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Shen, Kuang

One or more keywords matched the following items that are connected to Shen, Kuang

Item Type	Name
Concept	GTP Phosphohydrolase Activators
Concept	GTP Phosphohydrolases
Concept	GTPase-Activating Proteins
Academic Article	Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex.
Academic Article	The structural basis of FtsY recruitment and GTPase activation by SRP RNA.
Academic Article	Activated GTPase movement on an RNA scaffold drives co-translational protein targeting.
Academic Article	The crystal structure of the signal recognition particle in complex with its receptor.
Academic Article	Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability.
Academic Article	Signal recognition particle: an essential protein-targeting machine.
Academic Article	Molecular mechanism of GTPase activation at the signal recognition particle (SRP) RNA distal end.
Academic Article	Sestrin2 is a leucine sensor for the mTORC1 pathway.
Academic Article	KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Academic Article	Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
Academic Article	Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.
Academic Article	Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.
Academic Article	SecYEG activates GTPases to drive the completion of cotranslational protein targeting.
Academic Article	An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids.
Academic Article	Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.
Grant	A Molecular Study of Rag GTPase-Dependent Amino Acid Sensing
Academic Article	Purification and biochemical characterization of the Rag GTPase heterodimer.
Academic Article	A New Crosslinking Assay to Study Guanine Nucleotide Binding in the Gtr Heterodimer of S. cerevisiae.
Academic Article	Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells.

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GTP Phosphohydrolases