| Item Type | Name |
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Academic Article
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Phosphorylation of the oncogenic transcription factor interferon regulatory factor 2 (IRF2) in vitro and in vivo.
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Academic Article
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Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis.
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Academic Article
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Differential roles of NMDA Receptor Subtypes NR2A and NR2B in dendritic branch development and requirement of RasGRF1.
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Academic Article
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Runx1 and C/EBP? transcription factors directly up-regulate P2X3 gene transcription.
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Academic Article
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Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability.
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Academic Article
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1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA.
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Academic Article
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Transcription of the pain-related TRPV1 gene requires Runx1 and C/EBP? factors.
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Concept
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Protein Subunits
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Concept
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Synaptosomes
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Concept
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RNA, Small Interfering
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Concept
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Oxidative Stress
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Concept
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Superior Colliculi
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Concept
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Mutagenesis, Site-Directed
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Concept
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Memory, Short-Term
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Concept
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Amyotrophic Lateral Sclerosis
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Concept
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Cell Survival
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Concept
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Histone Code
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Concept
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Genes, Dominant
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Concept
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Freund's Adjuvant
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Concept
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Synaptic Transmission
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Concept
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Stress, Physiological
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Concept
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Adult Stem Cells
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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Sodium
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Concept
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Sodium Channels
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Concept
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Spinal Nerves
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Concept
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Synaptic Potentials
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Concept
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Stem Cells
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Concept
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Signal Transduction
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Concept
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Ganglia, Spinal
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Concept
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Spinal Cord
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Concept
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Superoxide Dismutase
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Concept
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Reactive Oxygen Species
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Concept
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Protein Structure, Tertiary
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Concept
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Synapses
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Concept
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Dendritic Spines
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Concept
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Core Binding Factor Alpha 2 Subunit
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Concept
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Antigens, Surface
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Concept
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Electric Stimulation
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Concept
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Muscle Fibers, Skeletal
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Concept
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Wechsler Scales
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Concept
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Protein Structure, Quaternary
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Concept
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Core Binding Factor Alpha 1 Subunit
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Concept
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Binding Sites
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Concept
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Calcium Signaling
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Concept
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Brain Stem
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Concept
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Genome-Wide Association Study
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Concept
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Serine Endopeptidases
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Concept
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Mediator Complex Subunit 1
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Concept
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Rats, Sprague-Dawley
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Concept
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Serine
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Concept
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Lupus Erythematosus, Systemic
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Concept
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Superoxides
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Concept
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Gene Silencing
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Concept
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Muscle, Skeletal
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Concept
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Strychnine
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Concept
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Mice, Mutant Strains
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Academic Article
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Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons.
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Academic Article
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PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors.
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Academic Article
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Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B.
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Academic Article
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ALS-linked protein disulfide isomerase variants cause motor dysfunction.
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Academic Article
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Silencing strategies for therapy of SOD1-mediated ALS.
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Academic Article
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Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts.
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Academic Article
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Early pathogenesis in the adult-onset neurodegenerative disease amyotrophic lateral sclerosis.
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Academic Article
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Synaptic drive at developing synapses: transient upregulation of kainate receptors.
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Academic Article
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Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice.
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Academic Article
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Polycomb PRC2 complex mediates epigenetic silencing of a critical osteogenic master regulator in the hippocampus.
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Academic Article
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Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis.
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Academic Article
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Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution.
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Academic Article
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Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione.
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Academic Article
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Anti-homeostatic synaptic plasticity of glycine receptor function after chronic strychnine in developing cultured mouse spinal neurons.
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Academic Article
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Variable transcriptional responsiveness of the P2X3 receptor gene during CFA-induced inflammatory hyperalgesia.
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Academic Article
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Changes on the properties of glycine receptors during neuronal development.
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Academic Article
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Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress.
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Academic Article
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Developmental-dependent action of microtubule depolymerization on the function and structure of synaptic glycine receptor clusters in spinal neurons.
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Academic Article
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aV?3 Integrin regulates astrocyte reactivity.
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Academic Article
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Chronic infusion of SOD1G93A astrocyte-secreted factors induces spinal motoneuron degeneration and neuromuscular dysfunction in healthy rats.
