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Alterman, Julia

One or more keywords matched the following items that are connected to Alterman, Julia

Item Type	Name
Concept	Huntington Disease
Academic Article	Loss of huntingtin function slows synaptic vesicle endocytosis in striatal neurons from the httQ140/Q140 mouse model of Huntington's disease.
Academic Article	Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificity.
Academic Article	Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington's disease models.
Academic Article	A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system.

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