| Item Type | Name |
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Sandhoff Disease
|
|
Concept
|
Imaging, Three-Dimensional
|
|
Concept
|
NF-kappa B
|
|
Concept
|
Humans
|
|
Concept
|
Genetic Therapy
|
|
Concept
|
Cell Nucleus
|
|
Concept
|
Magnetic Resonance Imaging
|
|
Concept
|
Gene Expression
|
|
Concept
|
Nitric Oxide
|
|
Concept
|
Fluorescent Dyes
|
|
Concept
|
Surgery, Computer-Assisted
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Injections
|
|
Concept
|
Cell Adhesion
|
|
Concept
|
Dependovirus
|
|
Concept
|
Video Recording
|
|
Concept
|
Culture Media
|
|
Concept
|
Calcium
|
|
Concept
|
Coronary Vessels
|
|
Concept
|
Tay-Sachs Disease
|
|
Concept
|
Sarcoplasmic Reticulum Calcium-Transporting ATPases
|
|
Concept
|
Injections, Spinal
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
Mice
|
|
Concept
|
Electromagnetic Fields
|
|
Concept
|
Thalamus
|
|
Concept
|
Capillaries
|
|
Concept
|
Cattle
|
|
Concept
|
Transgenes
|
|
Concept
|
Morphogenesis
|
|
Concept
|
Sarcoplasmic Reticulum
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Gene Expression Regulation
|
|
Concept
|
Mutation
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Huntington Disease
|
|
Concept
|
Biomechanical Phenomena
|
|
Concept
|
Cytoplasm
|
|
Concept
|
Cerebellopontine Angle
|
|
Concept
|
Drug Administration Routes
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Microscopy, Fluorescence
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Proto-Oncogene Proteins c-raf
|
|
Concept
|
Cell Membrane
|
|
Concept
|
Electrolytes
|
|
Concept
|
Green Fluorescent Proteins
|
|
Concept
|
G(M2) Ganglioside
|
|
Concept
|
Sheep
|
|
Concept
|
Maple Syrup Urine Disease
|
|
Concept
|
Transduction, Genetic
|
|
Concept
|
Cisterna Magna
|
|
Concept
|
beta-N-Acetylhexosaminidases
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
Rats
|
|
Concept
|
Diabetes Mellitus, Type 1
|
|
Concept
|
Tomography, X-Ray Computed
|
|
Concept
|
Electricity
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Neovascularization, Physiologic
|
|
Concept
|
Genetic Vectors
|
|
Concept
|
MAP Kinase Kinase 4
|
|
Concept
|
Diabetes Mellitus, Experimental
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
|
|
Concept
|
Gene Transfer Techniques
|
|
Academic Article
|
A Safe and Reliable Technique for CNS Delivery of AAV Vectors in the Cisterna Magna.
|
|
Academic Article
|
Imaging NF-?B activity in a murine model of early stage diabetes.
|
|
Academic Article
|
Canine Models of Inherited Musculoskeletal and Neurodegenerative Diseases.
|
|
Academic Article
|
Volume and Infusion Rate Dynamics of Intraparenchymal Central Nervous System Infusion in a Large Animal Model.
|
|
Academic Article
|
Pronounced Therapeutic Benefit of a Single Bidirectional AAV Vector Administered Systemically in Sandhoff Mice.
|
|
Academic Article
|
Regulation of endothelial MAPK/ERK signalling and capillary morphogenesis by low-amplitude electric field.
|
|
Academic Article
|
Angiogenic microenvironment augments impaired endothelial responses under diabetic conditions.
|
|
Academic Article
|
Modulation of cell function by electric field: a high-resolution analysis.
|
|
Academic Article
|
Diabetes alters intracellular calcium transients in cardiac endothelial cells.
|
|
Academic Article
|
Natural history of Tay-Sachs disease in sheep.
|
|
Academic Article
|
Real-time MR tracking of AAV gene therapy with ?gal-responsive MR probe in a murine model of GM1-gangliosidosis.
|
|
Academic Article
|
Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep.
|
|
Concept
|
White Matter
|
|
Academic Article
|
Brain Alterations in Aged OVT73 Sheep Model of Huntington's Disease: An MRI Based Approach.
|
|
Academic Article
|
Levels of Synaptic Proteins in Brain and Neurofilament Light Chain in Cerebrospinal Fluid and Plasma of OVT73 Huntington's Disease Sheep Support a Prodromal Disease State.
|
|
Academic Article
|
Awake intracerebroventricular delivery and safety assessment of oligonucleotides in a large animal model.
|
|
Academic Article
|
A minimally invasive endovascular approach to the cerebellopontine angle cistern enables broad CNS biodistribution of scAAV9-CB-GFP.
|
|
Academic Article
|
BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease.
|