval
Concept	HSP70 Heat-Shock Proteins
Concept	Lens Capsule, Crystalline
Concept	Calcium Channels
Concept	Antibodies, Neutralizing
Concept	Cricetinae
Concept	Frameshifting, Ribosomal
Concept	Negative Staining
Concept	NIH 3T3 Cells
Concept	Software Design
Concept	Clathrin Heavy Chains
Concept	Open Reading Frames
Concept	Coated Vesicles
Concept	Computer Simulation
Concept	Carrier Proteins
Concept	Ribosome Subunits, Large, Bacterial
Concept	Electrophysiology
Concept	Adenosine Triphosphate
Concept	Protein Biosynthesis
Concept	Amino Acid Sequence
Concept	Molecular Dynamics Simulation
Concept	Algorithms
Concept	Peptide Elongation Factor 2
Concept	Calcium
Concept	Water
Concept	Antibodies, Viral
Concept	Single-Chain Antibodies
Concept	Kinetochores
Concept	Molybdenum
Concept	Bacteriorhodopsins
Concept	Adenomatous Polyposis Coli Protein
Concept	Protein Interaction Domains and Motifs
Concept	Microtubules
Concept	Spliceosomes
Concept	Mitosis
Concept	Iron
Concept	DNA, Cruciform
Concept	Purple Membrane
Concept	Chromatography, Gel
Concept	Actin Capping Proteins
Concept	Cysteine
Concept	Image Enhancement
Concept	N-Ethylmaleimide-Sensitive Proteins
Concept	Electrons
Concept	Transcription, Genetic
Concept	Static Electricity
Concept	HIV Envelope Protein gp120
Concept	Exons
Concept	Cattle
Concept	Fourier Analysis
Concept	Codon
Concept	Deoxycholic Acid
Concept	Transferrin
Concept	Computational Biology
Concept	Tissue Embedding
Concept	Clathrin-Coated Vesicles
Concept	Light
Concept	Ribosome Subunits, Small, Bacterial
Concept	Capsid
Concept	Chickens
Concept	RNA Splice Sites
Concept	DNA, Bacterial
Concept	Escherichia coli
Concept	Profilins
Concept	DEAD-box RNA Helicases
Concept	Ribonuclease H
Concept	Crystallography
Concept	Bacteriophage lambda
Concept	Zinc
Concept	Catalytic Domain
Concept	GTP Phosphohydrolases
Concept	DNA Damage
Concept	Cell Membrane
Concept	Crystallography, X-Ray
Concept	Escherichia coli Proteins
Concept	Detergents
Concept	ATP-Binding Cassette Transporters
Concept	Green Fluorescent Proteins
Concept	Vaccines, Synthetic
Concept	Peptide Elongation Factor G
Concept	Gold
Concept	Calcium-Binding Proteins
Concept	Capsid Proteins
Concept	Tubulin
Concept	DNA Polymerase III
Concept	Alzheimer Disease
Concept	Calcium Channels, L-Type
Concept	Mitochondrial Proton-Translocating ATPases
Concept	Papillomaviridae
Concept	Models, Structural
Concept	Freezing
Concept	Ribosome Subunits, Large
Concept	NAD
Concept	Microfilament Proteins
Concept	Caliciviridae Infections
Concept	Actin-Related Protein 2
Concept	Electron Transport
Concept	Data Display
Concept	Anticodon
Concept	Sequence Homology, Amino Acid
Concept	Staining and Labeling
Concept	Image Processing, Computer-Assisted
Concept	Receptors, N-Methyl-D-Aspartate
Concept	Ions
Concept	Proteomics
Concept	HIV Antibodies
Concept	Clathrin
Concept	Cell Line
Concept	Adenosine Triphosphatases
Concept	Actin-Related Protein 3
Concept	Sulfur
Concept	beta-Galactosidase
Concept	DNA-Directed RNA Polymerases
Concept	Ryanodine Receptor Calcium Release Channel
Concept	DNA Repair
Concept	Molecular Motor Proteins
Concept	Bayes Theorem
Concept	Virion
Concept	Sulfates
Concept	Ice
Concept	HIV Envelope Protein gp41
Concept	Hydrogen Bonding
Concept	Amyloid beta-Peptides
Concept	Peptide Elongation Factor Tu
Concept	Actin Cytoskeleton
Concept	Molecular Sequence Data
Concept	Electron Microscope Tomography
Concept	Ribosomes
Academic Article	Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Academic Article	Structures of yeast 80S ribosome-tRNA complexes in the rotated and nonrotated conformations.