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Academic Article
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Epigenetic Signatures at the RUNX2-P1 and Sp7 Gene Promoters Control Osteogenic Lineage Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells.
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Academic Article
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Glycinergic and GABAergic synaptic transmission are differentially affected by gephyrin in spinal neurons.
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Academic Article
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NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, and H3K27ac.
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Academic Article
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Alterations in the motor neuron-renshaw cell circuit in the Sod1(G93A) mouse model.
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Academic Article
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Glycine receptors involved in synaptic transmission are selectively regulated by the cytoskeleton in mouse spinal neurons.
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Academic Article
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ALS skeletal muscle shows enhanced TGF-? signaling, fibrosis and induction of fibro/adipogenic progenitor markers.
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Academic Article
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A Myosin Va mutant mouse with disruptions in glutamate synaptic development and mature plasticity in visual cortex.
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Academic Article
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Effects of chronic ethanol treatment on gamma-aminobutyric acid(A) and glycine receptors in mouse glycinergic spinal neurons.
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Academic Article
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Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer's disease mice.
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Academic Article
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Superoxide generation via the NR2B-NMDAR/RasGRF1/NOX2 pathway promotes dendritogenesis.
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Academic Article
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Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.
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Academic Article
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Interactive and additive influences of Gender, BMI and Apolipoprotein 4 on cognition in children chronically exposed to high concentrations of PM2.5 and ozone. APOE 4 females are at highest risk in Mexico City.
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Academic Article
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The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model.
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Academic Article
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Receptor compartmentalization and trafficking at glutamate synapses: a developmental proposal.
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Academic Article
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Dissecting the role of redox signaling in neuronal development.
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Academic Article
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Interfering of the Reelin/ApoER2/PSD95 Signaling Axis Reactivates Dendritogenesis of Mature Hippocampal Neurons.
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Academic Article
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Pathogenicity of lupus anti-ribosomal P antibodies: role of cross-reacting neuronal surface P antigen in glutamatergic transmission and plasticity in a mouse model.
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Academic Article
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Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling.
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Academic Article
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PSD95 regulates morphological development of adult-born granule neurons in the mouse hippocampus.
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Academic Article
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Epigenetic silencing of the osteoblast-lineage gene program during hippocampal maturation.
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Academic Article
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Downregulation of the Polycomb-Associated Methyltransferase Ezh2 during Maturation of Hippocampal Neurons Is Mediated by MicroRNAs Let-7 and miR-124.
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Academic Article
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Mast Cell and Astrocyte Hemichannels and Their Role in Alzheimer's Disease, ALS, and Harmful Stress Conditions.
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Academic Article
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BET bromodomain inhibitors PFI-1 and JQ1 are identified in an epigenetic compound screen to enhance C9ORF72 gene expression and shown to ameliorate C9ORF72-associated pathological and behavioral abnormalities in a C9ALS/FTD model.
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Concept
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Superoxide Dismutase-1
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Concept
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Sp7 Transcription Factor
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Concept
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Neural Stem Cells
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Concept
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Transcriptome
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Concept
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Voltage-Gated Sodium Channel Blockers
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Concept
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Endoplasmic Reticulum Stress
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Academic Article
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Astroglial gliotransmitters released via Cx43 hemichannels regulate NMDAR-dependent transmission and short-term fear memory in the basolateral amygdala.
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Academic Article
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H3K9 Methyltransferases Suv39h1 and Suv39h2 Control the Differentiation of Neural Progenitor Cells in the Adult Hippocampus.
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Academic Article
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Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons.
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Academic Article
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Epigenetic Changes and Chromatin Reorganization in Brain Function: Lessons from Fear Memory Ensemble and Alzheimer's Disease.
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Academic Article
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Protein kinase B (AKT) upregulation and Thy-1-av?3?integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis.
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Academic Article
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Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43A90V mutation display a mild reactive state and release polyP toxic to motoneurons.
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Academic Article
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c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration.
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Academic Article
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Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD.
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Academic Article
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Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death.
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Academic Article
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Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death.
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