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Shen, Kuang

One or more keywords matched the following items that are connected to Shen, Kuang

Item Type	Name
Concept	Membrane Proteins
Concept	Protein Binding
Concept	Protein Subunits
Concept	Protein Transport
Concept	Protein Processing, Post-Translational
Concept	Protein Kinase Inhibitors
Concept	Carrier Proteins
Concept	Protein Biosynthesis
Concept	Nuclear Proteins
Concept	Recombinant Proteins
Concept	Cyclic AMP-Dependent Protein Kinases
Concept	Protein Precursors
Concept	Protein Interaction Domains and Motifs
Concept	Intracellular Signaling Peptides and Proteins
Concept	Monomeric GTP-Binding Proteins
Concept	Repressor Proteins
Concept	Proteins
Concept	Ribosomal Proteins
Concept	Protein Structure, Tertiary
Concept	Protein Multimerization
Concept	Escherichia coli Proteins
Concept	Bacterial Proteins
Concept	Protein Stability
Concept	Protein Structure, Quaternary
Concept	Microfilament Proteins
Concept	Arabidopsis Proteins
Concept	Protein Conformation
Concept	Proto-Oncogene Proteins
Concept	Light-Harvesting Protein Complexes
Concept	GTPase-Activating Proteins
Concept	Nerve Tissue Proteins
Concept	Tumor Suppressor Proteins
Academic Article	Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex.
Academic Article	The structural basis of FtsY recruitment and GTPase activation by SRP RNA.
Academic Article	Mechanism of an ATP-independent protein disaggregase: II. distinct molecular interactions drive multiple steps during aggregate disassembly.
Academic Article	Activated GTPase movement on an RNA scaffold drives co-translational protein targeting.
Academic Article	Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during cotranslational protein targeting.
Academic Article	The crystal structure of the signal recognition particle in complex with its receptor.
Academic Article	C7orf59/LAMTOR4 phosphorylation and structural flexibility modulate Ragulator assembly.
Academic Article	Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability.
Academic Article	Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
Academic Article	Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting.
Academic Article	ATP-independent reversal of a membrane protein aggregate by a chloroplast SRP subunit.
Academic Article	Signal recognition particle: an essential protein-targeting machine.
Academic Article	Molecular mechanism of GTPase activation at the signal recognition particle (SRP) RNA distal end.
Academic Article	Sestrin2 is a leucine sensor for the mTORC1 pathway.
Academic Article	Analyzing Single-Molecule Protein Transportation Experiments via Hierarchical Hidden Markov Models.
Academic Article	The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.
Academic Article	KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Academic Article	Two-step membrane binding by the bacterial SRP receptor enable efficient and accurate Co-translational protein targeting.
Academic Article	Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
Academic Article	Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.
Academic Article	Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.
Academic Article	A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity.
Academic Article	SecYEG activates GTPases to drive the completion of cotranslational protein targeting.
Academic Article	Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
Academic Article	An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids.
Academic Article	mTOR-Activating Mutations in RRAGD Are Causative for Kidney Tubulopathy and Cardiomyopathy.
Academic Article	Ribosome profiling reveals novel regulation of C9ORF72 GGGGCC repeat-containing RNA translation.
Concept	Protein Domains
Concept	C9orf72 Protein
Concept	Ras Homolog Enriched in Brain Protein
Concept	Protein Unfolding
Concept	Chloroplast Proteins
Academic Article	Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.
Academic Article	Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike.
Grant	A Molecular Study of Rag GTPase-Dependent Amino Acid Sensing
Academic Article	Purification and biochemical characterization of the Rag GTPase heterodimer.
Academic Article	A New Crosslinking Assay to Study Guanine Nucleotide Binding in the Gtr Heterodimer of S. cerevisiae.
Academic Article	Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination.
Academic Article	Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells.
Academic Article	Structure of the Schizosaccharomyces pombe Gtr-Lam complex reveals evolutionary divergence of mTORC1-dependent amino acid sensing.

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GTP Binding Proteins