Academic Article	Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Academic Article	Ribosome?RelA structures reveal the mechanism of stringent response activation.
Academic Article	Mechanism of ribosome rescue by ArfA and RF2.
Academic Article	Ensemble cryo-EM elucidates the mechanism of translation fidelity.
Academic Article	Electron-crystallographic refinement of the structure of bacteriorhodopsin.
Academic Article	Clathrin coats at 21 A resolution: a cellular assembly designed to recycle multiple membrane receptors.
Academic Article	Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 A in ice.
Academic Article	Structure of the respiratory NADH:ubiquinone oxidoreductase (complex I)
Academic Article	Resolution measurement in structures derived from single particles.
Academic Article	Electron diffraction of a bacterial ClC-type chloride channel.
Academic Article	Projection structure of a ClC-type chloride channel at 6.5 A resolution.
Academic Article	Three-dimensional structure of a voltage-gated potassium channel at 2.5 nm resolution.
Academic Article	A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening.
Academic Article	Molecular Machines: putting the pieces together.
Academic Article	Accurate determination of local defocus and specimen tilt in electron microscopy.
Academic Article	Ito channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2.
Academic Article	Electron cryomicroscopy structure of N-ethyl maleimide sensitive factor at 11 A resolution.
Academic Article	Three-dimensional structure of I(to); Kv4.2-KChIP2 ion channels by electron microscopy at 21 Angstrom resolution.
Academic Article	Molecular model for a complete clathrin lattice from electron cryomicroscopy.
Academic Article	Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating.
Academic Article	Visualization of the domain structure of an L-type Ca2+ channel using electron cryo-microscopy.
Academic Article	Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.
Academic Article	Low-resolution structure refinement in electron microscopy.
Academic Article	Conformational changes in the Arp2/3 complex leading to actin nucleation.
Academic Article	CTFFIND4: Fast and accurate defocus estimation from electron micrographs.
Academic Article	Peptide dimer structure in an A?(1-42) fibril visualized with cryo-EM.
Academic Article	Physical basis of amyloid fibril polymorphism.
Academic Article	Atomic Resolution Cryo-EM Structure of ?-Galactosidase.
Academic Article	Single-protein detection in crowded molecular environments in cryo-EM images.
Academic Article	CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface.
Academic Article	Expression, purification, and contaminant detection for structural studies of Ralstonia metallidurance ClC protein rm1.
Academic Article	Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation.
Academic Article	cisTEM, user-friendly software for single-particle image processing.
Academic Article	Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Academic Article	Lipid location in deoxycholate-treated purple membrane at 2.6 A.
Academic Article	Increased sulfate uptake by E. coli overexpressing the SLC26-related SulP protein Rv1739c from Mycobacterium tuberculosis.
Academic Article	Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly.
Academic Article	Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.
Academic Article	Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Academic Article	High-resolution electron microscopy of helical specimens: a fresh look at tobacco mosaic virus.
Academic Article	A dose-rate effect in single-particle electron microscopy.
Academic Article	Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction.
Academic Article	Noise bias in the refinement of structures derived from single particles.
Academic Article	Ewald sphere correction for single-particle electron microscopy.
Academic Article	Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils.
Academic Article	Single particle reconstructions of the transferrin-transferrin receptor complex obtained with different specimen preparation techniques.
Academic Article	SIGNATURE: a single-particle selection system for molecular electron microscopy.
Academic Article	Actin filament labels for localizing protein components in large complexes viewed by electron microscopy.
Academic Article	Pentameric assembly of potassium channel tetramerization domain-containing protein 5.
Academic Article	Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM.
Academic Article	Structural polymorphism of Alzheimer Abeta and other amyloid fibrils.
Academic Article	Comparison of Alzheimer Abeta(1-40) and Abeta(1-42) amyloid fibrils reveals similar protofilament structures.
Academic Article	Untitled Publication
Academic Article	The Ndc80 kinetochore complex forms oligomeric arrays along microtubules.
Academic Article	FREALIGN: high-resolution refinement of single particle structures.
Academic Article	Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy.
Academic Article	Quaternary structure of a mature amyloid fibril from Alzheimer's Abeta(1-40) peptide.
Academic Article	Ab initio resolution measurement for single particle structures.
Academic Article	Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1.
Academic Article	Atomic model of an infectious rotavirus particle.
Academic Article	A maximum likelihood approach to two-dimensional crystals.
Academic Article	Paired beta-sheet structure of an Abeta(1-40) amyloid fibril revealed by electron microscopy.
Academic Article	Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopy.
Academic Article	Recent progress in understanding Alzheimer's ?-amyloid structures.
Academic Article	An adaptation of the Wiener filter suitable for analyzing images of isolated single particles.
Academic Article	Beam-induced motion of vitrified specimen on holey carbon film.
Academic Article	Nanoscale flexibility parameters of Alzheimer amyloid fibrils determined by electron cryo-microscopy.
Academic Article	Outcome of the first electron microscopy validation task force meeting.
Academic Article	Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface.
Academic Article	Optimal noise reduction in 3D reconstructions of single particles using a volume-normalized filter.
Academic Article	Maturation in action: CryoEM study of a viral capsid caught during expansion.
Academic Article	Direct detection pays off for electron cryo-microscopy.
Academic Article	Likelihood-based classification of cryo-EM images using FREALIGN.
Academic Article	Frealix: model-based refinement of helical filament structures from electron micrographs.
Academic Article	Subunit interactions in bovine papillomavirus.
Academic Article	GPU-enabled FREALIGN: accelerating single particle 3D reconstruction and refinement in Fourier space on graphics processors.
Academic Article	Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy.
Academic Article	A primer to single-particle cryo-electron microscopy.
Academic Article	Structural complexity of a composite amyloid fibril.
Academic Article	Automatic estimation and correction of anisotropic magnification distortion in electron microscopes.
Academic Article	Evaluation of super-resolution performance of the K2 electron-counting camera using 2D crystals of aquaporin-0.
Academic Article	Measuring the optimal exposure for single particle cryo-EM using a 2.6 ? reconstruction of rotavirus VP6.
Academic Article	Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.
Academic Article	Movies of ice-embedded particles enhance resolution in electron cryo-microscopy.
Academic Article	Interplay of DNA repair with transcription: from structures to mechanisms.
Academic Article	Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles.
Academic Article	Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril.
Academic Article	Frealign: An Exploratory Tool for Single-Particle Cryo-EM.
Academic Article	Activation of NMDA receptors and the mechanism of inhibition by ifenprodil.
Academic Article	Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction.
Academic Article	Structure of the transporter associated with antigen processing trapped by herpes simplex virus.
Academic Article	Structure of RNA polymerase bound to ribosomal 30S subunit.
Academic Article	Quantitative characterization of electron detectors for transmission electron microscopy.
Academic Article	Conformational States of a Soluble, Uncleaved HIV-1 Envelope Trimer.
Academic Article	Analysis of discrete local variability and structural covariance in macromolecular assemblies using Cryo-EM and focused classification.
Academic Article	Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids.
Academic Article	High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Academic Article	In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase.
Academic Article	In situ structure determination at nanometer resolution using TYGRESS.
Academic Article	Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor.
Academic Article	Structure and assembly of calcium homeostasis modulator proteins.
Academic Article	Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins.
Academic Article	mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.
Academic Article	Locating macromolecular assemblies in cells by 2D template matching with cisTEM.
Academic Article	Cryo-TEM simulations of amorphous radiation-sensitive samples using multislice wave propagation.
Concept	Internal Ribosome Entry Sites
Concept	Protein Domains
Concept	Spastin
Concept	Katanin
Concept	HEK293 Cells
Concept	Molecular Sequence Annotation
Academic Article	In situ single particle classification reveals distinct 60S maturation intermediates in cells.
Academic Article	Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections.
Academic Article	From primordial clocks to circadian oscillators.
Academic Article	Quantification of gallium cryo-FIB milling damage in biological lamellae.
Academic Article	Exploring the Limits of 2D Template Matching for Detecting Targets in Cellular Cryo-EM Images.
Academic Article	Baited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias.
Academic Article	Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryo-electron tomography.
Academic Article	CTFFIND5 provides improved insight into quality, tilt, and thickness of TEM samples.
Academic Article	A new statistical metric for robust target detection in cryo-EM using 2D template matching.

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